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P23276

- KELL_HUMAN

UniProt

P23276 - KELL_HUMAN

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Protein
Kell blood group glycoprotein
Gene
KEL
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Zinc endopeptidase with endothelin-3-converting enzyme activity. Cleaves EDN1, EDN2 and EDN3, with a marked preference for EDN3.1 Publication

Cofactori

Binds 1 zinc ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi581 – 5811Zinc; catalytic By similarity
Active sitei582 – 5821
Metal bindingi585 – 5851Zinc; catalytic By similarity
Metal bindingi634 – 6341Zinc; catalytic By similarity
Active sitei638 – 6381Proton donor By similarity

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. metalloendopeptidase activity Source: HGNC
  3. protein binding Source: HGNC

GO - Biological processi

  1. vasoconstriction Source: HGNC
Complete GO annotation...

Keywords - Molecular functioni

Blood group antigen, Hydrolase, Metalloprotease, Protease

Keywords - Ligandi

Metal-binding, Zinc

Protein family/group databases

MEROPSiM13.090.

Names & Taxonomyi

Protein namesi
Recommended name:
Kell blood group glycoprotein (EC:3.4.24.-)
Alternative name(s):
CD_antigen: CD238
Gene namesi
Name:KEL
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 7

Organism-specific databases

HGNCiHGNC:6308. KEL.

Subcellular locationi

Cell membrane; Single-pass type II membrane protein
Note: Spans the erythrocyte membrane, and is attached to the underlying cytoskeleton.

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 4747Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei48 – 6720Helical; Signal-anchor for type II membrane protein; Reviewed prediction
Add
BLAST
Topological domaini68 – 732665Extracellular Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: HGNC
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Mutagenesisi72 – 721C → S: Loss of Kell-XK complex. 1 Publication
Mutagenesisi319 – 3191C → S: No loss of Kell-XK complex. 1 Publication
Mutagenesisi582 – 5821E → G: Loss of catalytic activity. 1 Publication

Organism-specific databases

MIMi110900. phenotype.
Orphaneti157938. Joker disease.
PharmGKBiPA30087.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 732732Kell blood group glycoprotein
PRO_0000078227Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi72 – 72Interchain (with C-347 in XK)1 Publication
Glycosylationi94 – 941N-linked (GlcNAc...) Reviewed prediction
Glycosylationi115 – 1151N-linked (GlcNAc...) Reviewed prediction
Glycosylationi191 – 1911N-linked (GlcNAc...); in KEL2 antigen
Glycosylationi345 – 3451N-linked (GlcNAc...) Reviewed prediction
Glycosylationi627 – 6271N-linked (GlcNAc...) Reviewed prediction

Post-translational modificationi

N-glycosylated.1 Publication

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

MaxQBiP23276.
PaxDbiP23276.
PRIDEiP23276.

PTM databases

PhosphoSiteiP23276.

Expressioni

Tissue specificityi

Expressed at high levels in erythrocytes and testis (in Sertoli cells), and, at lower levels, in skeletal muscle, tonsils (in follicular dendritic cells), lymph node, spleen and appendix (at protein level). Also expressed in many adult and fetal nonerythroid tissues, including brain, spleen, lymph nodes and bone marrow.2 Publications

Gene expression databases

ArrayExpressiP23276.
BgeeiP23276.
CleanExiHS_KEL.
GenevestigatoriP23276.

Organism-specific databases

HPAiHPA042391.

Interactioni

Subunit structurei

Heterodimer with XK; disulfide-linked.1 Publication

Protein-protein interaction databases

BioGridi109993. 4 interactions.
IntActiP23276. 2 interactions.
MINTiMINT-1464824.
STRINGi9606.ENSP00000347409.

Structurei

3D structure databases

ProteinModelPortaliP23276.
SMRiP23276. Positions 313-732.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M13 family.

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG3590.
HOGENOMiHOG000245574.
HOVERGENiHBG002194.
InParanoidiP23276.
KOiK06577.
OMAiSYAQVMC.
PhylomeDBiP23276.
TreeFamiTF315192.

