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Protein

Uncharacterized protein YfeA

Gene

yfeA

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11145-MONOMER.
ECOL316407:JW5391-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YfeA
Gene namesi
Name:yfeA
Ordered Locus Names:b2395, JW5391
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11145. yfeA.

Subcellular locationi

GO - Cellular componenti

  • plasma membrane Source: EcoCyc
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 729729Uncharacterized protein YfeAPRO_0000169216Add
BLAST

Proteomic databases

PaxDbiP23842.

Expressioni

Inductioni

Expressed during exponential and post-exponential growth at both 28 and 37 degrees Celsius. Repressed by RpoS.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4259186. 204 interactions.
DIPiDIP-12011N.
IntActiP23842. 1 interaction.
MINTiMINT-1223642.
STRINGi511145.b2395.

Structurei

3D structure databases

ProteinModelPortaliP23842.
SMRiP23842. Positions 491-726.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini348 – 476129GGDEFPROSITE-ProRule annotationAdd
BLAST
Domaini488 – 729242EALPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 EAL domain.PROSITE-ProRule annotation
Contains 1 GGDEF domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4108KMM. Bacteria.
ENOG41100B0. LUCA.
HOGENOMiHOG000122953.
InParanoidiP23842.
OMAiSVRFDMQ.
PhylomeDBiP23842.

Family and domain databases

CDDicd01948. EAL. 1 hit.
Gene3Di3.20.20.450. 1 hit.
InterProiIPR001633. EAL_dom.
IPR000160. GGDEF_dom.
IPR007895. MASE1.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00563. EAL. 1 hit.
PF05231. MASE1. 1 hit.
[Graphical view]
SMARTiSM00052. EAL. 1 hit.
SM00267. GGDEF. 1 hit.
[Graphical view]
SUPFAMiSSF141868. SSF141868. 1 hit.
SSF55073. SSF55073. 1 hit.
PROSITEiPS50883. EAL. 1 hit.
PS50887. GGDEF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23842-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFVEHNLIKN IKIFTLAFTL TVVLIQLSRF ISPLAIIHSS YIFLAWMPLC
60 70 80 90 100
VMLSILFIFG WRGVVPVLCG MFCTNLWNFH LSFLQTAVML GSQTFVVLCA
110 120 130 140 150
CAILRWQLGT RWRYGLTSRY VWQRLFWLGL VTPIGIKCSM YLVGSFFDFP
160 170 180 190 200
LKISTFFGDA DAIFTVVDLL SLFTAVLIYN MLFYYLTRMI VSPHFAQILW
210 220 230 240 250
RRDIAPSLGK EKRAFTLSWL AALSVLLLLL CTPYENDFIA GYLVPVFFII
260 270 280 290 300
FTLGVGKLRY PFLNLTWAVS TLCLLNYNQN FLQGVETEYS LAFILAVLIS
310 320 330 340 350
FSVCLLYMVR IYHRSEWLNR RWHLQALTDP LTLLPNFRAL EQAPEQEAGK
360 370 380 390 400
SFCCLRIDNL EFMSRHYGLM MRVHCIRSIC RTLLPLMQEN EKLYQLPGSE
410 420 430 440 450
LLLVLSGPET EGRLQHMVNI LNSRQIHWNN TGLDMGYGAA WGRFDGNQET
460 470 480 490 500
LQPLLGQLSW LAEQSCAHHH VLALDSREEM VSGQTTKQVL LLNTIRTALD
510 520 530 540 550
QGDLLLYAQP IRNKEGEGYD EILARLKYDG GIMTPDKFLP LIAQFNLSAR
560 570 580 590 600
FDLQVLESLL KWLATHPCDK KGPRFSVNLM PLTLLQKNIA GRIIRLFKRY
610 620 630 640 650
HISPQAVILE ITEEQAFSNA ESSMYNIEQL HKFGFRIAID DFGTGYANYE
660 670 680 690 700
RLKRLQADII KIDGVFVKDI VTNTLDAMIV RSITDLAKAK SLSVVAEFVE
710 720
TQQQQALLHK LGVQYLQGYL IGRPQPLAD
Length:729
Mass (Da):83,524
Last modified:April 27, 2001 - v2
Checksum:iF1CF1AA15D592650
GO

Sequence cautioni

The sequence AAA65719 differs from that shown. Reason: Frameshift at position 112. Curated
The sequence AAA65719 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated
The sequence CAA45395 differs from that shown. Reason: Frameshift at position 112. Curated
The sequence CAA45395 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75454.2.
AP009048 Genomic DNA. Translation: BAA16267.2.
M13687 Genomic DNA. Translation: AAA65719.1. Sequence problems.
X63976 Genomic DNA. Translation: CAA45395.1. Sequence problems.
PIRiH65013.
S11411.
RefSeqiNP_416896.4. NC_000913.3.
WP_000497400.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75454; AAC75454; b2395.
BAA16267; BAA16267; BAA16267.
GeneIDi946864.
KEGGiecj:JW5391.
eco:b2395.
PATRICi32120167. VBIEscCol129921_2492.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U00096 Genomic DNA. Translation: AAC75454.2.
AP009048 Genomic DNA. Translation: BAA16267.2.
M13687 Genomic DNA. Translation: AAA65719.1. Sequence problems.
X63976 Genomic DNA. Translation: CAA45395.1. Sequence problems.
PIRiH65013.
S11411.
RefSeqiNP_416896.4. NC_000913.3.
WP_000497400.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP23842.
SMRiP23842. Positions 491-726.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4259186. 204 interactions.
DIPiDIP-12011N.
IntActiP23842. 1 interaction.
MINTiMINT-1223642.
STRINGi511145.b2395.

Proteomic databases

PaxDbiP23842.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75454; AAC75454; b2395.
BAA16267; BAA16267; BAA16267.
GeneIDi946864.
KEGGiecj:JW5391.
eco:b2395.
PATRICi32120167. VBIEscCol129921_2492.

Organism-specific databases

EchoBASEiEB1135.
EcoGeneiEG11145. yfeA.

Phylogenomic databases

eggNOGiENOG4108KMM. Bacteria.
ENOG41100B0. LUCA.
HOGENOMiHOG000122953.
InParanoidiP23842.
OMAiSVRFDMQ.
PhylomeDBiP23842.

Enzyme and pathway databases

BioCyciEcoCyc:EG11145-MONOMER.
ECOL316407:JW5391-MONOMER.

Miscellaneous databases

PROiP23842.

Family and domain databases

CDDicd01948. EAL. 1 hit.
Gene3Di3.20.20.450. 1 hit.
InterProiIPR001633. EAL_dom.
IPR000160. GGDEF_dom.
IPR007895. MASE1.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF00563. EAL. 1 hit.
PF05231. MASE1. 1 hit.
[Graphical view]
SMARTiSM00052. EAL. 1 hit.
SM00267. GGDEF. 1 hit.
[Graphical view]
SUPFAMiSSF141868. SSF141868. 1 hit.
SSF55073. SSF55073. 1 hit.
PROSITEiPS50883. EAL. 1 hit.
PS50887. GGDEF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiYFEA_ECOLI
AccessioniPrimary (citable) accession number: P23842
Secondary accession number(s): P76529, P76954
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: April 27, 2001
Last modified: September 7, 2016
This is version 131 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.