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Protein

Mitochondrial biogenesis regulation protein 1

Gene

MBR1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Participates in mitochondrial biogenesis and stress response.2 Publications

GO - Biological processi

  • aerobic respiration Source: SGD

Keywordsi

Biological processStress response

Enzyme and pathway databases

BioCyciYEAST:G3O-31884-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial biogenesis regulation protein 1
Gene namesi
Name:MBR1
Ordered Locus Names:YKL093W
ORF Names:YKL440
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XI

Organism-specific databases

EuPathDBiFungiDB:YKL093W
SGDiS000001576 MBR1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000962711 – 339Mitochondrial biogenesis regulation protein 1Add BLAST339

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei159PhosphothreonineCombined sources1
Modified residuei177PhosphoserineCombined sources1
Modified residuei224PhosphoserineCombined sources1
Modified residuei227PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiP23493
PRIDEiP23493

PTM databases

iPTMnetiP23493

Expressioni

Inductioni

Expression is induced in the late growth phase and is negatively controlled by the cAMP-dependent protein kinase A (PKA).1 Publication

Interactioni

Protein-protein interaction databases

BioGridi34040, 122 interactors
DIPiDIP-4119N
MINTiP23493
STRINGi4932.YKL093W

Structurei

3D structure databases

ProteinModelPortaliP23493
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ISF1/MBR1 family.Curated

Phylogenomic databases

InParanoidiP23493
OrthoDBiEOG092C42IL

Family and domain databases

InterProiView protein in InterPro
IPR031443 Mbr1
PfamiView protein in Pfam
PF17058 MBR1, 1 hit

Sequencei

Sequence statusi: Complete.

P23493-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRMEKTTDKP LSAGDMNDEY SRGPIDDIDC LNFFERAVQD PCCEACDTED
60 70 80 90 100
ADEELRAKLS SFNFQPDSSP CNAKCQQTLN PLCKIDEALP AESELAPSRN
110 120 130 140 150
GSVSEANSDT NSIASTVHDP VDSKYGGMPS LRKAKTTSYF TSSSSNNTTM
160 170 180 190 200
RNPLKKCNTN INGLLVNGRS SSSSRQSIPE LFSGACTKKK NNVLLKSETP
210 220 230 240 250
NSEFSSNSLQ HCNSRSFSLP RSRSRSSAIA IPTHLYGLEK YVSPGLDTLT
260 270 280 290 300
ADPEESIERF SNNRPREISS CCPNDTGDTS SSLSHSNTSS SLNFPLGTNT
310 320 330
NQFHQPRQPV QQQQSSKPNF GAGRKKSFIE MSLASSFAG
Length:339
Mass (Da):36,935
Last modified:June 1, 1994 - v2
Checksum:iA38E7EA7049754A0
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti88A → G in AAA88725 (PubMed:8208248).Curated1
Sequence conflicti168G → R in AAA88725 (PubMed:8208248).Curated1
Sequence conflicti206S → T in AAA88725 (PubMed:8208248).Curated1
Sequence conflicti245G → E in AAA88725 (PubMed:8208248).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63309 Genomic DNA Translation: AAA88725.1
X71133 Genomic DNA Translation: CAA50464.1
Z28093 Genomic DNA Translation: CAA81931.1
X75561 Genomic DNA Translation: CAA53240.1
AY899251 mRNA Translation: AAX83936.1
BK006944 Genomic DNA Translation: DAA09065.1
PIRiS37920
RefSeqiNP_012830.1, NM_001179659.1

Genome annotation databases

EnsemblFungiiYKL093W; YKL093W; YKL093W
GeneIDi853769
KEGGisce:YKL093W

Similar proteinsi

Entry informationi

Entry nameiMBR1_YEAST
AccessioniPrimary (citable) accession number: P23493
Secondary accession number(s): D6VXJ5, Q2VQW7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: June 1, 1994
Last modified: May 23, 2018
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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