Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

60S ribosomal protein L12

Gene

Rpl12

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Binds directly to 26S ribosomal RNA.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L12
Gene namesi
Name:Rpl12
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi1565106. Rpl12.

Subcellular locationi

GO - Cellular componenti

  • cytosolic large ribosomal subunit Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 16516560S ribosomal protein L12PRO_0000104458Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei38 – 381PhosphoserineBy similarity
Modified residuei54 – 541N6-acetyllysineBy similarity
Modified residuei165 – 1651PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiP23358.
PRIDEiP23358.

PTM databases

iPTMnetiP23358.

Expressioni

Gene expression databases

ExpressionAtlasiP23358. baseline.
GenevisibleiP23358. RN.

Interactioni

Protein-protein interaction databases

IntActiP23358. 2 interactions.
MINTiMINT-4571063.
STRINGi10116.ENSRNOP00000041462.

Structurei

3D structure databases

ProteinModelPortaliP23358.
SMRiP23358. Positions 2-144.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L11P family.Curated

Phylogenomic databases

eggNOGiKOG0886. Eukaryota.
COG0080. LUCA.
GeneTreeiENSGT00390000006922.
HOGENOMiHOG000082125.
HOVERGENiHBG007231.
InParanoidiP23358.
KOiK02870.
OMAiAYSVGCQ.
OrthoDBiEOG7JMGG9.
PhylomeDBiP23358.
TreeFamiTF300123.

Family and domain databases

Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11.
InterProiIPR000911. Ribosomal_L11/L12.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTiSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23358-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKFDPNEI KVVYLRCTGG EVGATSALAP KIGPLGLSPK KVGDDIAKAT
60 70 80 90 100
GDWKGLRITV KLTIQNRQAQ IEVVPSASAL IIKALKEPPR DRKKQKNIKH
110 120 130 140 150
NGNITFDEIV NIARQMRHRS LARELSGTIK EILGTAQSVG CNVDGRHPHD
160
IIDDINSGAV ECPAS
Length:165
Mass (Da):17,846
Last modified:November 1, 1991 - v1
Checksum:i6F1C882B6F2350F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53504 mRNA. Translation: CAA37581.1.
PIRiA36667. R7RT12.
RefSeqiNP_001102668.1. NM_001109198.1.
XP_006227318.1. XM_006227256.2.
XP_006256697.1. XM_006256635.2.
UniGeneiRn.128979.
Rn.203094.
Rn.203151.

Genome annotation databases

EnsembliENSRNOT00000042736; ENSRNOP00000041462; ENSRNOG00000028993.
GeneIDi102555453.
499782.
KEGGirno:102555453.
rno:499782.
UCSCiRGD:1565106. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53504 mRNA. Translation: CAA37581.1.
PIRiA36667. R7RT12.
RefSeqiNP_001102668.1. NM_001109198.1.
XP_006227318.1. XM_006227256.2.
XP_006256697.1. XM_006256635.2.
UniGeneiRn.128979.
Rn.203094.
Rn.203151.

3D structure databases

ProteinModelPortaliP23358.
SMRiP23358. Positions 2-144.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP23358. 2 interactions.
MINTiMINT-4571063.
STRINGi10116.ENSRNOP00000041462.

PTM databases

iPTMnetiP23358.

Proteomic databases

PaxDbiP23358.
PRIDEiP23358.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000042736; ENSRNOP00000041462; ENSRNOG00000028993.
GeneIDi102555453.
499782.
KEGGirno:102555453.
rno:499782.
UCSCiRGD:1565106. rat.

Organism-specific databases

CTDi6136.
RGDi1565106. Rpl12.

Phylogenomic databases

eggNOGiKOG0886. Eukaryota.
COG0080. LUCA.
GeneTreeiENSGT00390000006922.
HOGENOMiHOG000082125.
HOVERGENiHBG007231.
InParanoidiP23358.
KOiK02870.
OMAiAYSVGCQ.
OrthoDBiEOG7JMGG9.
PhylomeDBiP23358.
TreeFamiTF300123.

Miscellaneous databases

PROiP23358.

Gene expression databases

ExpressionAtlasiP23358. baseline.
GenevisibleiP23358. RN.

Family and domain databases

Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11.
InterProiIPR000911. Ribosomal_L11/L12.
IPR020783. Ribosomal_L11_C.
IPR020785. Ribosomal_L11_CS.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTiSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
PROSITEiPS00359. RIBOSOMAL_L11. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The primary structure of rat ribosomal protein L12."
    Suzuki K., Olvera J., Wool I.G.
    Biochem. Biophys. Res. Commun. 172:35-41(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: Sprague-Dawley.
    Tissue: Liver.

Entry informationi

Entry nameiRL12_RAT
AccessioniPrimary (citable) accession number: P23358
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: July 6, 2016
This is version 127 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.