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Protein

Protein FecR

Gene

fecR

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regulation of iron dicitrate transport. In the absence of citrate FecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm.

GO - Biological processi

Keywordsi

Biological processIon transport, Iron transport, Sensory transduction, Transport
LigandIron

Enzyme and pathway databases

BioCyciEcoCyc:EG10292-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FecR
Gene namesi
Name:fecR
Ordered Locus Names:b4292, JW4252
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG10292 fecR

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000872181 – 317Protein FecRAdd BLAST317

Proteomic databases

PaxDbiP23485
PRIDEiP23485

Expressioni

Inductioni

Induced by hydroxyurea.1 Publication

Interactioni

Protein-protein interaction databases

DIPiDIP-9589N
IntActiP23485, 3 interactors
STRINGi316385.ECDH10B_4490

Structurei

3D structure databases

ProteinModelPortaliP23485
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG4108S3W Bacteria
COG3712 LUCA
HOGENOMiHOG000258943
InParanoidiP23485
KOiK07165
OMAiIMVTSGH
PhylomeDBiP23485

Family and domain databases

InterProiView protein in InterPro
IPR006860 FecR
IPR032508 FecR_C
IPR032623 FecR_N
IPR012373 Ferrdict_sens_TM
PANTHERiPTHR30273 PTHR30273, 1 hit
PfamiView protein in Pfam
PF16220 DUF4880, 1 hit
PF16344 DUF4974, 1 hit
PF04773 FecR, 1 hit
PIRSFiPIRSF018266 FecR, 1 hit

Sequencei

Sequence statusi: Complete.

P23485-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPLLTDSRR QALRSASHWY AVLSGERVSP QQEARWQQWY EQDQDNQWAW
60 70 80 90 100
QQVENLRNQL GGVPGDVASR ALHDTRLTRR HVMKGLLLLL GAGGGWQLWQ
110 120 130 140 150
SETGEGLRAD YRTAKGTVSR QQLEDGSLLT LNTQSAADVR FDAHQRTVRL
160 170 180 190 200
WYGEIAITTA KDALQRPFRV LTRQGQLTAL GTEFTVRQQD NFTQLDVQQH
210 220 230 240 250
AVEVLLASAP AQKRIVNAGE SLQFSASEFG AVKPLDDEST SWTKDILSFS
260 270 280 290 300
DKPLGEVIAT LTRYRNGVLR CDPAVAGLRL SGTFPLKNTD AILNVIAQTL
310
PVKIQSITRY WINISPL
Length:317
Mass (Da):35,532
Last modified:November 1, 1991 - v1
Checksum:i798EC615815AF9D7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M63115 Genomic DNA Translation: AAA23767.1
U14003 Genomic DNA Translation: AAA97188.1
U00096 Genomic DNA Translation: AAC77248.1
AP009048 Genomic DNA Translation: BAE78283.1
PIRiB37804
RefSeqiNP_418712.1, NC_000913.3
WP_001068910.1, NZ_LN832404.1

Genome annotation databases

EnsemblBacteriaiAAC77248; AAC77248; b4292
BAE78283; BAE78283; BAE78283
GeneIDi949104
KEGGiecj:JW4252
eco:b4292
PATRICifig|1411691.4.peg.2407

Entry informationi

Entry nameiFECR_ECOLI
AccessioniPrimary (citable) accession number: P23485
Secondary accession number(s): Q2M623
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
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