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P23349 (RL7_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 100. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
50S ribosomal protein L7/L12
Gene names
Name:rplL
Synonyms:rpl12
Ordered Locus Names:sll1746
OrganismSynechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]
Taxonomic identifier1111708 [NCBI]
Taxonomic lineageBacteriaCyanobacteriaOscillatoriophycideaeChroococcalesSynechocystis

Protein attributes

Sequence length128 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation By similarity. HAMAP-Rule MF_00368

Subunit structure

Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors By similarity.

Sequence similarities

Belongs to the ribosomal protein L7/L12P family.

Ontologies

Keywords
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical termComplete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Biological_processtranslation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.4
Chain2 – 12812750S ribosomal protein L7/L12 HAMAP-Rule MF_00368
PRO_0000157595

Sequences

Sequence LengthMass (Da)Tools
P23349 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: FCBF73A205A53946

FASTA12813,259
        10         20         30         40         50         60 
MSAATDQILE QLKSLSLLEA SELVKQIEEA FGVSAAAPVG GMVMAAAAAA PAEAAEEKTE 

        70         80         90        100        110        120 
FDVILEEVPA DKKIAVLKVV RTITGLGLKE AKELVESTPK AIKEATGKDD AEAIKKQIEE 


AGGKAAVK 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterization of the genes for ribosomal proteins L10 and L12 from Synechocystis Sp. PCC 6803: comparison of gene clustering pattern and protein sequence homology between cyanobacteria and chloroplasts."
Sibold C., Subramanian A.R.
Biochim. Biophys. Acta 1050:61-68(1990) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions."
Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. expand/collapse author list , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.
DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: PCC 6803 / Kazusa.
[3]"A novel operon organization involving the genes for chorismate synthase (aromatic biosynthesis pathway) and ribosomal GTPase center proteins (L11, L1, L10, L12: rplKAJL) in cyanobacterium Synechocystis PCC 6803."
Schmidt J., Bubunenko M., Subramanian A.R.
J. Biol. Chem. 268:27447-27457(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 117-128.
[4]"Towards a proteome project of cyanobacterium Synechocystis sp. strain PCC6803: linking 130 protein spots with their respective genes."
Sazuka T., Ohara O.
Electrophoresis 18:1252-1258(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-8.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X53178 Genomic DNA. Translation: CAA37318.1.
BA000022 Genomic DNA. Translation: BAA17416.1.
X67516 Genomic DNA. Translation: CAA47854.1.
PIRS13069.
RefSeqNP_440736.1. NC_000911.1.
YP_005650795.1. NC_017277.1.
YP_007450619.1. NC_020286.1.

3D structure databases

ProteinModelPortalP23349.
SMRP23349. Positions 54-128.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActP23349. 1 interaction.
STRING1148.sll1746.

Proteomic databases

PaxDbP23349.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAA17416; BAA17416; BAA17416.
GeneID954039.
KEGGsyn:sll1746.
syy:SYNGTS_0842.
syz:MYO_18470.
PATRIC23838690. VBISynSp132158_0912.

Phylogenomic databases

eggNOGCOG0222.
HOGENOMHOG000248813.
KOK02935.
OMAEFISNMT.
OrthoDBEOG6WMJ69.
PhylomeDBP23349.

Family and domain databases

Gene3D3.30.1390.10. 1 hit.
HAMAPMF_00368. Ribosomal_L7_L12.
InterProIPR000206. Ribosomal_L7/12.
IPR014719. Ribosomal_L7/12_C/ClpS-like.
IPR013823. Ribosomal_L7/L12_C.
IPR008932. Ribosomal_L7/L12_oligo.
[Graphical view]
PANTHERPTHR11809. PTHR11809. 1 hit.
PfamPF00542. Ribosomal_L12. 1 hit.
[Graphical view]
ProDomPD001326. Ribosomal_L7/L12_C. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SUPFAMSSF48300. SSF48300. 1 hit.
SSF54736. SSF54736. 1 hit.
TIGRFAMsTIGR00855. L12. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRL7_SYNY3
AccessionPrimary (citable) accession number: P23349
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: January 23, 2007
Last modified: July 9, 2014
This is version 100 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Synechocystis PCC 6803

Synechocystis (strain PCC 6803): entries and gene names

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries