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Protein

Glutamine synthetase

Gene
N/A
Organism
Lactuca sativa (Garden lettuce)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Miscellaneous

Irreversibly inhibited by the herbicide L-phosphinothricin (PPT).

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Alternative name(s):
GS(1)
Glutamate--ammonia ligase
OrganismiLactuca sativa (Garden lettuce)
Taxonomic identifieri4236 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeCichorioideaeCichorieaeLactucinaeLactuca

Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001531741 – 358Glutamine synthetaseAdd BLAST358

Proteomic databases

PRIDEiP23712

Interactioni

Subunit structurei

Homooctamer.

Structurei

3D structure databases

ProteinModelPortaliP23712
SMRiP23712
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Family and domain databases

Gene3Di3.10.20.70, 1 hit
InterProiView protein in InterPro
IPR008147 Gln_synt_b-grasp
IPR036651 Gln_synt_N
IPR014746 Gln_synth/guanido_kin_cat_dom
IPR008146 Gln_synth_cat_dom
IPR027303 Gln_synth_gly_rich_site
IPR027302 Gln_synth_N_conserv_site
PfamiView protein in Pfam
PF00120 Gln-synt_C, 1 hit
PF03951 Gln-synt_N, 1 hit
SMARTiView protein in SMART
SM01230 Gln-synt_C, 1 hit
SUPFAMiSSF54368 SSF54368, 1 hit
SSF55931 SSF55931, 1 hit
PROSITEiView protein in PROSITE
PS00180 GLNA_1, 1 hit
PS00181 GLNA_ATP, 1 hit

Sequencei

Sequence statusi: Complete.

P23712-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALLSDLVNL DLSSITDKII AEYIWIGGSG MDLRSKARTL SGPVSDPSEL
60 70 80 90 100
PKWNYDGSST GQAPGEDSEV IIYPQAIFKD PFRRGNHILV MCDAYTPAGE
110 120 130 140 150
PIPTNKRAAA AKIFSNPEVE KEVTWYGIEQ EYTLLQKDTN WPLGWPLGGF
160 170 180 190 200
PGPQGPYYCG IGADKAFGRD IVDAHYKACL YAGVNISGIN GEVMPGQWEF
210 220 230 240 250
QVGPSVGIAA ADQIWVARYI LERITEIYGV VVSFDPKPIP GDWNGAGAHT
260 270 280 290 300
NYSTKTMREE GGYEVIKKAI EKLGLRHKEH IAAYGEGNER RLTGRHETAD
310 320 330 340 350
INTFLWGVAN RGASIRVGRD TEKEGKGYFE DRRPASNMDP YVVTSMIAET

TILWDNKS
Length:358
Mass (Da):39,470
Last modified:November 1, 1995 - v2
Checksum:i789A4E731DDDFBEB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X60092 mRNA Translation: CAA42689.1
PIRiS11965 AJLCQB
UniGeneiLsa.50

Similar proteinsi

Entry informationi

Entry nameiGLNA_LACSA
AccessioniPrimary (citable) accession number: P23712
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 80 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

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