P23840 (DIND_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
DNA-damage-inducible protein D

Gene names

Name:	dinD
Synonyms:	pcsA, yicD
Ordered Locus Names:	b3645, JW3620

Organism

Escherichia coli (strain K12)

Taxonomic identifier

83333 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Escherichia

Protein attributes

Sequence length	274 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Miscellaneous	Essential for E.coli under special growth condition.
Sequence caution	The sequence AAA61998.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 274	274	DNA-damage-inducible protein D		PRO_0000079902

Sequences

	Sequence		Length	Mass (Da)
	P23840 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 27ADCBAF6AF98D12	FASTA	274	31,078
	10 20 30 40 50 60 MNEHHQPFEE IKLINANGAE QWSARQLGKL LGYSEYRHFI PVLTRAKEAC ENSGHTIDDH 70 80 90 100 110 120 FEEILDMVKI GSNAKRALKD IVLSRYACYL VVQNGDPAKP VIAAGQTYFA IQTRRQELAD 130 140 150 160 170 180 DEAFKQLRED EKRLFLRNEL KEHNKQLVEA AQQAGVATAT DFAIFQNHGY QGLYGGLDQK 190 200 210 220 230 240 AIHQRKGLKK NQKILDHMGS TELAANLFRA TQTEEKLKRD GVNSKQQANT THFDVGRKVR 250 260 270 QTIQELGGTM PEELPTPQVS IKQLENSVKI TEKK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Molecular and mutational analysis of three genes preceding pyrE on the Escherichia coli chromosome." Poulsen P., Andersen J.T., Jensen K.F. Mol. Microbiol. 3:393-404(1989) [PubMed: 2664418] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: K12.
[2]	"DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication." Burland V.D., Plunkett G. III, Daniels D.L., Blattner F.R. Genomics 16:551-561(1993) [PubMed: 7686882] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[3]	"The complete genome sequence of Escherichia coli K-12." Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y. Science 277:1453-1474(1997) [PubMed: 9278503] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / MG1655 / ATCC 47076.
[4]	"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110." Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T. Mol. Syst. Biol. 2:E1-E5(2006) [PubMed: 16738553] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[5]	"Bacterial transposon Tn7 utilizes two different classes of target sites." Kubo K.M., Craig N.L. J. Bacteriol. 172:2774-2778(1990) [PubMed: 2158980] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 137-167.
[6]	"Three genes preceding pyrE on the Escherichia coli chromosome are essential for survival and normal cell morphology in stationary culture and at high temperature." Poulsen P., Jensen K.F. Res. Microbiol. 142:283-288(1991) [PubMed: 1925027] [Abstract] Cited for: IMPORTANCE AT HIGH TEMPERATURE.
[7]	"The DNA damage-inducible dinD gene of Escherichia coli is equivalent to orfY upstream of pyrE." Lundegaard C., Jensen K.F. J. Bacteriol. 176:3383-3385(1994) [PubMed: 8195095] [Abstract] Cited for: IDENTIFICATION OF GENE.
[8]	"Identification of high affinity binding sites for LexA which define new DNA damage-inducible genes in Escherichia coli." Lewis K.L., Harlow G.R., Gregg-Jolly L.A., Mount D.W. J. Mol. Biol. 241:507-523(1994) [PubMed: 8057377] [Abstract] Cited for: IDENTIFICATION OF GENE.
[9]	"The pcsA gene is identical to dinD in Escherichia coli." Ohmori H., Saito M., Yasuda T., Nagata T., Fujii T., Wachi M., Nagai K. J. Bacteriol. 177:156-165(1995) [PubMed: 8002613] [Abstract] Cited for: IDENTIFICATION OF GENE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X14235 Genomic DNA. Translation: CAA32452.1. L10328 Genomic DNA. Translation: AAA61998.1. Different initiation. U00096 Genomic DNA. Translation: AAC76669.2. AP009048 Genomic DNA. Translation: BAE77648.1. M31529 Genomic DNA. No translation available.
PIR	G65165.
RefSeq	NP_418102.2. NC_000913.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
IntAct	P23840. 6 interactions.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBESCT00000000328; EBESCP00000000328; EBESCG00000000265. EBESCT00000015342; EBESCP00000014633; EBESCG00000014402.
GeneID	948153.
GenomeReviews	Gene locus JW3620 in contig AP009048_GR. Gene locus b3645 in contig U00096_GR.
KEGG	ecj:JW3620. eco:b3645.
PATRIC	32122777. VBIEscCol129921_3765.
Organism-specific databases
EchoBASE	EB1179.
EcoGene	EG11193. dinD.
Phylogenomic databases
eggNOG	NOG11994.
GeneTree	EBGT00050000010441.
HOGENOM	HBG612431.
OMA	QKVRQTI.
ProtClustDB	PRK11525.
Enzyme and pathway databases
BioCyc	EcoCyc:EG11193-MONOMER.
Gene expression databases
Genevestigator	P23840.
Family and domain databases
KO	K14623.
ProtoNet	Search...

Entry information

Entry name

DIND_ECOLI

Accession

Primary (citable) accession number: P23840
Secondary accession number(s): P76719, Q2M7V8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	January 25, 2012
This is version 79 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program