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Protein

Protein AraJ

Gene

araJ

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May be involved in either the transport or processing of arabinose polymers.

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

BioCyciEcoCyc:ARAJ-MONOMER.
ECOL316407:JW0386-MONOMER.

Protein family/group databases

TCDBi2.A.1.2.14. the major facilitator superfamily (mfs).

Names & Taxonomyi

Protein namesi
Recommended name:
Protein AraJ
Gene namesi
Name:araJ
Ordered Locus Names:b0396, JW0386
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10060. araJ.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 44CytoplasmicSequence analysis
Transmembranei5 – 2723HelicalSequence analysisAdd
BLAST
Topological domaini28 – 4114PeriplasmicSequence analysisAdd
BLAST
Transmembranei42 – 6322HelicalSequence analysisAdd
BLAST
Topological domaini64 – 696CytoplasmicSequence analysis
Transmembranei70 – 8920HelicalSequence analysisAdd
BLAST
Topological domaini90 – 934PeriplasmicSequence analysis
Transmembranei94 – 11623HelicalSequence analysisAdd
BLAST
Topological domaini117 – 12812CytoplasmicSequence analysisAdd
BLAST
Transmembranei129 – 15123HelicalSequence analysisAdd
BLAST
Topological domaini152 – 1554PeriplasmicSequence analysis
Transmembranei156 – 17823HelicalSequence analysisAdd
BLAST
Topological domaini179 – 19820CytoplasmicSequence analysisAdd
BLAST
Transmembranei199 – 22123HelicalSequence analysisAdd
BLAST
Topological domaini222 – 23514PeriplasmicSequence analysisAdd
BLAST
Transmembranei236 – 25520HelicalSequence analysisAdd
BLAST
Topological domaini256 – 2616CytoplasmicSequence analysis
Transmembranei262 – 28423HelicalSequence analysisAdd
BLAST
Topological domaini285 – 2939PeriplasmicSequence analysis
Transmembranei294 – 31623HelicalSequence analysisAdd
BLAST
Topological domaini317 – 3226CytoplasmicSequence analysis
Transmembranei323 – 34220HelicalSequence analysisAdd
BLAST
Topological domaini343 – 3519PeriplasmicSequence analysis
Transmembranei352 – 37423HelicalSequence analysisAdd
BLAST
Topological domaini375 – 39420CytoplasmicSequence analysisAdd
BLAST

GO - Cellular componenti

  • integral component of membrane Source: UniProtKB-KW
  • plasma membrane Source: EcoCyc
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 394394Protein AraJPRO_0000084832Add
BLAST

Proteomic databases

PaxDbiP23910.

Expressioni

Inductioni

By arabinose.

Interactioni

Protein-protein interaction databases

BioGridi4263172. 18 interactions.
STRINGi511145.b0396.

Structurei

3D structure databases

ProteinModelPortaliP23910.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the major facilitator superfamily.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105F27. Bacteria.
COG2814. LUCA.
HOGENOMiHOG000136927.
InParanoidiP23910.
KOiK08156.
OMAiMCISNSL.
PhylomeDBiP23910.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23910-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKVILSLAL GTFGLGMAEF GIMGVLTELA HNVGISIPAA GHMISYYALG
60 70 80 90 100
VVVGAPIIAL FSSRYSLKHI LLFLVALCVI GNAMFTLSSS YLMLAIGRLV
110 120 130 140 150
SGFPHGAFFG VGAIVLSKII KPGKVTAAVA GMVSGMTVAN LLGIPLGTYL
160 170 180 190 200
SQEFSWRYTF LLIAVFNIAV MASVYFWVPD IRDEAKGNLR EQFHFLRSPA
210 220 230 240 250
PWLIFAATMF GNAGVFAWFS YVKPYMMFIS GFSETAMTFI MMLVGLGMVL
260 270 280 290 300
GNMLSGRISG RYSPLRIAAV TDFIIVLALL MLFFCGGMKT TSLIFAFICC
310 320 330 340 350
AGLFALSAPL QILLLQNAKG GELLGAAGGQ IAFNLGSAVG AYCGGMMLTL
360 370 380 390
GLAYNYVALP AALLSFAAMS SLLLYGRYKR QQAADTPVLA KPLG
Length:394
Mass (Da):41,926
Last modified:March 1, 1992 - v1
Checksum:i40C1B0F1451A817A
GO

Sequence cautioni

The sequence AAB18120 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64787 Genomic DNA. Translation: AAA23474.1.
U73857 Genomic DNA. Translation: AAB18120.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73499.1.
AP009048 Genomic DNA. Translation: BAE76176.1.
PIRiB43750.
RefSeqiNP_414930.3. NC_000913.3.
WP_001326926.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC73499; AAC73499; b0396.
BAE76176; BAE76176; BAE76176.
GeneIDi949077.
KEGGiecj:JW0386.
eco:b0396.
PATRICi32115935. VBIEscCol129921_0409.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64787 Genomic DNA. Translation: AAA23474.1.
U73857 Genomic DNA. Translation: AAB18120.1. Different initiation.
U00096 Genomic DNA. Translation: AAC73499.1.
AP009048 Genomic DNA. Translation: BAE76176.1.
PIRiB43750.
RefSeqiNP_414930.3. NC_000913.3.
WP_001326926.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP23910.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4263172. 18 interactions.
STRINGi511145.b0396.

Protein family/group databases

TCDBi2.A.1.2.14. the major facilitator superfamily (mfs).

Proteomic databases

PaxDbiP23910.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC73499; AAC73499; b0396.
BAE76176; BAE76176; BAE76176.
GeneIDi949077.
KEGGiecj:JW0386.
eco:b0396.
PATRICi32115935. VBIEscCol129921_0409.

Organism-specific databases

EchoBASEiEB0058.
EcoGeneiEG10060. araJ.

Phylogenomic databases

eggNOGiENOG4105F27. Bacteria.
COG2814. LUCA.
HOGENOMiHOG000136927.
InParanoidiP23910.
KOiK08156.
OMAiMCISNSL.
PhylomeDBiP23910.

Enzyme and pathway databases

BioCyciEcoCyc:ARAJ-MONOMER.
ECOL316407:JW0386-MONOMER.

Miscellaneous databases

PROiP23910.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiIPR011701. MFS.
IPR020846. MFS_dom.
[Graphical view]
PfamiPF07690. MFS_1. 1 hit.
[Graphical view]
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiPS50850. MFS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiARAJ_ECOLI
AccessioniPrimary (citable) accession number: P23910
Secondary accession number(s): Q2MC30
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 1992
Last sequence update: March 1, 1992
Last modified: September 7, 2016
This is version 123 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.