Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

P23903

- E13B_BACCI

UniProt

P23903 - E13B_BACCI

Protein

Glucan endo-1,3-beta-glucosidase A1

Gene

glcA

Organism
Bacillus circulans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Nov 1991)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Lysis of cellular walls containing beta-1,3-glucans. Implicated in the defense against fungal pathogens.

    Catalytic activityi

    Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei552 – 5521NucleophilePROSITE-ProRule annotation
    Active sitei557 – 5571Proton donorPROSITE-ProRule annotation

    GO - Molecular functioni

    1. glucan endo-1,3-beta-D-glucosidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Cell wall biogenesis/degradation

    Protein family/group databases

    CAZyiGH16. Glycoside Hydrolase Family 16.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glucan endo-1,3-beta-glucosidase A1 (EC:3.2.1.39)
    Alternative name(s):
    (1->3)-beta-glucan endohydrolase
    (1->3)-beta-glucanase A1
    Gene namesi
    Name:glcA
    OrganismiBacillus circulans
    Taxonomic identifieri1397 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

    Subcellular locationi

    Secreted By similarity

    GO - Cellular componenti

    1. extracellular region Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Secreted

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 38381 PublicationAdd
    BLAST
    Chaini39 – 682644Glucan endo-1,3-beta-glucosidase A1PRO_0000011796Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP23903.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyl hydrolase 16 family.Curated

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000757. Glyco_hydro_16.
    IPR008263. Glycoside_hydrolase_16_AS.
    [Graphical view]
    PfamiPF00722. Glyco_hydro_16. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    PROSITEiPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P23903-1 [UniParc]FASTAAdd to Basket

    « Hide

    MKPSHFTEKR FMKKVLGLFL VVVMLASVGV LPTSKVQAAG TTVTSMEYFS    50
    PADGPVISKS GVGKASYGFV MPKFNGGSAT WNDVYSDVGV NVKVGNNWVD 100
    IDQAGGYIYN QNWGHWSDGG FNGYWFTLSA TTEIQLYSKA NGVKLEYQLV 150
    FQNINKTTIT AMNPTQGPQI TASFTGGAGF TYPTFNNDSA VTYEAVADDL 200
    KVYVKPVNSS SWIDIDNNAA SGWIYDHNFG QFTDGGGGYW FNVTESINVK 250
    LESKTSSANL VYTITFNEPT RNSYVITPYE GTTFTADANG SIGIPLPKID 300
    GGAPIAKELG NFVYQINING QWVDLSNSSQ SKFAYSANGY NNMSDANQWG 350
    YWADYIYGLW FQPIQENMQI RIGYPLNGQA GGNIGNNFVN YTFIGNPNAP 400
    RPDVSDQEDI SIGTPTDPAI AGMNLIWQDE FNGTTLDTSK WNYETGYYLN 450
    NDPATWGWGN AELQHYTNST QNVYVQDGKL NIKAMNDSKS FPQDPNRYAQ 500
    YSSGKINTKD KLSLKYGRVD FRAKLPTGDG VWPALWMLPK DSVYGTWAAS 550
    GEIDVMEARG RLPGSVSGTI HFGGQWPVNQ SSGGDYHFPE GQTFANDYHV 600
    YSVVWEEDNI KWYVDGKFFY KVTNQQWYST AAPNNPNAPF DEPFYLIMNL 650
    AVGGNFDGGR TPNASDIPAT MQVDYVRVYK EQ 682
    Length:682
    Mass (Da):75,466
    Last modified:November 1, 1991 - v1
    Checksum:i8C4F407E34D4ADD5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M34503 Genomic DNA. Translation: AAA22474.1.
    PIRiJQ0420.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M34503 Genomic DNA. Translation: AAA22474.1 .
    PIRi JQ0420.

    3D structure databases

    ProteinModelPortali P23903.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH16. Glycoside Hydrolase Family 16.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR000757. Glyco_hydro_16.
    IPR008263. Glycoside_hydrolase_16_AS.
    [Graphical view ]
    Pfami PF00722. Glyco_hydro_16. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    PROSITEi PS01034. GLYCOSYL_HYDROL_F16. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structure of the gene encoding beta-1,3-glucanase A1 of Bacillus circulans WL-12."
      Yahata N., Watanabe T., Nakamura Y., Yamamoto Y., Kamimiya S., Tanaka H.
      Gene 86:113-117(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 39-52.
      Strain: WL-12.

    Entry informationi

    Entry nameiE13B_BACCI
    AccessioniPrimary (citable) accession number: P23903
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: November 1, 1991
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Direct protein sequencing

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3