Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Endoglucanase

Gene

bglC

Organism
Bacillus subtilis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei65SubstrateBy similarity1
Binding sitei96SubstrateBy similarity1
Binding sitei131SubstrateBy similarity1
Active sitei169Proton donorBy similarity1
Binding sitei231SubstrateBy similarity1
Active sitei257NucleophileBy similarity1
Binding sitei291SubstrateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCarbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiCBM3 Carbohydrate-Binding Module Family 3
GH5 Glycoside Hydrolase Family 5

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase (EC:3.2.1.4)
Alternative name(s):
Carboxymethyl-cellulase
Short name:
CMCase
Short name:
Cellulase
Endo-1,4-beta-glucanase
Gene namesi
Name:bglC
OrganismiBacillus subtilis
Taxonomic identifieri1423 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 29Add BLAST29
ChainiPRO_000000784130 – 499EndoglucanaseAdd BLAST470

Structurei

3D structure databases

ProteinModelPortaliP23549
SMRiP23549
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini350 – 499CBM3PROSITE-ProRule annotationAdd BLAST150

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni69 – 70Substrate bindingBy similarity2
Regioni263 – 264Substrate bindingBy similarity2
Regioni296 – 298Substrate bindingBy similarity3

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107QWR Bacteria
COG2730 LUCA

Family and domain databases

Gene3Di2.60.40.710, 1 hit
InterProiView protein in InterPro
IPR008965 CBM2/CBM3_carb-bd_dom_sf
IPR001956 CBM3
IPR036966 CBM3_sf
IPR001547 Glyco_hydro_5
IPR018087 Glyco_hydro_5_CS
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00942 CBM_3, 1 hit
PF00150 Cellulase, 1 hit
SMARTiView protein in SMART
SM01067 CBM_3, 1 hit
SUPFAMiSSF49384 SSF49384, 1 hit
SSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS51172 CBM3, 1 hit
PS00659 GLYCOSYL_HYDROL_F5, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P23549-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRSISIFIT CLLITLLTMG GMLASPASAA GTKTPVAKNG QLSIKGTQLV
60 70 80 90 100
NRDGKAVQLK GISSHGLQWY GEYVNKDSLK WLRDDWGITV FRAAMYTADG
110 120 130 140 150
GIIDNPSVKN KMKEAVEAAK ELGIYVIIDW HILNDGNPNQ NKEKAKEFFK
160 170 180 190 200
EMSSLYGNTP NVIYEIANEP NGDVNWKRDI KPYAEEVISV IRKNDPDNII
210 220 230 240 250
IVGTGTWSQD VNDAADDQLK DANVMDALHF YAGTHGQFLR DKANYALSKG
260 270 280 290 300
APIFVTEWGT SDASGNGGVF LDQSREWLKY LDSKTISWVN WNLSDKQESS
310 320 330 340 350
SALKPGASKT GGWRLSDLSA SGTFVRENIL GTKDSTKDIP ETPAKDKPTQ
360 370 380 390 400
ENGISVQYRA GDGSMNSNQI RPQLQIKNNG NTTVDLKDVT ARYWYNAKNK
410 420 430 440 450
GQNVDCDYAQ LGCGNVTYKF VTLHKPKQGA DTYLELGFKN GTLAPGASTG
460 470 480 490
NIQLRLHNDD WSNYAQSGDY SFFKSNTFKT TKKITLYDQG KLIWGTEPN
Length:499
Mass (Da):55,169
Last modified:November 1, 1991 - v1
Checksum:i2E821E3D8BBACA04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D01057 Genomic DNA Translation: BAA00859.1
PIRiJN0111

Similar proteinsi

Entry informationi

Entry nameiGUN3_BACIU
AccessioniPrimary (citable) accession number: P23549
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: March 28, 2018
This is version 100 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health