P23370 (RS6_THETH) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
30S ribosomal protein S6

Alternative name(s):
TS9

Gene names

Name:	rpsF
Synonyms:	rps6

Organism

Thermus thermophilus

Taxonomic identifier

274 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Located on the outer edge of the platform on the body of the 30S subunit By similarity. HAMAP MF_00360
Subunit structure	Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S18 By similarity.
Sequence similarities	Belongs to the ribosomal protein S6P family.

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Direct protein sequencing
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 101

101

30S ribosomal protein S6 HAMAP MF_00360

PRO_0000176864

Secondary structure

1

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101

Helix Strand Turn

Details...

Beta strand

2 – 10

9

Helix

16 – 32

17

Beta strand

36 – 52

17

Beta strand

55 – 67

13

Helix

69 – 71

3

Helix

72 – 80

9

Beta strand

85 – 92

8

Sequences

	Sequence		Length	Mass (Da)
	P23370 [UniParc]. Last modified April 1, 1993. Version 2. Checksum: 4FEE8005C74902E5	FASTA	101	11,973
	10 20 30 40 50 60 MRRYEVNIVL NPNLDQSQLA LEKEIIQRAL ENYGARVEKV EELGLRRLAY PIAKDPQGYF 70 80 90 100 LWYQVEMPED RVNDLARELR IRDNVRRVMV VKSQEPFLAN A

References

[1]	"Sequencing and analysis of the Thermus thermophilus gene cluster equivalent to the S6 operon." Shcherbakov D.V., Cherepanova E.A., Garber M.B. Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: VK1.
[2]	"Crystals of protein S6 from the 30 S ribosomal subunit of Thermus thermophilus." Sedelnikova S.E., Agalarov S.C., Eliseikina I.A., Fomenkova N.P., Nikonov S.V., Garber M.B., Svensson L.A., Liljas A. J. Mol. Biol. 220:549-550(1991) [PubMed: 1870121] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-24.
[3]	"Ribosomal proteins from Thermus thermophilus for structural investigations." Garber M.B., Agalarov S.C., Eliseikina I.A., Fomenkova N.P., Nikonov S.V., Sedelnikova S.E., Shikaeva O.S., Vasiliev D., Zhdanov A.S., Liljas A., Svensson L.A. Biochimie 74:327-336(1992) [PubMed: 1637860] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-24.
[4]	"Crystal structure of the ribosomal protein S6 from Thermus thermophilus." Lindahl M., Svensson L.A., Liljas A., Sedelnikova S.E., Eliseikina I.A., Fomenkova N.P., Nevskaya N., Nikonov S.V., Garber M.B., Muranova T.A., Rykonova A.I., Amons R. EMBO J. 13:1249-1254(1994) [PubMed: 8137808] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS). Strain: VK1.
[5]	"Structural changes in the transition state of protein folding: alternative interpretations of curved chevron plots." Otzen D.E., Kristensen O., Proctor M., Oliveberg M. Biochemistry 38:6499-6511(1999) [PubMed: 10350468] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.95 ANGSTROMS). Strain: VK1.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AF146075 Genomic DNA. Translation: AAF27295.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1CQM	X-ray	1.65	A/B	1-101	[»]
1CQN	X-ray	2.10	A/B	1-101	[»]
1EG0	electron microscopy	11.50	C	1-97	[»]
1LOU	X-ray	1.95	A	1-101	[»]
1QJH	X-ray	2.20	A	1-101	[»]
1RIS	X-ray	2.00	A	1-101	[»]
1TWT	model	-	I	1-101	[»]
2BVZ	X-ray	2.20	A	1-101	[»]
2BXJ	X-ray	2.40	A/B	1-101	[»]
3ZZP	X-ray	0.96	A	3-91	[»]

ProteinModelPortal

P23370.

SMR

P23370. Positions 1-101.

ModBase

Search...

Protein-protein interaction databases

DIP

DIP-6173N.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Family and domain databases

HAMAP

MF_00360. Ribosomal_S6.
[Tree]

InterPro

IPR000529. Ribosomal_S6.
IPR020815. Ribosomal_S6_CS.
IPR020814. Ribosomal_S6_plastid/chlpt.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
[Graphical view]

Gene3D

G3DSA:3.30.70.60. Transl_elong_EF1B/rib_con. 1 hit.

Pfam

PF01250. Ribosomal_S6. 1 hit.
[Graphical view]

SUPFAM

SSF54995. Ribosomal_S6. 1 hit.

TIGRFAMs

TIGR00166. S6. 1 hit.

PROSITE

PS01048. RIBOSOMAL_S6. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RS6_THETH

Accession

Primary (citable) accession number: P23370

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	April 1, 1993
Last modified:	January 25, 2012
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program