Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P23661 (GUNB_RUMAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase B

EC=3.2.1.4
Alternative name(s):
Cellulase B
Endo-1,4-beta-glucanase B
Short name=EGB
Gene names
Name:celB
OrganismRuminococcus albus
Taxonomic identifier1264 [NCBI]
Taxonomic lineageBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

Protein attributes

Sequence length409 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 409388Endoglucanase B
PRO_0000007872

Sites

Active site2121Proton donor By similarity
Active site3321Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P23661 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 119081DFA3BFDD54

FASTA40945,524
        10         20         30         40         50         60 
MKLKRIAALL TAAVMSVGVM ASCGGSKSDD KSKADTKSAA ETSGAEGDSS ESEEIPVSQT 

        70         80         90        100        110        120 
HTNDPMTVTS AKDLVAKMSN GWNLGNTMDA TGEGLESEIS WLPTKVYTNK FMIDMLPEAG 

       130        140        150        160        170        180 
FNVLRIPVSW GNHLIDNNYT IDPAWMDRVQ EIVNYGIDDG MYVILNTHHE EWYMPKPSEK 

       190        200        210        220        230        240 
DGDIEELKAI WSQIADRFKG YDEHLIFEGL NEPRLRGEGA EWTGTSEARE IINEYEKAFV 

       250        260        270        280        290        300 
ETVRASGGNN GDRCLMITGY AASSGYNNLS AIELPEDSDK LIISVHAYLP YSFALDTKGT 

       310        320        330        340        350        360 
DKYDPEDTAI PTLFESLNEL FISRDIPVIV GEFGSMNKDN IDDRVKCLDD YLGNAAKYDI 

       370        380        390        400 
PCVWWDNYAR IGNGENFGLL NRQEYDWYFP KLMDVFKKYA ESDPSAAAA 

« Hide

References

[1]"Nucleotide sequence of the Ruminococcus albus SY3 endoglucanase genes celA and celB."
Poole D.M., Hazlewood G.P., Laurie J.I., Barker P.J., Gilbert H.J.
Mol. Gen. Genet. 223:217-223(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: SY3.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X54932 Genomic DNA. Translation: CAA38693.1.
PIRS12018.

3D structure databases

ProteinModelPortalP23661.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
PS51257. PROKAR_LIPOPROTEIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUNB_RUMAL
AccessionPrimary (citable) accession number: P23661
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: February 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries