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P23325 (ARPA_ECOLI) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 109. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Ankyrin repeat protein A
Alternative name(s):
Ankyrin-like regulatory protein
Gene names
Name:arpA
Synonyms:arp, yjaC
Ordered Locus Names:b4017, JW3977
OrganismEscherichia coli (strain K12) [Reference proteome] [HAMAP]
Taxonomic identifier83333 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

Protein attributes

Sequence length728 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Sequence similarities

Contains 5 ANK repeats.

Ontologies

Keywords
   DomainANK repeat
Repeat
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 728728Ankyrin repeat protein A
PRO_0000067228

Regions

Repeat381 – 41030ANK 1
Repeat429 – 45830ANK 2
Repeat477 – 50630ANK 3
Repeat525 – 55430ANK 4
Repeat573 – 60230ANK 5

Experimental info

Sequence conflict1241N → D in AAA73004. Ref.4
Sequence conflict2821S → T in AAA73004. Ref.4
Sequence conflict701 – 72828GFTDN…PHTVR → TQKSISPYRTLNLCLRRYA in AAA73004. Ref.4

Sequences

Sequence LengthMass (Da)Tools
P23325 [UniParc].

Last modified July 19, 2003. Version 3.
Checksum: 19EE240C4561B3F0

FASTA72882,598
        10         20         30         40         50         60 
MITRIPRSSF SANINNTAQT NEHQTLSELF YKELEDKFSG KELATPLLKS FSENCRQNGR 

        70         80         90        100        110        120 
HIFSNKDFVI KFSTSVLQAD KKEITIINKN ENTTLTQTIA PIFEKYLMEI LPQRSDTLDK 

       130        140        150        160        170        180 
QELNLKSDRK EKEFPRIKLN GQCYFPGRPQ NRIVCRHIAA QYINDIYQNV DYKPHQDDYS 

       190        200        210        220        230        240 
SAEKFLTHFN KKCKNQTLAL VSSRPEGRCV AACGDFGLVM KAYFDKMESN GISVMAAILL 

       250        260        270        280        290        300 
VDNHALTVRL RIKNTTEGCT HYVVSVYDPN VTNDKIRIMS ESKENIKHYS LMDFMNVDYS 

       310        320        330        340        350        360 
LLKWSNDHVI NQSVAIIPAL PKEQLLMLKG SVDEITPPLS PATMNLLMAI GQNHQLTQLM 

       370        380        390        400        410        420 
IQLQKMPELH RTEMLTAYNS INLPGLYLAI NYGNADIVET IFNSLSETGY EGLLSKKNLM 

       430        440        450        460        470        480 
HILEAKDKNG FSGLFLAISR KDKNVVTSIL NALPKLAATH HLDNEQVYKF LSAKNRTSSH 

       490        500        510        520        530        540 
VLYHVMANGD ADMLKIVLNA LPLLIRTCHL TKEQVLDLLK AKDFYGCPGL YLAMQNGHSD 

       550        560        570        580        590        600 
IVKVILEALP SLAQEINISA SDIVDLLTAK SLARDTGLFM AMQRGHMNVI NTIFNALPTL 

       610        620        630        640        650        660 
FNTFKFDKKN MKPLLLANNS NEYPGLFSAI QHKQQNVVET VYLALSDHAR LFGFTAEDIM 

       670        680        690        700        710        720 
DFWQHKAPQK YSAFELAFEF GHRVIAELIL NTLNKMAESF GFTDNPRYIA EKNYMEALLK 


KASPHTVR 

« Hide

References

« Hide 'large scale' references
[1]"Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes."
Blattner F.R., Burland V.D., Plunkett G. III, Sofia H.J., Daniels D.L.
Nucleic Acids Res. 21:5408-5417(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / MG1655 / ATCC 47076.
[2]"The complete genome sequence of Escherichia coli K-12."
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.
Science 277:1453-1462(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], SEQUENCE REVISION TO 282.
Strain: K12 / MG1655 / ATCC 47076.
[3]"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
[4]"Primary structure of the intergenic region between aceK and iclR in the Escherichia coli chromosome."
Galinier A., Bleicher F., Negre D., Perriere G., Duclos B., Cozzone A.J., Cortay J.-C.
Gene 97:149-150(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 108-728.
[5]"Detecting patterns in protein sequences."
Neuwald A.F., Green P.
J. Mol. Biol. 239:698-712(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: IDENTIFICATION OF ANKYRIN REPEATS.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U00006 Genomic DNA. Translation: AAC43111.1.
U00096 Genomic DNA. Translation: AAC76987.1.
AP009048 Genomic DNA. Translation: BAE78019.1.
M63497 Genomic DNA. Translation: AAA73004.1.
PIRH65208.
RefSeqNP_418441.1. NC_000913.3.
YP_492160.1. NC_007779.1.

3D structure databases

ProteinModelPortalP23325.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

DIPDIP-9159N.
IntActP23325. 7 interactions.
STRING511145.b4017.

Proteomic databases

PaxDbP23325.
PRIDEP23325.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAC76987; AAC76987; b4017.
BAE78019; BAE78019; BAE78019.
GeneID12933010.
944933.
KEGGecj:Y75_p3904.
eco:b4017.
PATRIC32123563. VBIEscCol129921_4130.

Organism-specific databases

EchoBASEEB1193.
EcoGeneEG11208. arpA.

Phylogenomic databases

eggNOGCOG0666.
HOGENOMHOG000009667.
KOK06867.
OMAILEALPC.
OrthoDBEOG628F1T.

Enzyme and pathway databases

BioCycEcoCyc:EG11208-MONOMER.
ECOL316407:JW3977-MONOMER.

Gene expression databases

GenevestigatorP23325.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR012927. Toxin_15_N.
[Graphical view]
PfamPF07906. Toxin_15. 1 hit.
[Graphical view]
SMARTSM00248. ANK. 6 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
ProtoNetSearch...

Other

PROP23325.

Entry information

Entry nameARPA_ECOLI
AccessionPrimary (citable) accession number: P23325
Secondary accession number(s): P76781, Q2M6T7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: July 19, 2003
Last modified: May 14, 2014
This is version 109 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Escherichia coli

Escherichia coli (strain K12): entries and cross-references to EcoGene