##gff-version 3
P23804	UniProtKB	Chain	1	489	.	.	.	ID=PRO_0000018650;Note=E3 ubiquitin-protein ligase Mdm2	
P23804	UniProtKB	Domain	26	109	.	.	.	Note=SWIB/MDM2;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU01273	
P23804	UniProtKB	Zinc finger	297	326	.	.	.	Note=RanBP2-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00322	
P23804	UniProtKB	Zinc finger	436	477	.	.	.	Note=RING-type;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00175	
P23804	UniProtKB	Region	1	110	.	.	.	Note=Necessary for interaction with USP2;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P23804	UniProtKB	Region	1	101	.	.	.	Note=Sufficient to promote the mitochondrial pathway of apoptosis;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Region	1	22	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Region	114	183	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Region	147	228	.	.	.	Note=Interaction with PYHIN1 and necessary for interaction with RFFL and RNF34;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Region	167	304	.	.	.	Note=Interaction with MTBP;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:10906133;Dbxref=PMID:10906133	
P23804	UniProtKB	Region	197	235	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Region	208	302	.	.	.	Note=ARF-binding	
P23804	UniProtKB	Region	221	230	.	.	.	Note=Interaction with USP7;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P23804	UniProtKB	Region	240	329	.	.	.	Note=Region II	
P23804	UniProtKB	Region	250	271	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Region	274	489	.	.	.	Note=Necessary for interaction with USP2;Ontology_term=ECO:0000250;evidence=ECO:0000250	
P23804	UniProtKB	Region	342	426	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Motif	176	182	.	.	.	Note=Nuclear localization signal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P23804	UniProtKB	Motif	183	195	.	.	.	Note=Nuclear export signal	
P23804	UniProtKB	Motif	464	471	.	.	.	Note=Nucleolar localization signal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P23804	UniProtKB	Compositional bias	159	183	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	199	216	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	217	235	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	250	268	.	.	.	Note=Acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	342	386	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	387	408	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Compositional bias	409	423	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P23804	UniProtKB	Modified residue	163	163	.	.	.	Note=Phosphoserine%3B by SGK1;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	183	183	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0007744;evidence=ECO:0007744|PubMed:21183079;Dbxref=PMID:21183079	
P23804	UniProtKB	Modified residue	238	238	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	240	240	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	244	244	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	258	258	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	260	260	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	394	394	.	.	.	Note=Phosphoserine%3B by ATM;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	406	406	.	.	.	Note=Phosphoserine%3B by ATM;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	417	417	.	.	.	Note=Phosphothreonine%3B by ATM;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	423	423	.	.	.	Note=Phosphoserine%3B by ATM;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Modified residue	427	427	.	.	.	Note=Phosphoserine%3B by ATM;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:Q00987	
P23804	UniProtKB	Alternative sequence	1	49	.	.	.	ID=VSP_003215;Note=In isoform Mdm2-p76. Missing;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P23804	UniProtKB	Mutagenesis	58	58	.	.	.	Note=Reduced interaction with NDUFS1%2C ROS production and apoptosis. G->I;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:30879903;Dbxref=PMID:30879903	
P23804	UniProtKB	Sequence conflict	203	203	.	.	.	Note=S->T;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P23804	UniProtKB	Sequence conflict	419	419	.	.	.	Note=D->H;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P23804	UniProtKB	Sequence conflict	486	486	.	.	.	Note=T->S;Ontology_term=ECO:0000305;evidence=ECO:0000305