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Protein

Endo-1,4-beta-xylanase A

Gene

xynA

Organism
Butyrivibrio fibrisolvens
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

B.fibrisolvens is located in the rumen of ruminant animals, where it contributes to the animal's digestion of plant material by hydrolyzing hemicellulose with its xylanases.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei201 – 2011Proton donorBy similarity
Active sitei311 – 3111NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

GO - Biological processi

  1. xylan catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiGH10. Glycoside Hydrolase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase A (EC:3.2.1.8)
Short name:
Xylanase A
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene namesi
Name:xynA
OrganismiButyrivibrio fibrisolvens
Taxonomic identifieri831 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesLachnospiraceaeButyrivibrio

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3333Sequence AnalysisAdd
BLAST
Chaini34 – 411378Endo-1,4-beta-xylanase APRO_0000007970Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP23551.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
PROSITEiPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P23551-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKFKIRKLM ARVLALALVF STFFMVSKVD ANAASYNLME TYGAKYGYSG
60 70 80 90 100
NCVHTHMLRD SRIVNAIKKD SNIVTLGNEM KPDYLLGSRQ ATLISVDEAK
110 120 130 140 150
RLGYYIPSNY KERYVPKIDF RTVDEAVKIC YENGLKMRGH TLVWHSQTPT
160 170 180 190 200
WLFRENYSGN GRFVNTATMD ARLEFYVKSV MGHFYSGKYG STLVYWDVCN
210 220 230 240 250
ETLHAQNSGW EAVYGSNKTN AVYVKKAFNY AYQVLEQYKL TNSVKLFYND
260 270 280 290 300
YNTYMEVNDV IKLVNYINQG KKVCAGVGMQ SHLGTGFPSV DYYTNALNSF
310 320 330 340 350
LRAGFEVQIT ELDITNKGDY DLNNYAYRLF KNINAAKKNG GNISCITWWG
360 370 380 390 400
PSDAETWIRN EKPLIWSNIG VAKPAYDEVV KAFTETFGNP GSFTPQPTIT
410
PQPTPTPSGQ T
Length:411
Mass (Da):46,659
Last modified:November 1, 1991 - v1
Checksum:i4EA4AC50D8979DD5
GO

Sequence databases

PIRiA37755.

Cross-referencesi

Sequence databases

PIRiA37755.

3D structure databases

ProteinModelPortaliP23551.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00114.

Family and domain databases

Gene3Di3.20.20.80. 1 hit.
InterProiIPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
PROSITEiPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning, sequencing, and expression of a xylanase gene from the anaerobic ruminal bacterium Butyrivibrio fibrisolvens."
    Mannarelli B.M., Evans S., Lee D.
    J. Bacteriol. 172:4247-4254(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 49.

Entry informationi

Entry nameiXYNA_BUTFI
AccessioniPrimary (citable) accession number: P23551
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 1, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.