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P23325

- ARPA_ECOLI

UniProt

P23325 - ARPA_ECOLI

Protein

Ankyrin repeat protein A

Gene

arpA

Organism
Escherichia coli (strain K12)
Status
Reviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 3 (19 Jul 2003)
      Previous versions | rss
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    Functioni

    Enzyme and pathway databases

    BioCyciEcoCyc:EG11208-MONOMER.
    ECOL316407:JW3977-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ankyrin repeat protein A
    Alternative name(s):
    Ankyrin-like regulatory protein
    Gene namesi
    Name:arpA
    Synonyms:arp, yjaC
    Ordered Locus Names:b4017, JW3977
    OrganismiEscherichia coli (strain K12)
    Taxonomic identifieri83333 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
    ProteomesiUP000000318: Chromosome, UP000000625: Chromosome

    Organism-specific databases

    EcoGeneiEG11208. arpA.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 728728Ankyrin repeat protein APRO_0000067228Add
    BLAST

    Proteomic databases

    PaxDbiP23325.
    PRIDEiP23325.

    Expressioni

    Gene expression databases

    GenevestigatoriP23325.

    Interactioni

    Protein-protein interaction databases

    DIPiDIP-9159N.
    IntActiP23325. 7 interactions.
    STRINGi511145.b4017.

    Structurei

    3D structure databases

    ProteinModelPortaliP23325.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati381 – 41030ANK 11 PublicationAdd
    BLAST
    Repeati429 – 45830ANK 21 PublicationAdd
    BLAST
    Repeati477 – 50630ANK 31 PublicationAdd
    BLAST
    Repeati525 – 55430ANK 41 PublicationAdd
    BLAST
    Repeati573 – 60230ANK 51 PublicationAdd
    BLAST

    Sequence similaritiesi

    Contains 5 ANK repeats.Curated

    Keywords - Domaini

    ANK repeat, Repeat

    Phylogenomic databases

    eggNOGiCOG0666.
    HOGENOMiHOG000009667.
    KOiK06867.
    OMAiILEALPC.
    OrthoDBiEOG628F1T.

    Family and domain databases

    Gene3Di1.25.40.20. 1 hit.
    InterProiIPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR012927. Toxin_15_N.
    [Graphical view]
    PfamiPF07906. Toxin_15. 1 hit.
    [Graphical view]
    SMARTiSM00248. ANK. 6 hits.
    [Graphical view]
    SUPFAMiSSF48403. SSF48403. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P23325-1 [UniParc]FASTAAdd to Basket

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    MITRIPRSSF SANINNTAQT NEHQTLSELF YKELEDKFSG KELATPLLKS    50
    FSENCRQNGR HIFSNKDFVI KFSTSVLQAD KKEITIINKN ENTTLTQTIA 100
    PIFEKYLMEI LPQRSDTLDK QELNLKSDRK EKEFPRIKLN GQCYFPGRPQ 150
    NRIVCRHIAA QYINDIYQNV DYKPHQDDYS SAEKFLTHFN KKCKNQTLAL 200
    VSSRPEGRCV AACGDFGLVM KAYFDKMESN GISVMAAILL VDNHALTVRL 250
    RIKNTTEGCT HYVVSVYDPN VTNDKIRIMS ESKENIKHYS LMDFMNVDYS 300
    LLKWSNDHVI NQSVAIIPAL PKEQLLMLKG SVDEITPPLS PATMNLLMAI 350
    GQNHQLTQLM IQLQKMPELH RTEMLTAYNS INLPGLYLAI NYGNADIVET 400
    IFNSLSETGY EGLLSKKNLM HILEAKDKNG FSGLFLAISR KDKNVVTSIL 450
    NALPKLAATH HLDNEQVYKF LSAKNRTSSH VLYHVMANGD ADMLKIVLNA 500
    LPLLIRTCHL TKEQVLDLLK AKDFYGCPGL YLAMQNGHSD IVKVILEALP 550
    SLAQEINISA SDIVDLLTAK SLARDTGLFM AMQRGHMNVI NTIFNALPTL 600
    FNTFKFDKKN MKPLLLANNS NEYPGLFSAI QHKQQNVVET VYLALSDHAR 650
    LFGFTAEDIM DFWQHKAPQK YSAFELAFEF GHRVIAELIL NTLNKMAESF 700
    GFTDNPRYIA EKNYMEALLK KASPHTVR 728
    Length:728
    Mass (Da):82,598
    Last modified:July 19, 2003 - v3
    Checksum:i19EE240C4561B3F0
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti124 – 1241N → D in AAA73004. (PubMed:1995429)Curated
    Sequence conflicti282 – 2821S → T in AAA73004. (PubMed:1995429)Curated
    Sequence conflicti701 – 72828GFTDN…PHTVR → TQKSISPYRTLNLCLRRYA in AAA73004. (PubMed:1995429)CuratedAdd
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00006 Genomic DNA. Translation: AAC43111.1.
    U00096 Genomic DNA. Translation: AAC76987.1.
    AP009048 Genomic DNA. Translation: BAE78019.1.
    M63497 Genomic DNA. Translation: AAA73004.1.
    PIRiH65208.
    RefSeqiNP_418441.1. NC_000913.3.
    YP_492160.1. NC_007779.1.

