Reviewed, UniProtKB/Swiss-Prot P23551 (XYNA_BUTFI)

Names and origin

Protein names

Recommended name:
    Endo-1,4-beta-xylanase A
      Short name=Xylanase A
    EC=3.2.1.8
Alternative name(s):
    1,4-beta-D-xylan xylanohydrolase A

Gene names

Name:

xynA

Organism

Butyrivibrio fibrisolvens

Taxonomic identifier

831 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Lachnospiraceae › Butyrivibrio

Protein attributes

Sequence length	411 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	B.fibrisolvens is located in the rumen of ruminant animals, where it contributes to the animal's digestion of plant material by hydrolyzing hemicellulose with its xylanases.
Catalytic activity	Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Pathway	Glycan degradation; xylan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 10 (cellulase F) family.

Ontologies

Keywords
Biological process	Xylan degradation
Domain	Signal
Molecular function	Glycosidase Hydrolase
Gene Ontology (GO)
Biological process	xylan catabolic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	cation binding Inferred from electronic annotation. Source: InterPro endo-1,4-beta-xylanase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 33	33	Potential
	Chain	34 – 411	378	Endo-1,4-beta-xylanase A		PRO_0000007970
Sites
	Active site	201	1	Proton donor By similarity
	Active site	311	1	Nucleophile By similarity

Sequences

	Sequence		Length	Mass (Da)
	P23551-1 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 4EA4AC50D8979DD5	FASTA	411	46,659
	10 20 30 40 50 60 MKKFKIRKLM ARVLALALVF STFFMVSKVD ANAASYNLME TYGAKYGYSG NCVHTHMLRD 70 80 90 100 110 120 SRIVNAIKKD SNIVTLGNEM KPDYLLGSRQ ATLISVDEAK RLGYYIPSNY KERYVPKIDF 130 140 150 160 170 180 RTVDEAVKIC YENGLKMRGH TLVWHSQTPT WLFRENYSGN GRFVNTATMD ARLEFYVKSV 190 200 210 220 230 240 MGHFYSGKYG STLVYWDVCN ETLHAQNSGW EAVYGSNKTN AVYVKKAFNY AYQVLEQYKL 250 260 270 280 290 300 TNSVKLFYND YNTYMEVNDV IKLVNYINQG KKVCAGVGMQ SHLGTGFPSV DYYTNALNSF 310 320 330 340 350 360 LRAGFEVQIT ELDITNKGDY DLNNYAYRLF KNINAAKKNG GNISCITWWG PSDAETWIRN 370 380 390 400 410 EKPLIWSNIG VAKPAYDEVV KAFTETFGNP GSFTPQPTIT PQPTPTPSGQ T

References

[1]	"Cloning, sequencing, and expression of a xylanase gene from the anaerobic ruminal bacterium Butyrivibrio fibrisolvens." Mannarelli B.M., Evans S., Lee D. J. Bacteriol. 172:4247-4254(1990) [PubMed: 2198249] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 49.

Cross-references

Sequence databases
PIR	A37755.
3D structure databases
HSSP	HSSP built from PDB template 1B31 based on UniProtKB P56588.
ModBase	Search...
Protein family/group databases
CAZy	GH10. Glycoside Hydrolase Family 10.
Enzyme and pathway databases
BRENDA	3.2.1.8. 1431.
Family and domain databases
InterPro	IPR001000. Glyco_hydro_10. IPR013781. Glyco_hydro_sg_catalytic. [Graphical view]
Gene3D	G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
Pfam	PF00331. Glyco_hydro_10. 1 hit. [Graphical view]
PRINTS	PR00134. GLHYDRLASE10.
SMART	SM00633. Glyco_10. 1 hit. [Graphical view]
PROSITE	PS00591. GLYCOSYL_HYDROL_F10. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

XYNA_BUTFI

Accession

Primary (citable) accession number: P23551

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	June 16, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)