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P23777

- PP1_BRANA

UniProt

P23777 - PP1_BRANA

Protein

Serine/threonine-protein phosphatase PP1

Gene
N/A
Organism
Brassica napus (Rape)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 67 (01 Oct 2014)
      Sequence version 1 (01 Nov 1991)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

    Cofactori

    Binds 2 manganese ions per subunit.By similarity

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi2 – 21Manganese 1By similarity
    Metal bindingi4 – 41Manganese 1By similarity
    Metal bindingi30 – 301Manganese 1By similarity
    Metal bindingi30 – 301Manganese 2By similarity
    Metal bindingi62 – 621Manganese 2By similarity
    Active sitei63 – 631Proton donorBy similarity
    Metal bindingi111 – 1111Manganese 2By similarity
    Metal bindingi186 – 1861Manganese 2By similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. phosphoprotein phosphatase activity Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase, Protein phosphatase

    Keywords - Ligandi

    Manganese, Metal-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphatase PP1 (EC:3.1.3.16)
    OrganismiBrassica napus (Rape)
    Taxonomic identifieri3708 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeBrassiceaeBrassica

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini‹1 – 255›255Serine/threonine-protein phosphatase PP1PRO_0000058805Add
    BLAST

    Proteomic databases

    PRIDEiP23777.

    Structurei

    3D structure databases

    ProteinModelPortaliP23777.
    SMRiP23777. Positions 1-237.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family. PP-1 subfamily.Curated

    Family and domain databases

    Gene3Di3.60.21.10. 1 hit.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF00149. Metallophos. 1 hit.
    [Graphical view]
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 1 hit.
    PROSITEiPS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    P23777-1 [UniParc]FASTAAdd to Basket

    « Hide

    GDIHGQYQDL LRLFEYGGYP PSANFLFLGD YVDRGKQSLE TICLLLAYKI    50
    RYPSKIYLLR GNHEDAKINR IYGFYDECKR RFNVRLWKIF TDCFNCLPVA 100
    ALIDDKILCM HGGLSPELDN LNQIREIQRP TEIPDSGLLC DLLWSDPDQK 150
    IEGWADSDRG ISCTFGADKV AEFLDKNDLD LICRGHQVVE DGYEFFAKRR 200
    LVTIFSAPNY GGEFDNAGAL LSVDESLVCS FEIMKPALAS SSGHPLKKVP 250
    KMGKS 255
    Length:255
    Mass (Da):28,850
    Last modified:November 1, 1991 - v1
    Checksum:i7BA2A62C12221D05
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X57438 mRNA. Translation: CAA40686.1.
    PIRiS12985.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X57438 mRNA. Translation: CAA40686.1 .
    PIRi S12985.

    3D structure databases

    ProteinModelPortali P23777.
    SMRi P23777. Positions 1-237.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P23777.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.60.21.10. 1 hit.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR029052. Metallo-depent_PP-like.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF00149. Metallophos. 1 hit.
    [Graphical view ]
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 1 hit.
    PROSITEi PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification by molecular cloning of two cDNA sequences from the plant Brassica napus which are very similar to mammalian protein phosphatases-1 and -2A."
      Mackintosh R.W., Haycox G., Hardie D.G., Cohen P.T.W.
      FEBS Lett. 276:156-160(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiPP1_BRANA
    AccessioniPrimary (citable) accession number: P23777
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: November 1, 1991
    Last modified: October 1, 2014
    This is version 67 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3