    Genome annotation databases

    EnsemblBacteriaiAAC76987; AAC76987; b4017.
    BAE78019; BAE78019; BAE78019.
    GeneIDi12933010.
    944933.
    KEGGiecj:Y75_p3904.
    eco:b4017.
    PATRICi32123563. VBIEscCol129921_4130.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U00006 Genomic DNA. Translation: AAC43111.1 .
    U00096 Genomic DNA. Translation: AAC76987.1 .
    AP009048 Genomic DNA. Translation: BAE78019.1 .
    M63497 Genomic DNA. Translation: AAA73004.1 .
    PIRi H65208.
    RefSeqi NP_418441.1. NC_000913.3.
    YP_492160.1. NC_007779.1.

    3D structure databases

    ProteinModelPortali P23325.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    DIPi DIP-9159N.
    IntActi P23325. 7 interactions.
    STRINGi 511145.b4017.

    Proteomic databases

    PaxDbi P23325.
    PRIDEi P23325.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAC76987 ; AAC76987 ; b4017 .
    BAE78019 ; BAE78019 ; BAE78019 .
    GeneIDi 12933010.
    944933.
    KEGGi ecj:Y75_p3904.
    eco:b4017.
    PATRICi 32123563. VBIEscCol129921_4130.

    Organism-specific databases

    EchoBASEi EB1193.
    EcoGenei EG11208. arpA.

    Phylogenomic databases

    eggNOGi COG0666.
    HOGENOMi HOG000009667.
    KOi K06867.
    OMAi ILEALPC.
    OrthoDBi EOG628F1T.

    Enzyme and pathway databases

    BioCyci EcoCyc:EG11208-MONOMER.
    ECOL316407:JW3977-MONOMER.

    Miscellaneous databases

    PROi P23325.

    Gene expression databases

    Genevestigatori P23325.

    Family and domain databases

    Gene3Di 1.25.40.20. 1 hit.
    InterProi IPR002110. Ankyrin_rpt.
    IPR020683. Ankyrin_rpt-contain_dom.
    IPR012927. Toxin_15_N.
    [Graphical view ]
    Pfami PF07906. Toxin_15. 1 hit.
    [Graphical view ]
    SMARTi SM00248. ANK. 6 hits.
    [Graphical view ]
    SUPFAMi SSF48403. SSF48403. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes."
      Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.
      Nucleic Acids Res. 21:5408-5417(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / MG1655 / ATCC 47076.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 282.
      Strain: K12 / MG1655 / ATCC 47076.
    3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
      Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
      Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
    4. "Primary structure of the intergenic region between aceK and iclR in the Escherichia coli chromosome."
      Galinier A., Bleicher F., Negre D., Perriere G., Duclos B., Cozzone A.J., Cortay J.-C.
      Gene 97:149-150(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 108-728.
    5. "Detecting patterns in protein sequences."
      Neuwald A.F., Green P.
      J. Mol. Biol. 239:698-712(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION OF ANKYRIN REPEATS.

    Entry informationi

    Entry nameiARPA_ECOLI
    AccessioniPrimary (citable) accession number: P23325
    Secondary accession number(s): P76781, Q2M6T7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: July 19, 2003
    Last modified: October 1, 2014
    This is version 110 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Escherichia coli
      Escherichia coli (strain K12): entries and cross-references to EcoGene
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3