Family and domain databases

InterProiIPR000718. Peptidase_M13.
IPR018497. Peptidase_M13_C.
IPR008753. Peptidase_M13_N.
[Graphical view]
PANTHERiPTHR11733. PTHR11733. 1 hit.
PfamiPF01431. Peptidase_M13. 1 hit.
PF05649. Peptidase_M13_N. 1 hit.
[Graphical view]
PRINTSiPR00786. NEPRILYSIN.
PROSITEiPS00142. ZINC_PROTEASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23276-1 [UniParc]FASTAAdd to Basket

« Hide

MEGGDQSEEE PRERSQAGGM GTLWSQESTP EERLPVEGSR PWAVARRVLT    50
AILILGLLLC FSVLLFYNFQ NCGPRPCETS VCLDLRDHYL ASGNTSVAPC 100
TDFFSFACGR AKETNNSFQE LATKNKNRLR RILEVQNSWH PGSGEEKAFQ 150
FYNSCMDTLA IEAAGTGPLR QVIEELGGWR ISGKWTSLNF NRTLRLLMSQ 200
YGHFPFFRAY LGPHPASPHT PVIQIDQPEF DVPLKQDQEQ KIYAQIFREY 250
LTYLNQLGTL LGGDPSKVQE HSSLSISITS RLFQFLRPLE QRRAQGKLFQ 300
MVTIDQLKEM APAIDWLSCL QATFTPMSLS PSQSLVVHDV EYLKNMSQLV 350
EEMLLKQRDF LQSHMILGLV VTLSPALDSQ FQEARRKLSQ KLRELTEQPP 400
MPARPRWMKC VEETGTFFEP TLAALFVREA FGPSTRSAAM KLFTAIRDAL 450
ITRLRNLPWM NEETQNMAQD KVAQLQVEMG ASEWALKPEL ARQEYNDIQL 500
GSSFLQSVLS CVRSLRARIV QSFLQPHPQH RWKVSPWDVN AYYSVSDHVV 550
VFPAGLLQPP FFHPGYPRAV NFGAAGSIMA HELLHIFYQL LLPGGCLACD 600
NHALQEAHLC LKRHYAAFPL PSRTSFNDSL TFLENAADVG GLAIALQAYS 650
KRLLRHHGET VLPSLDLSPQ QIFFRSYAQV MCRKPSPQDS HDTHSPPHLR 700
VHGPLSSTPA FARYFRCARG ALLNPSSRCQ LW 732
Length:732
Mass (Da):82,824
Last modified:February 1, 1996 - v2
Checksum:i604A168AD300EDB4
GO

Polymorphismi

KEL is responsible for the Kell blood group system. The molecular basis of the K=KEL1/k=KEL2 blood group antigens is a single variation in position 193; Thr-193 corresponds to KEL2 and Met-193 to KEL1. The molecular basis of the Kpa=KEL3/Kpb=KEL4/Kpc=KEL21 blood group antigens is a single variation in position 281; Arg-281 corresponds to KEL4, Trp-281 to KEL3 and Gln-281 to KEL21. The molecular basis of the Jsa=KEL6/Jsb=KEL7 blood group antigens is a single variation in position 597; Leu-597 corresponds to KEL7 and Pro-597 to KEL6. The molecular basis of the KEL11/KEL17 blood group antigens is a single variation in position 302; Val-302 corresponds to KEL11 and Ala-302 to KEL17. The molecular basis of the KEL14/KEL24 blood group antigens is a single variation in position 180; Arg-180 corresponds to KEL14 and Pro-180 to KEL24.

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti163 – 1631A → T.1 Publication
Corresponds to variant rs8175974 [ dbSNP | Ensembl ].
VAR_016265
Natural varianti180 – 1801R → P in KEL24 antigen.
VAR_006731
Natural varianti193 – 1931T → M in KEL1/K antigen. 2 Publications
Corresponds to variant rs8176058 [ dbSNP | Ensembl ].
VAR_006732
Natural varianti248 – 2481R → Q in KEL25 antigen.
VAR_015120
Natural varianti249 – 2491E → K in KEL27 antigen.
VAR_015121
Natural varianti281 – 2811R → Q in KEL21/Kp(c) antigen.
VAR_006734
Natural varianti281 – 2811R → W in KEL3/Kp(a) antigen. 1 Publication
Corresponds to variant rs8176059 [ dbSNP | Ensembl ].
VAR_006733
Natural varianti302 – 3021V → A in KEL17 antigen.
Corresponds to variant rs61729034 [ dbSNP | Ensembl ].
VAR_006735
Natural varianti322 – 3221A → V in KEL22 antigen.
VAR_015122
Natural varianti382 – 3821Q → R in KEL23 antigen.
VAR_015123
Natural varianti406 – 4061R → Q in KEL26 antigen.
VAR_015124
Natural varianti492 – 4921R → Q in KEL19 antigen.
Corresponds to variant rs61729035 [ dbSNP | Ensembl ].
VAR_015125
Natural varianti494 – 4941E → V in KEL10/Ul(a) antigen.
Corresponds to variant rs61729032 [ dbSNP | Ensembl ].
VAR_006736
Natural varianti548 – 5481H → R in KEL12 antigen.
VAR_015126
Natural varianti597 – 5971L → P in KEL6/Js(a) antigen. 1 Publication
Corresponds to variant rs8176038 [ dbSNP | Ensembl ].
VAR_006737
Natural varianti726 – 7261S → A.1 Publication
Corresponds to variant rs8176048 [ dbSNP | Ensembl ].
VAR_016266

