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P23777 (PP1_BRANA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein phosphatase PP1

EC=3.1.3.16
OrganismBrassica napus (Rape)
Taxonomic identifier3708 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

Protein attributes

Sequence length255 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

Cofactor

Binds 2 manganese ions per subunit By similarity.

Sequence similarities

Belongs to the PPP phosphatase family. PP-1 subfamily.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 255›255Serine/threonine-protein phosphatase PP1
PRO_0000058805

Sites

Active site631Proton donor By similarity
Metal binding21Manganese 1 By similarity
Metal binding41Manganese 1 By similarity
Metal binding301Manganese 1 By similarity
Metal binding301Manganese 2 By similarity
Metal binding621Manganese 2 By similarity
Metal binding1111Manganese 2 By similarity
Metal binding1861Manganese 2 By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
P23777 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 7BA2A62C12221D05

FASTA25528,850
        10         20         30         40         50         60 
GDIHGQYQDL LRLFEYGGYP PSANFLFLGD YVDRGKQSLE TICLLLAYKI RYPSKIYLLR 

        70         80         90        100        110        120 
GNHEDAKINR IYGFYDECKR RFNVRLWKIF TDCFNCLPVA ALIDDKILCM HGGLSPELDN 

       130        140        150        160        170        180 
LNQIREIQRP TEIPDSGLLC DLLWSDPDQK IEGWADSDRG ISCTFGADKV AEFLDKNDLD 

       190        200        210        220        230        240 
LICRGHQVVE DGYEFFAKRR LVTIFSAPNY GGEFDNAGAL LSVDESLVCS FEIMKPALAS 

       250 
SSGHPLKKVP KMGKS 

« Hide

References

[1]"Identification by molecular cloning of two cDNA sequences from the plant Brassica napus which are very similar to mammalian protein phosphatases-1 and -2A."
Mackintosh R.W., Haycox G., Hardie D.G., Cohen P.T.W.
FEBS Lett. 276:156-160(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X57438 mRNA. Translation: CAA40686.1.
PIRS12985.

3D structure databases

ProteinModelPortalP23777.
SMRP23777. Positions 1-237.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEP23777.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.60.21.10. 1 hit.
InterProIPR004843. Calcineurin-like_PHP_apaH.
IPR029052. Metallo-depent_PP-like.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamPF00149. Metallophos. 1 hit.
[Graphical view]
PRINTSPR00114. STPHPHTASE.
SMARTSM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMSSF56300. SSF56300. 1 hit.
PROSITEPS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePP1_BRANA
AccessionPrimary (citable) accession number: P23777
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: June 11, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families