ID   OL287_RAT               Reviewed;         311 AA.
AC   P23267;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   24-JAN-2024, entry version 132.
DE   RecName: Full=Olfactory receptor 287;
DE   AltName: Full=Olfactory receptor-like protein F6;
GN   Name=Olr287;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1840504; DOI=10.1016/0092-8674(91)90418-x;
RA   Buck L., Axel R.;
RT   "A novel multigene family may encode odorant receptors: a molecular basis
RT   for odor recognition.";
RL   Cell 65:175-187(1991).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Olfactory epithelium.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; M64378; AAA41741.1; -; mRNA.
DR   PIR; C23701; C23701.
DR   RefSeq; NP_775456.1; NM_173334.1.
DR   RefSeq; XP_017444336.1; XM_017588847.1.
DR   RefSeq; XP_017444337.1; XM_017588848.1.
DR   AlphaFoldDB; P23267; -.
DR   SMR; P23267; -.
DR   STRING; 10116.ENSRNOP00000064135; -.
DR   GlyCosmos; P23267; 1 site, No reported glycans.
DR   GlyGen; P23267; 1 site.
DR   PaxDb; 10116-ENSRNOP00000064135; -.
DR   Ensembl; ENSRNOT00000108613.1; ENSRNOP00000090395.1; ENSRNOG00000067810.1.
DR   Ensembl; ENSRNOT00055048506; ENSRNOP00055039871; ENSRNOG00055028035.
DR   Ensembl; ENSRNOT00060046122; ENSRNOP00060038311; ENSRNOG00060026631.
DR   Ensembl; ENSRNOT00065030031; ENSRNOP00065023874; ENSRNOG00065017933.
DR   GeneID; 287001; -.
DR   KEGG; rno:287001; -.
DR   UCSC; RGD:727837; rat.
DR   AGR; RGD:727837; -.
DR   CTD; 258511; -.
DR   RGD; 727837; Olr287.
DR   eggNOG; ENOG502SIF0; Eukaryota.
DR   GeneTree; ENSGT01090000260086; -.
DR   HOGENOM; CLU_012526_1_0_1; -.
DR   InParanoid; P23267; -.
DR   OMA; WIVLSCS; -.
DR   OrthoDB; 4834013at2759; -.
DR   PhylomeDB; P23267; -.
DR   PRO; PR:P23267; -.
DR   Proteomes; UP000002494; Chromosome 1.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   CDD; cd13954; 7tmA_OR; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   InterPro; IPR047132; Olfact_rcpt_6C-like.
DR   PANTHER; PTHR26454; OLFACTORY RECEPTOR; 1.
DR   PANTHER; PTHR26454:SF73; OLFACTORY RECEPTOR; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   Genevisible; P23267; RN.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..311
FT                   /note="Olfactory receptor 287"
FT                   /id="PRO_0000150871"
FT   TOPO_DOM        1..27
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        28..53
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        54..60
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        61..82
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        83..103
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..123
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        124..142
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        143..161
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        162..199
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..222
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        223..239
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        240..263
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        264..275
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        276..295
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        296..311
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        8
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        100..192
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   311 AA;  34169 MW;  9E092CFE85A58BF1 CRC64;
     MAWSTGQNLS TPGPFILLGF PGPRSMRIGL FLLFLVMYLL TVVGNLAIIS LVGAHRCLQT
     PMYFFLCNLS FLEIWFTTAC VPKTLATFAP RGGVISLAGC ATQMYFVFSL GCTEYFLLAV
     MAYDRYLAIC LPLRYGGIMT PGLAMRLALG SWLCGFSAIT VPATLIARLS FCGSRVINHF
     FCDISPWIVL SCTDTQVVEL VSFGIAFCVI LGSCGITLVS YAYIITTIIK IPSARGRHRA
     FSTCSSHLTV VLIWYGSTIF LHVRTSVESS LDLTKAITVL NTIVTPVLNP FIYTLRNKDV
     KEALRRTVKG K
//