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Protein

50S ribosomal protein L7/L12

Gene

rplL

Organism
Synechocystis sp. (strain PCC 6803 / Kazusa)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.UniRule annotation

GO - Molecular functioni

  1. structural constituent of ribosome Source: InterPro

GO - Biological processi

  1. translation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
50S ribosomal protein L7/L12UniRule annotation
Gene namesi
Name:rplLUniRule annotation
Synonyms:rpl12UniRule annotation
Ordered Locus Names:sll1746
OrganismiSynechocystis sp. (strain PCC 6803 / Kazusa)
Taxonomic identifieri1111708 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis
ProteomesiUP000001425 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. ribosome Source: UniProtKB-KW
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed1 Publication
Chaini2 – 12812750S ribosomal protein L7/L12PRO_0000157595Add
BLAST

Proteomic databases

PaxDbiP23349.

Interactioni

Subunit structurei

Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.UniRule annotation

Protein-protein interaction databases

IntActiP23349. 1 interaction.
STRINGi1148.sll1746.

Structurei

3D structure databases

ProteinModelPortaliP23349.
SMRiP23349. Positions 54-128.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L7/L12P family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0222.
HOGENOMiHOG000248813.
InParanoidiP23349.
KOiK02935.
OMAiLEDKWGV.
OrthoDBiEOG6WMJ69.
PhylomeDBiP23349.

Family and domain databases

Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERiPTHR11809. PTHR11809. 1 hit.
PfamiPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P23349-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAATDQILE QLKSLSLLEA SELVKQIEEA FGVSAAAPVG GMVMAAAAAA
60 70 80 90 100
PAEAAEEKTE FDVILEEVPA DKKIAVLKVV RTITGLGLKE AKELVESTPK
110 120
AIKEATGKDD AEAIKKQIEE AGGKAAVK
Length:128
Mass (Da):13,259
Last modified:January 22, 2007 - v3
Checksum:iFCBF73A205A53946
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53178 Genomic DNA. Translation: CAA37318.1.
BA000022 Genomic DNA. Translation: BAA17416.1.
X67516 Genomic DNA. Translation: CAA47854.1.
PIRiS13069.
RefSeqiNP_440736.1. NC_000911.1.
YP_005650795.1. NC_017277.1.
YP_007450619.1. NC_020286.1.

Genome annotation databases

EnsemblBacteriaiBAA17416; BAA17416; BAA17416.
KEGGisyn:sll1746.
PATRICi23838690. VBISynSp132158_0912.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X53178 Genomic DNA. Translation: CAA37318.1.
BA000022 Genomic DNA. Translation: BAA17416.1.
X67516 Genomic DNA. Translation: CAA47854.1.
PIRiS13069.
RefSeqiNP_440736.1. NC_000911.1.
YP_005650795.1. NC_017277.1.
YP_007450619.1. NC_020286.1.

3D structure databases

ProteinModelPortaliP23349.
SMRiP23349. Positions 54-128.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiP23349. 1 interaction.
STRINGi1148.sll1746.

Proteomic databases

PaxDbiP23349.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAA17416; BAA17416; BAA17416.
KEGGisyn:sll1746.
PATRICi23838690. VBISynSp132158_0912.

Phylogenomic databases

eggNOGiCOG0222.
HOGENOMiHOG000248813.
InParanoidiP23349.
KOiK02935.
OMAiLEDKWGV.
OrthoDBiEOG6WMJ69.
PhylomeDBiP23349.

Family and domain databases

Gene3Di3.30.1390.10. 1 hit.
HAMAPiMF_00368. Ribosomal_L7_L12.
InterProiIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERiPTHR11809. PTHR11809. 1 hit.
PfamiPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomiPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMiSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsiTIGR00855. L12. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of the genes for ribosomal proteins L10 and L12 from Synechocystis Sp. PCC 6803: comparison of gene clustering pattern and protein sequence homology between cyanobacteria and chloroplasts."
    Sibold C., Subramanian A.R.
    Biochim. Biophys. Acta 1050:61-68(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
    Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.
    , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
    DNA Res. 3:109-136(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: PCC 6803 / Kazusa.
  3. "A novel operon organization involving the genes for chorismate synthase (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11, L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803."
    Schmidt J., Bubunenko M., Subramanian A.R.
    J. Biol. Chem. 268:27447-27457(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 117-128.
  4. "Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes."
    Sazuka T., Ohara O.
    Electrophoresis 18:1252-1258(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: PROTEIN SEQUENCE OF 2-8.

Entry informationi

Entry nameiRL7_SYNY3
AccessioniPrimary (citable) accession number: P23349
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1991
Last sequence update: January 22, 2007
Last modified: March 31, 2015
This is version 105 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Ribosomal proteins
    Ribosomal proteins families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families
  3. Synechocystis PCC 6803
    Synechocystis (strain PCC 6803): entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.