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P23325

- ARPA_ECOLI

UniProt

P23325 - ARPA_ECOLI

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Protein
Ankyrin repeat protein A
Gene
arpA, arp, yjaC, b4017, JW3977
Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 2 out of 5 - Protein predictedi

Functioni

Enzyme and pathway databases

BioCyciEcoCyc:EG11208-MONOMER.
ECOL316407:JW3977-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ankyrin repeat protein A
Alternative name(s):
Ankyrin-like regulatory protein
Gene namesi
Name:arpA
Synonyms:arp, yjaC
Ordered Locus Names:b4017, JW3977
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

Organism-specific databases

EcoGeneiEG11208. arpA.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 728728Ankyrin repeat protein A
PRO_0000067228Add
BLAST

Proteomic databases

PaxDbiP23325.
PRIDEiP23325.

Expressioni

Gene expression databases

GenevestigatoriP23325.

Interactioni

Protein-protein interaction databases

DIPiDIP-9159N.
IntActiP23325. 7 interactions.
STRINGi511145.b4017.

Structurei

3D structure databases

ProteinModelPortaliP23325.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati381 – 41030ANK 1
Add
BLAST
Repeati429 – 45830ANK 2
Add
BLAST
Repeati477 – 50630ANK 3
Add
BLAST
Repeati525 – 55430ANK 4
Add
BLAST
Repeati573 – 60230ANK 5
Add
BLAST

Sequence similaritiesi

Contains 5 ANK repeats.

Keywords - Domaini

ANK repeat, Repeat

Phylogenomic databases

eggNOGiCOG0666.
HOGENOMiHOG000009667.
KOiK06867.
OMAiILEALPC.
OrthoDBiEOG628F1T.

Family and domain databases

Gene3Di1.25.40.20. 1 hit.
InterProiIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR012927. Toxin_15_N.
[Graphical view]
PfamiPF07906. Toxin_15. 1 hit.
[Graphical view]
SMARTiSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMiSSF48403. SSF48403. 1 hit.

Sequencei

Sequence statusi: Complete.

P23325-1 [UniParc]FASTAAdd to Basket

« Hide

MITRIPRSSF SANINNTAQT NEHQTLSELF YKELEDKFSG KELATPLLKS    50
FSENCRQNGR HIFSNKDFVI KFSTSVLQAD KKEITIINKN ENTTLTQTIA 100
PIFEKYLMEI LPQRSDTLDK QELNLKSDRK EKEFPRIKLN GQCYFPGRPQ 150
NRIVCRHIAA QYINDIYQNV DYKPHQDDYS SAEKFLTHFN KKCKNQTLAL 200
VSSRPEGRCV AACGDFGLVM KAYFDKMESN GISVMAAILL VDNHALTVRL 250
RIKNTTEGCT HYVVSVYDPN VTNDKIRIMS ESKENIKHYS LMDFMNVDYS 300
LLKWSNDHVI NQSVAIIPAL PKEQLLMLKG SVDEITPPLS PATMNLLMAI 350
GQNHQLTQLM IQLQKMPELH RTEMLTAYNS INLPGLYLAI NYGNADIVET 400
IFNSLSETGY EGLLSKKNLM HILEAKDKNG FSGLFLAISR KDKNVVTSIL 450
NALPKLAATH HLDNEQVYKF LSAKNRTSSH VLYHVMANGD ADMLKIVLNA 500
LPLLIRTCHL TKEQVLDLLK AKDFYGCPGL YLAMQNGHSD IVKVILEALP 550
SLAQEINISA SDIVDLLTAK SLARDTGLFM AMQRGHMNVI NTIFNALPTL 600
FNTFKFDKKN MKPLLLANNS NEYPGLFSAI QHKQQNVVET VYLALSDHAR 650
LFGFTAEDIM DFWQHKAPQK YSAFELAFEF GHRVIAELIL NTLNKMAESF 700
GFTDNPRYIA EKNYMEALLK KASPHTVR 728
Length:728
Mass (Da):82,598
Last modified:July 19, 2003 - v3
Checksum:i19EE240C4561B3F0
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti124 – 1241N → D in AAA73004. 1 Publication
Sequence conflicti282 – 2821S → T in AAA73004. 1 Publication
Sequence conflicti701 – 72828GFTDN…PHTVR → TQKSISPYRTLNLCLRRYA in AAA73004. 1 Publication
Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00006 Genomic DNA. Translation: AAC43111.1.
U00096 Genomic DNA. Translation: AAC76987.1.
AP009048 Genomic DNA. Translation: BAE78019.1.
M63497 Genomic DNA. Translation: AAA73004.1.
PIRiH65208.
RefSeqiNP_418441.1. NC_000913.3.
YP_492160.1. NC_007779.1.

Genome annotation databases

EnsemblBacteriaiAAC76987; AAC76987; b4017.
BAE78019; BAE78019; BAE78019.
GeneIDi12933010.
944933.
KEGGiecj:Y75_p3904.
eco:b4017.
PATRICi32123563. VBIEscCol129921_4130.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U00006 Genomic DNA. Translation: AAC43111.1 .
U00096 Genomic DNA. Translation: AAC76987.1 .
AP009048 Genomic DNA. Translation: BAE78019.1 .
M63497 Genomic DNA. Translation: AAA73004.1 .
PIRi H65208.
RefSeqi NP_418441.1. NC_000913.3.
YP_492160.1. NC_007779.1.

3D structure databases

ProteinModelPortali P23325.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

DIPi DIP-9159N.
IntActi P23325. 7 interactions.
STRINGi 511145.b4017.

Proteomic databases

PaxDbi P23325.
PRIDEi P23325.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAC76987 ; AAC76987 ; b4017 .
BAE78019 ; BAE78019 ; BAE78019 .
GeneIDi 12933010.
944933.
KEGGi ecj:Y75_p3904.
eco:b4017.
PATRICi 32123563. VBIEscCol129921_4130.

Organism-specific databases

EchoBASEi EB1193.
EcoGenei EG11208. arpA.

Phylogenomic databases

eggNOGi COG0666.
HOGENOMi HOG000009667.
KOi K06867.
OMAi ILEALPC.
OrthoDBi EOG628F1T.

Enzyme and pathway databases

BioCyci EcoCyc:EG11208-MONOMER.
ECOL316407:JW3977-MONOMER.

Miscellaneous databases

PROi P23325.

Gene expression databases

Genevestigatori P23325.

Family and domain databases

Gene3Di 1.25.40.20. 1 hit.
InterProi IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR012927. Toxin_15_N.
[Graphical view ]
Pfami PF07906. Toxin_15. 1 hit.
[Graphical view ]
SMARTi SM00248. ANK. 6 hits.
[Graphical view ]
SUPFAMi SSF48403. SSF48403. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes."
    Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.
    Nucleic Acids Res. 21:5408-5417(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 282.
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "Primary structure of the intergenic region between aceK and iclR in the Escherichia coli chromosome."
    Galinier A., Bleicher F., Negre D., Perriere G., Duclos B., Cozzone A.J., Cortay J.-C.
    Gene 97:149-150(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 108-728.
  5. "Detecting patterns in protein sequences."
    Neuwald A.F., Green P.
    J. Mol. Biol. 239:698-712(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION OF ANKYRIN REPEATS.

Entry informationi

Entry nameiARPA_ECOLI
AccessioniPrimary (citable) accession number: P23325
Secondary accession number(s): P76781, Q2M6T7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: July 19, 2003
Last modified: May 14, 2014
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi