P23448 (FLIG_BACSU) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Flagellar motor switch protein FliG

Gene names

Name:	fliG
Ordered Locus Names:	BSU16220

Organism

Bacillus subtilis

Taxonomic identifier

1423 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

Protein attributes

Sequence length	338 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	One of the proteins that form a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation.
Subcellular location	Cell membrane; Peripheral membrane protein; Cytoplasmic side By similarity. Bacterial flagellum basal body By similarity.
Sequence similarities	Belongs to the FliG family.

Ontologies

Keywords
Biological process	Chemotaxis Flagellar rotation
Cellular component	Bacterial flagellum Cell membrane Membrane
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	chemotaxis Inferred from electronic annotation. Source: UniProtKB-KW ciliary or flagellar motility Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	bacterial-type flagellum basal body Inferred from electronic annotation. Source: UniProtKB-SubCell plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	motor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 338	338	Flagellar motor switch protein FliG		PRO_0000184082

Sequences

	Sequence		Length	Mass (Da)
	P23448 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 8C44193BA0ADE58E	FASTA	338	38,191
	10 20 30 40 50 60 MARRDQDKLT GKQKAAILMI SLGLDVSASV YKHLTDEEIE RLTLEISGVR SVDHQKKDEI 70 80 90 100 110 120 IEEFHNIAIA QDYISQGGLS YARQVLEKAL GEDKAENILN RLTSSLQVKP FDFARKAEPE 130 140 150 160 170 180 QILNFIQQEH PQTMALILSY LDPVQAGQIL SELNPEVQAE VARRIAVMDR TSPEIINEVE 190 200 210 220 230 240 RILEQKLSSA FTQDYTQTGG IEAVVEVLNG VDRGTEKTIL DSLEIQDPDL AEEIKKRMFV 250 260 270 280 290 300 FEDIVTLDNR AIQRVIRDVE NDDLLLSLKV ASEEVKEIVF NNMSQRMVET FKEEMEFMGP 310 320 330 VRLKDVEEAQ SRIVSIVRKL EEAGEIVIAR GGGDDIIV

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The flaA locus of Bacillus subtilis is part of a large operon coding for flagellar structures, motility functions, and an ATPase-like polypeptide." Albertini A.M., Caramori T., Crabb W.D., Scoffone F., Galizzi A. J. Bacteriol. 173:3573-3579(1991) [PubMed: 1828465] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 168.
[2]	"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis." Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A. Nature 390:249-256(1997) [PubMed: 9384377] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 168.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X56049 Genomic DNA. Translation: CAA39521.1. AL009126 Genomic DNA. Translation: CAB13495.1.
PIR	B42365.
RefSeq	NP_389504.1. NC_000964.3.
3D structure databases
ProteinModelPortal	P23448.
SMR	P23448. Positions 6-338.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000000550; EBBACP00000000550; EBBACG00000000548.
GeneID	937577.
GenomeReviews	Gene locus BSU16220 in contig AL009126_GR.
KEGG	bsu:BSU16220.
NMPDR	fig|224308.1.peg.1624.
PATRIC	18975049. VBIBacSub10457_1716.
Organism-specific databases
GenoList	BSU16220. [Micado]
Phylogenomic databases
GeneTree	EBGT00050000000585.
HOGENOM	HBG368483.
OMA	ESLKWMD.
PhylomeDB	P23448.
ProtClustDB	PRK05686.
Enzyme and pathway databases
BioCyc	BSUB:BSU16220-MONOMER.
Family and domain databases
InterPro	IPR000090. Flg_Motor_Flig. IPR023087. Flg_Motor_Flig_C. IPR011002. FliG_a-hlx. [Graphical view]
Gene3D	G3DSA:1.10.220.30. Flg_Motor_Flig_C. 1 hit.
KO	K02410.
Pfam	PF01706. FliG_C. 1 hit. [Graphical view]
PRINTS	PR00954. FLGMOTORFLIG.
SUPFAM	SSF48029. FliG_like. 2 hits.
TIGRFAMs	TIGR00207. FliG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FLIG_BACSU

Accession

Primary (citable) accession number: P23448

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	January 25, 2012
This is version 89 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program