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64934 mRNA. Translation: AAA03192.1.
AF172627
, AF172609, AF172610, AF172611, AF172612, AF172613, AF172614, AF172615, AF172616, AF172617, AF172618, AF172619, AF172620, AF172621, AF172622, AF172623, AF172624, AF172625, AF172626 Genomic DNA. Translation: AAB33459.1.
AY228336 Genomic DNA. Translation: AAO38053.1.
AK314831 mRNA. Translation: BAG37351.1.
CH471198 Genomic DNA. Translation: EAW51891.1.
BC003135 mRNA. Translation: AAH03135.1.
BC050639 mRNA. Translation: AAH50639.1.
AF279657 Genomic DNA. Translation: AAK69488.1.
S80081 Genomic DNA. Translation: AAB47018.1.
CCDSiCCDS34766.1.
RefSeqiNP_000411.1. NM_000420.2.
UniGeneiHs.368588.

Genome annotation databases

EnsembliENST00000355265; ENSP00000347409; ENSG00000197993.
ENST00000561891; ENSP00000457677; ENSG00000260040.
GeneIDi3792.
KEGGihsa:3792.
UCSCiuc003wcb.3. human.

Polymorphism databases

DMDMi1346376.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Web resourcesi

dbRBC/BGMUT

Blood group antigen gene mutation database

SeattleSNPs

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64934 mRNA. Translation: AAA03192.1 .
AF172627
, AF172609 , AF172610 , AF172611 , AF172612 , AF172613 , AF172614 , AF172615 , AF172616 , AF172617 , AF172618 , AF172619 , AF172620 , AF172621 , AF172622 , AF172623 , AF172624 , AF172625 , AF172626 Genomic DNA. Translation: AAB33459.1 .
AY228336 Genomic DNA. Translation: AAO38053.1 .
AK314831 mRNA. Translation: BAG37351.1 .
CH471198 Genomic DNA. Translation: EAW51891.1 .
BC003135 mRNA. Translation: AAH03135.1 .
BC050639 mRNA. Translation: AAH50639.1 .
AF279657 Genomic DNA. Translation: AAK69488.1 .
S80081 Genomic DNA. Translation: AAB47018.1 .
CCDSi CCDS34766.1.
RefSeqi NP_000411.1. NM_000420.2.
UniGenei Hs.368588.

3D structure databases

ProteinModelPortali P23276.
SMRi P23276. Positions 313-732.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 109993. 4 interactions.
IntActi P23276. 2 interactions.
MINTi MINT-1464824.
STRINGi 9606.ENSP00000347409.

Protein family/group databases

MEROPSi M13.090.

PTM databases

PhosphoSitei P23276.

Polymorphism databases

DMDMi 1346376.

Proteomic databases

MaxQBi P23276.
PaxDbi P23276.
PRIDEi P23276.

Protocols and materials databases

DNASUi 3792.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000355265 ; ENSP00000347409 ; ENSG00000197993 .
ENST00000561891 ; ENSP00000457677 ; ENSG00000260040 .
GeneIDi 3792.
KEGGi hsa:3792.
UCSCi uc003wcb.3. human.

Organism-specific databases

CTDi 3792.
GeneCardsi GC07M142638.
HGNCi HGNC:6308. KEL.
HPAi HPA042391.
MIMi 110900. phenotype.
613883. gene.
neXtProti NX_P23276.
Orphaneti 157938. Joker disease.
PharmGKBi PA30087.
GenAtlasi Search...

