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P23903 (E13B_BACCI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucan endo-1,3-beta-glucosidase A1

EC=3.2.1.39
Alternative name(s):
(1->3)-beta-glucan endohydrolase
(1->3)-beta-glucanase A1
Gene names
Name:glcA
OrganismBacillus circulans
Taxonomic identifier1397 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length682 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Lysis of cellular walls containing beta-1,3-glucans. Implicated in the defense against fungal pathogens.

Catalytic activity

Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 16 family.

Ontologies

Keywords
   Biological processCell wall biogenesis/degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucan endo-1,3-beta-D-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 3838 Ref.1
Chain39 – 682644Glucan endo-1,3-beta-glucosidase A1
PRO_0000011796

Sites

Active site5521Nucleophile By similarity
Active site5571Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
P23903 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 8C4F407E34D4ADD5

FASTA68275,466
        10         20         30         40         50         60 
MKPSHFTEKR FMKKVLGLFL VVVMLASVGV LPTSKVQAAG TTVTSMEYFS PADGPVISKS 

        70         80         90        100        110        120 
GVGKASYGFV MPKFNGGSAT WNDVYSDVGV NVKVGNNWVD IDQAGGYIYN QNWGHWSDGG 

       130        140        150        160        170        180 
FNGYWFTLSA TTEIQLYSKA NGVKLEYQLV FQNINKTTIT AMNPTQGPQI TASFTGGAGF 

       190        200        210        220        230        240 
TYPTFNNDSA VTYEAVADDL KVYVKPVNSS SWIDIDNNAA SGWIYDHNFG QFTDGGGGYW 

       250        260        270        280        290        300 
FNVTESINVK LESKTSSANL VYTITFNEPT RNSYVITPYE GTTFTADANG SIGIPLPKID 

       310        320        330        340        350        360 
GGAPIAKELG NFVYQINING QWVDLSNSSQ SKFAYSANGY NNMSDANQWG YWADYIYGLW 

       370        380        390        400        410        420 
FQPIQENMQI RIGYPLNGQA GGNIGNNFVN YTFIGNPNAP RPDVSDQEDI SIGTPTDPAI 

       430        440        450        460        470        480 
AGMNLIWQDE FNGTTLDTSK WNYETGYYLN NDPATWGWGN AELQHYTNST QNVYVQDGKL 

       490        500        510        520        530        540 
NIKAMNDSKS FPQDPNRYAQ YSSGKINTKD KLSLKYGRVD FRAKLPTGDG VWPALWMLPK 

       550        560        570        580        590        600 
DSVYGTWAAS GEIDVMEARG RLPGSVSGTI HFGGQWPVNQ SSGGDYHFPE GQTFANDYHV 

       610        620        630        640        650        660 
YSVVWEEDNI KWYVDGKFFY KVTNQQWYST AAPNNPNAPF DEPFYLIMNL AVGGNFDGGR 

       670        680 
TPNASDIPAT MQVDYVRVYK EQ 

« Hide

References

[1]"Structure of the gene encoding beta-1,3-glucanase A1 of Bacillus circulans WL-12."
Yahata N., Watanabe T., Nakamura Y., Yamamoto Y., Kamimiya S., Tanaka H.
Gene 86:113-117(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 39-52.
Strain: WL-12.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M34503 Genomic DNA. Translation: AAA22474.1.
PIRJQ0420.

3D structure databases

ProteinModelPortalP23903.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH16. Glycoside Hydrolase Family 16.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D2.60.120.200. 1 hit.
InterProIPR008985. ConA-like_lec_gl_sf.
IPR013320. ConA-like_subgrp.
IPR000757. Glyco_hydro_16.
IPR008263. Glycoside_hydrolase_16_AS.
[Graphical view]
PfamPF00722. Glyco_hydro_16. 1 hit.
[Graphical view]
SUPFAMSSF49899. SSF49899. 1 hit.
PROSITEPS01034. GLYCOSYL_HYDROL_F16. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameE13B_BACCI
AccessionPrimary (citable) accession number: P23903
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 16, 2013
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries