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Protein

54S ribosomal protein L25, mitochondrial

Gene

MRPL25

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD

GO - Biological processi

  • mitochondrial translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-30788-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L25, mitochondrial
Alternative name(s):
YmL25
Gene namesi
Name:MRPL25
Synonyms:YMR26
Ordered Locus Names:YGR076C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome VII

Organism-specific databases

EuPathDBiFungiDB:YGR076C.
SGDiS000003308. MRPL25.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00000876902 – 15754S ribosomal protein L25, mitochondrialAdd BLAST156

Proteomic databases

MaxQBiP23369.
PRIDEiP23369.

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit. Mature mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S subunit contains at least 33 different proteins and 1 molecule of RNA (15S). The 54S subunit contains at least 45 different proteins and 1 molecule of RNA (21S).2 Publications

Protein-protein interaction databases

BioGridi33318. 15 interactors.
DIPiDIP-6803N.
IntActiP23369. 5 interactors.
MINTiMINT-668408.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20b1-157[»]
ProteinModelPortaliP23369.
SMRiP23369.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000189737.
InParanoidiP23369.
KOiK17438.
OMAiKLHNFFI.
OrthoDBiEOG092C5IRE.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P23369-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSYKQYFDSL PLKLKSFFQR YPPSIKYSPV STSTKAINAN PFLPNKHPVT
60 70 80 90 100
QRFHDPKYSL RRMSDVYKLA LRYGVEEFLP PIENTKKLFF EEKYNKKTLM
110 120 130 140 150
KGVLLPKGHK HELKLNEKLK KREEALKKVD ELIASKKGSK YAKRVEKMKK

NQSIGWF
Length:157
Mass (Da):18,587
Last modified:January 23, 2007 - v2
Checksum:iDAB3B47998D6CEEB
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti14L → V AA sequence (PubMed:2017142).Curated1
Sequence conflicti27Y → K AA sequence (PubMed:2017142).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56106 Genomic DNA. Translation: CAA39582.1.
Z72861 Genomic DNA. Translation: CAA97078.1.
BK006941 Genomic DNA. Translation: DAA08169.1.
PIRiS14050.
RefSeqiNP_011590.1. NM_001181205.1.

Genome annotation databases

EnsemblFungiiYGR076C; YGR076C; YGR076C.
GeneIDi852967.
KEGGisce:YGR076C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X56106 Genomic DNA. Translation: CAA39582.1.
Z72861 Genomic DNA. Translation: CAA97078.1.
BK006941 Genomic DNA. Translation: DAA08169.1.
PIRiS14050.
RefSeqiNP_011590.1. NM_001181205.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20b1-157[»]
ProteinModelPortaliP23369.
SMRiP23369.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi33318. 15 interactors.
DIPiDIP-6803N.
IntActiP23369. 5 interactors.
MINTiMINT-668408.

Proteomic databases

MaxQBiP23369.
PRIDEiP23369.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYGR076C; YGR076C; YGR076C.
GeneIDi852967.
KEGGisce:YGR076C.

Organism-specific databases

EuPathDBiFungiDB:YGR076C.
SGDiS000003308. MRPL25.

Phylogenomic databases

HOGENOMiHOG000189737.
InParanoidiP23369.
KOiK17438.
OMAiKLHNFFI.
OrthoDBiEOG092C5IRE.

Enzyme and pathway databases

BioCyciYEAST:G3O-30788-MONOMER.

Miscellaneous databases

PROiP23369.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiRM25_YEAST
AccessioniPrimary (citable) accession number: P23369
Secondary accession number(s): D6VUK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: January 23, 2007
Last modified: November 2, 2016
This is version 130 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1550 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome VII
    Yeast (Saccharomyces cerevisiae) chromosome VII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.