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P23268

- O1082_RAT

UniProt

P23268 - O1082_RAT

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Protein

Olfactory receptor 1082

Gene

Olr1082

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. odorant binding Source: RGD
  3. olfactory receptor activity Source: InterPro

GO - Biological processi

  1. sensory perception of smell Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1082
Alternative name(s):
Olfactory receptor-like protein F12
Gene namesi
Name:Olr1082
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi727865. Olr1082.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: RGD
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 317317Olfactory receptor 1082PRO_0000150873Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi98 ↔ 190PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP23268.

Expressioni

Tissue specificityi

Olfactory epithelium.

Gene expression databases

GenevestigatoriP23268.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000049068.

Structurei

3D structure databases

ProteinModelPortaliP23268.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2626ExtracellularSequence AnalysisAdd
BLAST
Topological domaini52 – 587CytoplasmicSequence Analysis
Topological domaini81 – 10121ExtracellularSequence AnalysisAdd
BLAST
Topological domaini122 – 14019CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini160 – 19738ExtracellularSequence AnalysisAdd
BLAST
Topological domaini221 – 23717CytoplasmicSequence AnalysisAdd
BLAST
Topological domaini262 – 27312ExtracellularSequence AnalysisAdd
BLAST
Topological domaini294 – 31724CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei27 – 5125Helical; Name=1Sequence AnalysisAdd
BLAST
Transmembranei59 – 8022Helical; Name=2Sequence AnalysisAdd
BLAST
Transmembranei102 – 12120Helical; Name=3Sequence AnalysisAdd
BLAST
Transmembranei141 – 15919Helical; Name=4Sequence AnalysisAdd
BLAST
Transmembranei198 – 22023Helical; Name=5Sequence AnalysisAdd
BLAST
Transmembranei238 – 26124Helical; Name=6Sequence AnalysisAdd
BLAST
Transmembranei274 – 29320Helical; Name=7Sequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3656.
HOGENOMiHOG000041364.
HOVERGENiHBG017625.
InParanoidiP23268.
KOiK04257.
PhylomeDBiP23268.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23268-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MESGNSTRRF SSFFLLGFTE NPQLHFLIFA LFLSMYLVTV LGNLLIIMAI
60 70 80 90 100
ITQSHLHTPM YFFLANLSFV DICFTSTTIP KMLVNIYTQS KSITYEDCIS
110 120 130 140 150
QMCVFLVFAE LGNFLLAVMA YDRYVAXCHP LCYTVIVNHR LCILLLLLSW
160 170 180 190 200
VISIFHAFIQ SLIVLQLTFC GDVKIPHFFC ELNQLSQLTC SDNFPSHLIM
210 220 230 240 250
NLVPVMLAAI SFSGILYSYF KIVSSIHSIS TVQGKYKAFS TCASHLSIVS
260 270 280 290 300
LFYSTGLGVY VSSAVVQSSH SAASASVMYT VVTPMLNPFI YSLRNKDVKR
310
ALERLLEGNC KVHHWTG
Length:317
Mass (Da):35,656
Last modified:November 1, 1991 - v1
Checksum:i3C3A15E9B776DAE6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64381 mRNA. Translation: AAA41744.1.
PIRiD23701.
RefSeqiNP_775457.1. NM_173335.1.
UniGeneiRn.44383.

Genome annotation databases

GeneIDi287002.
KEGGirno:287002.
UCSCiRGD:727865. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M64381 mRNA. Translation: AAA41744.1 .
PIRi D23701.
RefSeqi NP_775457.1. NM_173335.1.
UniGenei Rn.44383.

3D structure databases

ProteinModelPortali P23268.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10116.ENSRNOP00000049068.

Protein family/group databases

GPCRDBi Search...

Proteomic databases

PRIDEi P23268.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 287002.
KEGGi rno:287002.
UCSCi RGD:727865. rat.

Organism-specific databases

CTDi 287002.
RGDi 727865. Olr1082.

Phylogenomic databases

eggNOGi KOG3656.
HOGENOMi HOG000041364.
HOVERGENi HBG017625.
InParanoidi P23268.
KOi K04257.
PhylomeDBi P23268.

Miscellaneous databases

NextBioi 625305.

Gene expression databases

Genevestigatori P23268.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
    Buck L., Axel R.
    Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiO1082_RAT
AccessioniPrimary (citable) accession number: P23268
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 29, 2014
This is version 100 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3