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P23267 (OL287_RAT) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 90. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Olfactory receptor 287
Alternative name(s):
Olfactory receptor-like protein F6
Gene names
Name:Olr287
OrganismRattus norvegicus (Rat) [Reference proteome]
Taxonomic identifier10116 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Odorant receptor Potential.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Tissue specificity

Olfactory epithelium.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Olfactory receptor 287
PRO_0000150871

Regions

Topological domain1 – 2727Extracellular Potential
Transmembrane28 – 5326Helical; Name=1; Potential
Topological domain54 – 607Cytoplasmic Potential
Transmembrane61 – 8222Helical; Name=2; Potential
Topological domain83 – 10321Extracellular Potential
Transmembrane104 – 12320Helical; Name=3; Potential
Topological domain124 – 14219Cytoplasmic Potential
Transmembrane143 – 16119Helical; Name=4; Potential
Topological domain162 – 19938Extracellular Potential
Transmembrane200 – 22223Helical; Name=5; Potential
Topological domain223 – 23917Cytoplasmic Potential
Transmembrane240 – 26324Helical; Name=6; Potential
Topological domain264 – 27512Extracellular Potential
Transmembrane276 – 29520Helical; Name=7; Potential
Topological domain296 – 31116Cytoplasmic Potential

Amino acid modifications

Glycosylation81N-linked (GlcNAc...) Potential
Disulfide bond100 ↔ 192 By similarity

Sequences

Sequence LengthMass (Da)Tools
P23267 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 9E092CFE85A58BF1

FASTA31134,169
        10         20         30         40         50         60 
MAWSTGQNLS TPGPFILLGF PGPRSMRIGL FLLFLVMYLL TVVGNLAIIS LVGAHRCLQT 

        70         80         90        100        110        120 
PMYFFLCNLS FLEIWFTTAC VPKTLATFAP RGGVISLAGC ATQMYFVFSL GCTEYFLLAV 

       130        140        150        160        170        180 
MAYDRYLAIC LPLRYGGIMT PGLAMRLALG SWLCGFSAIT VPATLIARLS FCGSRVINHF 

       190        200        210        220        230        240 
FCDISPWIVL SCTDTQVVEL VSFGIAFCVI LGSCGITLVS YAYIITTIIK IPSARGRHRA 

       250        260        270        280        290        300 
FSTCSSHLTV VLIWYGSTIF LHVRTSVESS LDLTKAITVL NTIVTPVLNP FIYTLRNKDV 

       310 
KEALRRTVKG K 

« Hide

References

[1]"A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
Buck L., Axel R.
Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M64378 mRNA. Translation: AAA41741.1.
PIRC23701.
RefSeqNP_775456.1. NM_173334.1.
XP_006230585.1. XM_006230523.1.
UniGeneRn.44382.

3D structure databases

ProteinModelPortalP23267.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

GPCRDBSearch...

Proteomic databases

PRIDEP23267.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSRNOT00000025635; ENSRNOP00000064135; ENSRNOG00000018956.
GeneID287001.
KEGGrno:287001.
UCSCRGD:727837. rat.

Organism-specific databases

CTD287001.
RGD727837. Olr287.

Phylogenomic databases

GeneTreeENSGT00730000110765.
HOVERGENHBG017625.
KOK04257.
OMAGIMTPGL.
OrthoDBEOG71K63J.
PhylomeDBP23267.

Gene expression databases

GenevestigatorP23267.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PfamPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio625301.

Entry information

Entry nameOL287_RAT
AccessionPrimary (citable) accession number: P23267
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: April 16, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries