P23624 (SPO13_YEAST) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Meiosis-specific protein SPO13

Alternative name(s):
Sporulation-specific protein 13

Gene names

Name:	SPO13
Ordered Locus Names:	YHR014W

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

Taxonomic identifier

559292 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Required for meiosis I segmentation.
Subcellular location	Nucleus Potential.

Ontologies

Keywords
Biological process	Meiosis Sporulation
Cellular component	Nucleus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	meiotic sister chromatid cohesion Inferred from mutant phenotype. Source: SGD positive regulation of sister chromatid cohesion Inferred from physical interaction. Source: SGD protein localization to chromosome, centromeric region Inferred from mutant phenotype. Source: SGD sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	condensed nuclear chromosome, centromeric region Inferred from direct assay. Source: SGD
Molecular function	protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
CDC5	P32562	8	EBI-17719,EBI-4440

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 291	291	Meiosis-specific protein SPO13		PRO_0000072134
Regions
	Motif	3 – 6	4	Nuclear localization signal Potential

Sequences

	Sequence		Length	Mass (Da)
	P23624 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 3E277368AF234298	FASTA	291	33,295
	10 20 30 40 50 60 MAPRKRFRLL ELGSPTHSKR KVQKPLQEKT PNLRVSPLAF KIGKEIKNKE IRKTKKTESE 70 80 90 100 110 120 NIFNSKHVDL RLESPHPGLN FVSDAQQYSK AGDVRYLKNK SSNTLKNERQ TIERPSFDNS 130 140 150 160 170 180 LRFEDIEQPP KSTSTPVLSQ SSQINVEREA PMFPVPYYIA PSPMYNFSPY QNFVGNPTFL 190 200 210 220 230 240 TPSHNPNLNY AIPIQRPELL YPNVNVYDSP LFKKTRLPHQ TKSLDKEKNY QYLPIYPVSI 250 260 270 280 290 SNNGDFVGQE TPRAAPKLSK KRLSNTLDVN CSDYESSGQN ATYNDSESSL N

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Nucleotide sequence and promoter analysis of SPO13, a meiosis-specific gene of Saccharomyces cerevisiae." Buckingham L.E., Wang H.T., Elder R.T., McCarroll R.M., Slater M.R., Esposito R.E. Proc. Natl. Acad. Sci. U.S.A. 87:9406-9410(1990) [PubMed: 2123556] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[3]	Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c.
[4]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M38357 Genomic DNA. Translation: AAA35071.1. U10400 Genomic DNA. Translation: AAB68941.1. AY557825 Genomic DNA. Translation: AAS56151.1. BK006934 Genomic DNA. Translation: DAA06703.1.
PIR	A38426.
RefSeq	NP_011878.1. NM_001179144.1.
3D structure databases
ProteinModelPortal	P23624.
ModBase	Search...
Protein-protein interaction databases
DIP	DIP-1655N.
IntAct	P23624. 4 interactions.
MINT	MINT-394689.
STRING	P23624.
Proteomic databases
PeptideAtlas	P23624.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	YHR014W; YHR014W; YHR014W.
GeneID	856405.
KEGG	sce:YHR014W.
NMPDR	fig|4932.3.peg.3023.
Organism-specific databases
CYGD	YHR014w.
SGD	S000001056. SPO13.
Phylogenomic databases
OrthoDB	EOG4GF6R4.
Gene expression databases
ArrayExpress	P23624.
Genevestigator	P23624.
GermOnline	YHR014W. Saccharomyces cerevisiae.
Family and domain databases
ProtoNet	Search...
Other
NextBio	981946.

Entry information

Entry name

SPO13_YEAST

Accession

Primary (citable) accession number: P23624
Secondary accession number(s): D3DKV9

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	January 25, 2012
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program