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P23661

- GUNB_RUMAL

UniProt

P23661 - GUNB_RUMAL

Protein

Endoglucanase B

Gene

celB

Organism
Ruminococcus albus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 74 (01 Oct 2014)
      Sequence version 1 (01 Nov 1991)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei212 – 2121Proton donorBy similarity
    Active sitei332 – 3321NucleophileBy similarity

    GO - Molecular functioni

    1. cellulase activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellulose catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Glycosidase, Hydrolase

    Keywords - Biological processi

    Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

    Protein family/group databases

    CAZyiGH5. Glycoside Hydrolase Family 5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Endoglucanase B (EC:3.2.1.4)
    Alternative name(s):
    Cellulase B
    Endo-1,4-beta-glucanase B
    Short name:
    EGB
    Gene namesi
    Name:celB
    OrganismiRuminococcus albus
    Taxonomic identifieri1264 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121PROSITE-ProRule annotationAdd
    BLAST
    Chaini22 – 409388Endoglucanase BPRO_0000007872Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP23661.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Signal

    Family and domain databases

    Gene3Di3.20.20.80. 1 hit.
    InterProiIPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view]
    PfamiPF00150. Cellulase. 1 hit.
    [Graphical view]
    SUPFAMiSSF51445. SSF51445. 1 hit.
    PROSITEiPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P23661-1 [UniParc]FASTAAdd to Basket

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    MKLKRIAALL TAAVMSVGVM ASCGGSKSDD KSKADTKSAA ETSGAEGDSS    50
    ESEEIPVSQT HTNDPMTVTS AKDLVAKMSN GWNLGNTMDA TGEGLESEIS 100
    WLPTKVYTNK FMIDMLPEAG FNVLRIPVSW GNHLIDNNYT IDPAWMDRVQ 150
    EIVNYGIDDG MYVILNTHHE EWYMPKPSEK DGDIEELKAI WSQIADRFKG 200
    YDEHLIFEGL NEPRLRGEGA EWTGTSEARE IINEYEKAFV ETVRASGGNN 250
    GDRCLMITGY AASSGYNNLS AIELPEDSDK LIISVHAYLP YSFALDTKGT 300
    DKYDPEDTAI PTLFESLNEL FISRDIPVIV GEFGSMNKDN IDDRVKCLDD 350
    YLGNAAKYDI PCVWWDNYAR IGNGENFGLL NRQEYDWYFP KLMDVFKKYA 400
    ESDPSAAAA 409
    Length:409
    Mass (Da):45,524
    Last modified:November 1, 1991 - v1
    Checksum:i119081DFA3BFDD54
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54932 Genomic DNA. Translation: CAA38693.1.
    PIRiS12018.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X54932 Genomic DNA. Translation: CAA38693.1 .
    PIRi S12018.

    3D structure databases

    ProteinModelPortali P23661.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    CAZyi GH5. Glycoside Hydrolase Family 5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.20.20.80. 1 hit.
    InterProi IPR001547. Glyco_hydro_5.
    IPR018087. Glyco_hydro_5_CS.
    IPR013781. Glyco_hydro_catalytic_dom.
    IPR017853. Glycoside_hydrolase_SF.
    [Graphical view ]
    Pfami PF00150. Cellulase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51445. SSF51445. 1 hit.
    PROSITEi PS00659. GLYCOSYL_HYDROL_F5. 1 hit.
    PS51257. PROKAR_LIPOPROTEIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence of the Ruminococcus albus SY3 endoglucanase genes celA and celB."
      Poole D.M., Hazlewood G.P., Laurie J.I., Barker P.J., Gilbert H.J.
      Mol. Gen. Genet. 223:217-223(1990) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: SY3.

    Entry informationi

    Entry nameiGUNB_RUMAL
    AccessioniPrimary (citable) accession number: P23661
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: November 1, 1991
    Last modified: October 1, 2014
    This is version 74 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. Glycosyl hydrolases
      Classification of glycosyl hydrolase families and list of entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3