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P23269

- O1496_RAT

UniProt

P23269 - O1496_RAT

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Protein

Olfactory receptor 1496

Gene

Olr1496

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1496
Alternative name(s):
Olfactory receptor-like protein I3
Gene namesi
Name:Olr1496
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi1332757. Olr1496.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2323ExtracellularSequence AnalysisAdd
BLAST
Transmembranei24 – 4825Helical; Name=1Sequence AnalysisAdd
BLAST
Topological domaini49 – 557CytoplasmicSequence Analysis
Transmembranei56 – 7722Helical; Name=2Sequence AnalysisAdd
BLAST
Topological domaini78 – 9821ExtracellularSequence AnalysisAdd
BLAST
Transmembranei99 – 11820Helical; Name=3Sequence AnalysisAdd
BLAST
Topological domaini119 – 13719CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei138 – 15619Helical; Name=4Sequence AnalysisAdd
BLAST
Topological domaini157 – 19438ExtracellularSequence AnalysisAdd
BLAST
Transmembranei195 – 21723Helical; Name=5Sequence AnalysisAdd
BLAST
Topological domaini218 – 23417CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei235 – 25824Helical; Name=6Sequence AnalysisAdd
BLAST
Topological domaini259 – 27012ExtracellularSequence AnalysisAdd
BLAST
Transmembranei271 – 29020Helical; Name=7Sequence AnalysisAdd
BLAST
Topological domaini291 – 31020CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 310310Olfactory receptor 1496PRO_0000150875Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi3 – 31N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi95 ↔ 187PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Expressioni

Tissue specificityi

Olfactory epithelium.

Gene expression databases

GenevestigatoriP23269.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000043978.

Structurei

3D structure databases

ProteinModelPortaliP23269.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGimaNOG12327.
HOGENOMiHOG000041362.
HOVERGENiHBG017625.
InParanoidiP23269.
PhylomeDBiP23269.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23269-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNQTFITQF LLLGLPIPEE HQHLFYALFL VMYLTTILGN LLIIVLVQLD
60 70 80 90 100
SQLHTPMYLF LSNLSFSDLC FSSVTMPKLL QNMRSQDTSI PYGGCLAQTY
110 120 130 140 150
FFMVFGDMES FLLVAMAYDR YVAICFPLHY TSIMSPKLCT CLVLLLWMLT
160 170 180 190 200
TSHAMMHTLL AARLSFCENN VVLNFFCDLF VLLKLACSDT YINELMIFIM
210 220 230 240 250
STLLIIIPFF LIVMSYARII SSILKVPSTQ GICKVFSTCG SHLSVVSLFY
260 270 280 290 300
GTIIGLYLCP AGNNSTVKEM VMAMMYTVVT PMLNPFIYSL RNRDMKRALI
310
RVICSMKITL
Length:310
Mass (Da):35,247
Last modified:November 1, 1991 - v1
Checksum:i9688233890205B19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64385 mRNA. Translation: AAA41748.1.
PIRiE23701.
UniGeneiRn.113469.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64385 mRNA. Translation: AAA41748.1 .
PIRi E23701.
UniGenei Rn.113469.

3D structure databases

ProteinModelPortali P23269.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000043978.

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 1332757. Olr1496.

Phylogenomic databases

eggNOGi maNOG12327.
HOGENOMi HOG000041362.
HOVERGENi HBG017625.
InParanoidi P23269.
PhylomeDBi P23269.

Gene expression databases

Genevestigatori P23269.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
    Buck L., Axel R.
    Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiO1496_RAT
AccessioniPrimary (citable) accession number: P23269
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 29, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3