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Protein

Olfactory receptor 287

Gene

Olr287

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

  • G-protein coupled receptor activity Source: UniProtKB-KW
  • odorant binding Source: RGD
  • olfactory receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 287
Alternative name(s):
Olfactory receptor-like protein F6
Gene namesi
Name:Olr287
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 1

Organism-specific databases

RGDi727837. Olr287.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 27ExtracellularSequence analysisAdd BLAST27
Transmembranei28 – 53Helical; Name=1Sequence analysisAdd BLAST26
Topological domaini54 – 60CytoplasmicSequence analysis7
Transmembranei61 – 82Helical; Name=2Sequence analysisAdd BLAST22
Topological domaini83 – 103ExtracellularSequence analysisAdd BLAST21
Transmembranei104 – 123Helical; Name=3Sequence analysisAdd BLAST20
Topological domaini124 – 142CytoplasmicSequence analysisAdd BLAST19
Transmembranei143 – 161Helical; Name=4Sequence analysisAdd BLAST19
Topological domaini162 – 199ExtracellularSequence analysisAdd BLAST38
Transmembranei200 – 222Helical; Name=5Sequence analysisAdd BLAST23
Topological domaini223 – 239CytoplasmicSequence analysisAdd BLAST17
Transmembranei240 – 263Helical; Name=6Sequence analysisAdd BLAST24
Topological domaini264 – 275ExtracellularSequence analysisAdd BLAST12
Transmembranei276 – 295Helical; Name=7Sequence analysisAdd BLAST20
Topological domaini296 – 311CytoplasmicSequence analysisAdd BLAST16

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001508711 – 311Olfactory receptor 287Add BLAST311

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi8N-linked (GlcNAc...)Sequence analysis1
Disulfide bondi100 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiP23267.
PRIDEiP23267.

Expressioni

Tissue specificityi

Olfactory epithelium.

Gene expression databases

GenevisibleiP23267. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064135.

Structurei

3D structure databases

ProteinModelPortaliP23267.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410ISHC. Eukaryota.
ENOG410Z9YX. LUCA.
GeneTreeiENSGT00760000119169.
HOVERGENiHBG017625.
InParanoidiP23267.
KOiK04257.
OMAiPRSMRIG.
OrthoDBiEOG091G0AZH.
PhylomeDBiP23267.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23267-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAWSTGQNLS TPGPFILLGF PGPRSMRIGL FLLFLVMYLL TVVGNLAIIS
60 70 80 90 100
LVGAHRCLQT PMYFFLCNLS FLEIWFTTAC VPKTLATFAP RGGVISLAGC
110 120 130 140 150
ATQMYFVFSL GCTEYFLLAV MAYDRYLAIC LPLRYGGIMT PGLAMRLALG
160 170 180 190 200
SWLCGFSAIT VPATLIARLS FCGSRVINHF FCDISPWIVL SCTDTQVVEL
210 220 230 240 250
VSFGIAFCVI LGSCGITLVS YAYIITTIIK IPSARGRHRA FSTCSSHLTV
260 270 280 290 300
VLIWYGSTIF LHVRTSVESS LDLTKAITVL NTIVTPVLNP FIYTLRNKDV
310
KEALRRTVKG K
Length:311
Mass (Da):34,169
Last modified:November 1, 1991 - v1
Checksum:i9E092CFE85A58BF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64378 mRNA. Translation: AAA41741.1.
PIRiC23701.
RefSeqiNP_775456.1. NM_173334.1.
XP_017444336.1. XM_017588847.1.
XP_017444337.1. XM_017588848.1.
UniGeneiRn.44382.

Genome annotation databases

EnsembliENSRNOT00000025635; ENSRNOP00000064135; ENSRNOG00000018956.
GeneIDi287001.
KEGGirno:287001.
UCSCiRGD:727837. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64378 mRNA. Translation: AAA41741.1.
PIRiC23701.
RefSeqiNP_775456.1. NM_173334.1.
XP_017444336.1. XM_017588847.1.
XP_017444337.1. XM_017588848.1.
UniGeneiRn.44382.

3D structure databases

ProteinModelPortaliP23267.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000064135.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiP23267.
PRIDEiP23267.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000025635; ENSRNOP00000064135; ENSRNOG00000018956.
GeneIDi287001.
KEGGirno:287001.
UCSCiRGD:727837. rat.

Organism-specific databases

CTDi287001.
RGDi727837. Olr287.

Phylogenomic databases

eggNOGiENOG410ISHC. Eukaryota.
ENOG410Z9YX. LUCA.
GeneTreeiENSGT00760000119169.
HOVERGENiHBG017625.
InParanoidiP23267.
KOiK04257.
OMAiPRSMRIG.
OrthoDBiEOG091G0AZH.
PhylomeDBiP23267.

Miscellaneous databases

PROiP23267.

Gene expression databases

GenevisibleiP23267. RN.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiOL287_RAT
AccessioniPrimary (citable) accession number: P23267
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: November 30, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.