P23349 (RL7_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L7/L12

Gene names

Name:	rplL
Synonyms:	rpl12
Ordered Locus Names:	sll1746

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	128 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation. HAMAP-Rule MF_00368
Sequence similarities	Belongs to the ribosomal protein L7/L12P family.

Ontologies

Keywords
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed Ref.4
	Chain	2 – 128	127	50S ribosomal protein L7/L12 HAMAP-Rule MF_00368		PRO_0000157595

Sequences

	Sequence		Length	Mass (Da)
	P23349 [UniParc]. Last modified January 23, 2007. Version 3. Checksum: FCBF73A205A53946	FASTA	128	13,259
	10 20 30 40 50 60 MSAATDQILE QLKSLSLLEA SELVKQIEEA FGVSAAAPVG GMVMAAAAAA PAEAAEEKTE 70 80 90 100 110 120 FDVILEEVPA DKKIAVLKVV RTITGLGLKE AKELVESTPK AIKEATGKDD AEAIKKQIEE AGGKAAVK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning and characterization of the genes for ribosomal proteins L10 and L12 from Synechocystis Sp. PCC 6803: comparison of gene clustering pattern and protein sequence homology between cyanobacteria and chloroplasts." Sibold C., Subramanian A.R. Biochim. Biophys. Acta 1050:61-68(1990) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.
[3]	"A novel operon organization involving the genes for chorismate synthase (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11, L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803." Schmidt J., Bubunenko M., Subramanian A.R. J. Biol. Chem. 268:27447-27457(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 117-128.
[4]	"Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes." Sazuka T., Ohara O. Electrophoresis 18:1252-1258(1997) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 2-8.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X53178 Genomic DNA. Translation: CAA37318.1. BA000022 Genomic DNA. Translation: BAA17416.1. X67516 Genomic DNA. Translation: CAA47854.1.
PIR	S13069.
RefSeq	NP_440736.1. NC_000911.1. YP_005650795.1. NC_017277.1. YP_007450619.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P23349.
SMR	P23349. Positions 54-128.
ModBase	Search...
Protein-protein interaction databases
IntAct	P23349. 1 interaction.
STRING	1148.sll1746.
Proteomic databases
PaxDb	P23349.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA17416; BAA17416; BAA17416.
GeneID	12254717. 14616269. 954039.
KEGG	syn:sll1746. syy:SYNGTS_0842.
PATRIC	23838690. VBISynSp132158_0912.
Phylogenomic databases
eggNOG	COG0222.
HOGENOM	HOG000248813.
KO	K02935.
OMA	MADLKDF.
ProtClustDB	PRK00157.
Family and domain databases
Gene3D	3.30.1390.10. 1 hit.
HAMAP	MF_00368. Ribosomal_L7_L12.
InterPro	IPR000206. Ribosomal_L7/12. IPR014719. Ribosomal_L7/12_C/ClpS-like. IPR013823. Ribosomal_L7/L12_C. IPR008932. Ribosomal_L7/L12_oligo. [Graphical view]
Pfam	PF00542. Ribosomal_L12. 1 hit. [Graphical view]
ProDom	PD001326. Ribosomal_L7/L12_C. 1 hit. [Graphical view] [Entries sharing at least one domain]
SUPFAM	SSF48300. Ribosomal_L12/7. 1 hit. SSF54736. Ribosomal_L7/12_C/ClpS-like. 1 hit.
TIGRFAMs	TIGR00855. L12. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RL7_SYNY3

Accession

Primary (citable) accession number: P23349

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	January 23, 2007
Last modified:	May 1, 2013
This is version 90 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program