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P23903

- E13B_BACCI

UniProt

P23903 - E13B_BACCI

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Protein

Glucan endo-1,3-beta-glucosidase A1

Gene

glcA

Organism
Bacillus circulans
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Lysis of cellular walls containing beta-1,3-glucans. Implicated in the defense against fungal pathogens.

Catalytic activityi

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei552 – 5521NucleophilePROSITE-ProRule annotation
Active sitei557 – 5571Proton donorPROSITE-ProRule annotation

GO - Molecular functioni

  1. glucan endo-1,3-beta-D-glucosidase activity Source: UniProtKB-EC

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
  2. cell wall organization Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Cell wall biogenesis/degradation

Protein family/group databases

CAZyiGH16. Glycoside Hydrolase Family 16.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucan endo-1,3-beta-glucosidase A1 (EC:3.2.1.39)
Alternative name(s):
(1->3)-beta-glucan endohydrolase
(1->3)-beta-glucanase A1
Gene namesi
Name:glcA
OrganismiBacillus circulans
Taxonomic identifieri1397 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Subcellular locationi

Secreted By similarity

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 38381 PublicationAdd
BLAST
Chaini39 – 682644Glucan endo-1,3-beta-glucosidase A1PRO_0000011796Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP23903.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 16 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
[Graphical view]
PfamiPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P23903-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKPSHFTEKR FMKKVLGLFL VVVMLASVGV LPTSKVQAAG TTVTSMEYFS
60 70 80 90 100
PADGPVISKS GVGKASYGFV MPKFNGGSAT WNDVYSDVGV NVKVGNNWVD
110 120 130 140 150
IDQAGGYIYN QNWGHWSDGG FNGYWFTLSA TTEIQLYSKA NGVKLEYQLV
160 170 180 190 200
FQNINKTTIT AMNPTQGPQI TASFTGGAGF TYPTFNNDSA VTYEAVADDL
210 220 230 240 250
KVYVKPVNSS SWIDIDNNAA SGWIYDHNFG QFTDGGGGYW FNVTESINVK
260 270 280 290 300
LESKTSSANL VYTITFNEPT RNSYVITPYE GTTFTADANG SIGIPLPKID
310 320 330 340 350
GGAPIAKELG NFVYQINING QWVDLSNSSQ SKFAYSANGY NNMSDANQWG
360 370 380 390 400
YWADYIYGLW FQPIQENMQI RIGYPLNGQA GGNIGNNFVN YTFIGNPNAP
410 420 430 440 450
RPDVSDQEDI SIGTPTDPAI AGMNLIWQDE FNGTTLDTSK WNYETGYYLN
460 470 480 490 500
NDPATWGWGN AELQHYTNST QNVYVQDGKL NIKAMNDSKS FPQDPNRYAQ
510 520 530 540 550
YSSGKINTKD KLSLKYGRVD FRAKLPTGDG VWPALWMLPK DSVYGTWAAS
560 570 580 590 600
GEIDVMEARG RLPGSVSGTI HFGGQWPVNQ SSGGDYHFPE GQTFANDYHV
610 620 630 640 650
YSVVWEEDNI KWYVDGKFFY KVTNQQWYST AAPNNPNAPF DEPFYLIMNL
660 670 680
AVGGNFDGGR TPNASDIPAT MQVDYVRVYK EQ
Length:682
Mass (Da):75,466
Last modified:November 1, 1991 - v1
Checksum:i8C4F407E34D4ADD5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34503 Genomic DNA. Translation: AAA22474.1.
PIRiJQ0420.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M34503 Genomic DNA. Translation: AAA22474.1 .
PIRi JQ0420.

3D structure databases

ProteinModelPortali P23903.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH16. Glycoside Hydrolase Family 16.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.120.200. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
[Graphical view ]
Pfami PF00722. Glyco_hydro_16. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
PROSITEi PS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure of the gene encoding beta-1,3-glucanase A1 of Bacillus circulans WL-12."
    Yahata N., Watanabe T., Nakamura Y., Yamamoto Y., Kamimiya S., Tanaka H.
    Gene 86:113-117(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 39-52.
    Strain: WL-12.

Entry informationi

Entry nameiE13B_BACCI
AccessioniPrimary (citable) accession number: P23903
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 29, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3