Phylogenomic databases

eggNOGi COG3590.
HOGENOMi HOG000245574.
HOVERGENi HBG002194.
InParanoidi P23276.
KOi K06577.
OMAi SYAQVMC.
PhylomeDBi P23276.
TreeFami TF315192.

Miscellaneous databases

GenomeRNAii 3792.
NextBioi 14891.
PROi P23276.
SOURCEi Search...

Gene expression databases

ArrayExpressi P23276.
Bgeei P23276.
CleanExi HS_KEL.
Genevestigatori P23276.

Family and domain databases

InterProi IPR000718. Peptidase_M13.
IPR018497. Peptidase_M13_C.
IPR008753. Peptidase_M13_N.
[Graphical view ]
PANTHERi PTHR11733. PTHR11733. 1 hit.
Pfami PF01431. Peptidase_M13. 1 hit.
PF05649. Peptidase_M13_N. 1 hit.
[Graphical view ]
PRINTSi PR00786. NEPRILYSIN.
PROSITEi PS00142. ZINC_PROTEASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and primary structure of Kell blood group protein."
    Lee S., Zambas E.D., Marsh W.L., Redman C.M.
    Proc. Natl. Acad. Sci. U.S.A. 88:6353-6357(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
  2. "Organization of the gene encoding the human Kell blood group protein."
    Lee S., Zambas E., Green E.D., Redman C.M.
    Blood 85:1364-1370(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  3. SeattleSNPs variation discovery resource
    Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], VARIANTS THR-163; MET-193; TRP-281; PRO-597 AND ALA-726.
  4. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Brain and Skin.
  7. "PCR amplification and sequencing of the human KEL gene."
    Denomme G.A., Matheson K.A.
    Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 225-308.
  8. "Molecular basis of the K:6,-7 [Js(a+b-)] phenotype in the Kell blood group system."
    Lee S., Wu X., Reid M.E., Redman C.M.
    Transfusion 35:822-825(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 569-647, VARIANT BLOOD GROUP KEL6/KEL7.
  9. "Association of XK and Kell blood group proteins."
    Russo D., Redman C., Lee S.
    J. Biol. Chem. 273:13950-13956(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH XK, DISULFIDE BOND, MUTAGENESIS OF CYS-72 AND CYS-319.
  10. "Proteolytic processing of big endothelin-3 by the kell blood group protein."
    Lee S., Lin M., Mele A., Cao Y., Farmar J., Russo D., Redman C.
    Blood 94:1440-1450(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, MUTAGENESIS OF GLU-582.
  11. "Expression of Kell blood group protein in nonerythroid tissues."
    Russo D., Wu X., Redman C.M., Lee S.
    Blood 96:340-346(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, INTERACTION WITH XK.
  12. "Transcriptional regulation of the KEL gene and Kell protein expression in erythroid and non-erythroid cells."
    Camara-Clayette V., Rahuel C., Lopez C., Hattab C., Verkarre V., Bertrand O., Cartron J.P.
    Biochem. J. 356:171-180(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY, GLYCOSYLATION.
  13. "Molecular basis of the Kell (K1) phenotype."
    Lee S., Wu X., Reid M.E., Zelinski T., Redman C.M.
    Blood 85:912-916(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANT BLOOD GROUP KEL1/KEL2 MET-193.
  14. "Point mutations characterize KEL10, the KEL3, KEL4, and KEL21 alleles, and the KEL17 and KEL11 alleles."
    Lee S., Wu X., Son S., Naime D., Reid M.E., Okubo Y., Sistonen P., Redman C.M.
    Transfusion 36:490-494(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: VARIANTS BLOOD GROUP KEL3/KEL4/KEL21; KEL11/17 AND KEL10.

Entry informationi

Entry nameiKELL_HUMAN
AccessioniPrimary (citable) accession number: P23276
Secondary accession number(s): B2RBV4, Q96RS8, Q99885
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: February 1, 1996
Last modified: July 9, 2014
This is version 148 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Blood group antigen proteins
    Nomenclature of blood group antigens and list of entries
  2. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  3. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  5. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  6. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  7. Peptidase families
    Classification of peptidase families and list of entries
  8. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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