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P23548 (GUN_PAEPO) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase

EC=3.2.1.4
Alternative name(s):
Cellulase
Endo-1,4-beta-glucanase
OrganismPaenibacillus polymyxa (Bacillus polymyxa)
Taxonomic identifier1406 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesPaenibacillaceaePaenibacillus

Protein attributes

Sequence length397 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Molecular functionGlycosidase
Hydrolase
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 397397Endoglucanase
PRO_0000184042

Sites

Active site1941Proton donor By similarity
Active site3171Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
P23548 [UniParc].

Last modified February 1, 1996. Version 2.
Checksum: B9C2E802C04F0A2A

FASTA39744,357
        10         20         30         40         50         60 
MKKKGLKKTF FVIASLVMGF TLYGYTPVSA DAASVKGYYH TQGNKIVDES GKEAAFNGLN 

        70         80         90        100        110        120 
WFGLETPNYT LHGLWSRSMD DMLDQVKKEG YNLIRLPYSN QLFDSSSRPD SIDYHKNPDL 

       130        140        150        160        170        180 
VGLNPIQIMD KLIEKAGQRG IQIILDRHRP GSGGQSELWY TSQYPESRWI SDWKMLADRY 

       190        200        210        220        230        240 
KNNPTVIGAD LHNEPHGQAS WGTGNASTDW RLAAQRAGNA ILSVNPNWLI LVEGVDHNVQ 

       250        260        270        280        290        300 
GNNSQYWWGG NLTGVANYPV VLDVPNRVVY SPHDYGPGVS SQPWFNDPAF PSNLPAIWDQ 

       310        320        330        340        350        360 
TWGYISKQNI APVLVGEFGG RNVDLSCPEG KWQNALVHYI GANNLYFTYW SLNPNSGDTG 

       370        380        390 
GLLLDDWTTW NRPKQDMLGR IMKPVVSVAQ QAEAAAE 

« Hide

References

[1]"Molecular cloning, expression, and characterization of endo-beta-1,4-glucanase genes from Bacillus polymyxa and Bacillus circulans."
Baird S.D., Johnson D.A., Seligy V.L.
J. Bacteriol. 172:1576-1586(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M33791 Genomic DNA. Translation: AAA22631.1.
PIRA35136.

3D structure databases

ProteinModelPortalP23548.
SMRP23548. Positions 34-380.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN_PAEPO
AccessionPrimary (citable) accession number: P23548
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: February 1, 1996
Last modified: October 16, 2013
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries