P23268 (O1082_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Olfactory receptor 1082

Alternative name(s):
Olfactory receptor-like protein F12

Gene names

Name:

Olr1082

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	317 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Odorant receptor Potential.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Tissue specificity	Olfactory epithelium.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family.

Ontologies

Keywords
Biological process	Olfaction Sensory transduction
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	detection of chemical stimulus involved in sensory perception of smell Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from sequence or structural similarity Ref.1. Source: RGD plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW odorant binding Inferred from sequence or structural similarity Ref.1. Source: RGD olfactory receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 317	317	Olfactory receptor 1082		PRO_0000150873
Regions
	Topological domain	1 – 26	26	Extracellular Potential
	Transmembrane	27 – 51	25	Helical; Name=1; Potential
	Topological domain	52 – 58	7	Cytoplasmic Potential
	Transmembrane	59 – 80	22	Helical; Name=2; Potential
	Topological domain	81 – 101	21	Extracellular Potential
	Transmembrane	102 – 121	20	Helical; Name=3; Potential
	Topological domain	122 – 140	19	Cytoplasmic Potential
	Transmembrane	141 – 159	19	Helical; Name=4; Potential
	Topological domain	160 – 197	38	Extracellular Potential
	Transmembrane	198 – 220	23	Helical; Name=5; Potential
	Topological domain	221 – 237	17	Cytoplasmic Potential
	Transmembrane	238 – 261	24	Helical; Name=6; Potential
	Topological domain	262 – 273	12	Extracellular Potential
	Transmembrane	274 – 293	20	Helical; Name=7; Potential
	Topological domain	294 – 317	24	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	5	1	N-linked (GlcNAc...) Potential
	Disulfide bond	98 ↔ 190		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P23268 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 3C3A15E9B776DAE6	FASTA	317	35,656
	10 20 30 40 50 60 MESGNSTRRF SSFFLLGFTE NPQLHFLIFA LFLSMYLVTV LGNLLIIMAI ITQSHLHTPM 70 80 90 100 110 120 YFFLANLSFV DICFTSTTIP KMLVNIYTQS KSITYEDCIS QMCVFLVFAE LGNFLLAVMA 130 140 150 160 170 180 YDRYVAXCHP LCYTVIVNHR LCILLLLLSW VISIFHAFIQ SLIVLQLTFC GDVKIPHFFC 190 200 210 220 230 240 ELNQLSQLTC SDNFPSHLIM NLVPVMLAAI SFSGILYSYF KIVSSIHSIS TVQGKYKAFS 250 260 270 280 290 300 TCASHLSIVS LFYSTGLGVY VSSAVVQSSH SAASASVMYT VVTPMLNPFI YSLRNKDVKR 310 ALERLLEGNC KVHHWTG

References

[1]	"A novel multigene family may encode odorant receptors: a molecular basis for odor recognition." Buck L., Axel R. Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M64381 mRNA. Translation: AAA41744.1.
IPI	IPI00209154.
PIR	D23701.
RefSeq	NP_775457.1. NM_173335.1.
UniGene	Rn.44383.
3D structure databases
ProteinModelPortal	P23268.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000049068.
Protein family/group databases
GPCRDB	Search...
Proteomic databases
PRIDE	P23268.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	287002.
KEGG	rno:287002.
UCSC	RGD:727865. rat.
Organism-specific databases
CTD	287002.
RGD	727865. Olr1082.
Phylogenomic databases
eggNOG	KOG3656.
HOGENOM	HOG000041364.
HOVERGEN	HBG017625.
InParanoid	P23268.
KO	K04257.
OrthoDB	EOG4WQ14G.
Gene expression databases
Genevestigator	P23268.
GermOnline	ENSRNOG00000031936. Rattus norvegicus.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	625305.

Entry information

Entry name

O1082_RAT

Accession

Primary (citable) accession number: P23268

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	April 3, 2013
This is version 92 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program