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P23267

- OL287_RAT

UniProt

P23267 - OL287_RAT

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Protein

Olfactory receptor 287

Gene

Olr287

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. odorant binding Source: RGD
  3. olfactory receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Enzyme and pathway databases

ReactomeiREACT_247084. Olfactory Signaling Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 287
Alternative name(s):
Olfactory receptor-like protein F6
Gene namesi
Name:Olr287
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Chromosome 1

Organism-specific databases

RGDi727837. Olr287.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2727ExtracellularSequence AnalysisAdd
BLAST
Transmembranei28 – 5326Helical; Name=1Sequence AnalysisAdd
BLAST
Topological domaini54 – 607CytoplasmicSequence Analysis
Transmembranei61 – 8222Helical; Name=2Sequence AnalysisAdd
BLAST
Topological domaini83 – 10321ExtracellularSequence AnalysisAdd
BLAST
Transmembranei104 – 12320Helical; Name=3Sequence AnalysisAdd
BLAST
Topological domaini124 – 14219CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei143 – 16119Helical; Name=4Sequence AnalysisAdd
BLAST
Topological domaini162 – 19938ExtracellularSequence AnalysisAdd
BLAST
Transmembranei200 – 22223Helical; Name=5Sequence AnalysisAdd
BLAST
Topological domaini223 – 23917CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei240 – 26324Helical; Name=6Sequence AnalysisAdd
BLAST
Topological domaini264 – 27512ExtracellularSequence AnalysisAdd
BLAST
Transmembranei276 – 29520Helical; Name=7Sequence AnalysisAdd
BLAST
Topological domaini296 – 31116CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Olfactory receptor 287PRO_0000150871Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi8 – 81N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi100 ↔ 192PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PRIDEiP23267.

Expressioni

Tissue specificityi

Olfactory epithelium.

Gene expression databases

GenevestigatoriP23267.

Structurei

3D structure databases

ProteinModelPortaliP23267.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00760000119169.
HOVERGENiHBG017625.
InParanoidiP23267.
KOiK04257.
OMAiGIMTPGL.
OrthoDBiEOG71K63J.
PhylomeDBiP23267.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23267-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAWSTGQNLS TPGPFILLGF PGPRSMRIGL FLLFLVMYLL TVVGNLAIIS
60 70 80 90 100
LVGAHRCLQT PMYFFLCNLS FLEIWFTTAC VPKTLATFAP RGGVISLAGC
110 120 130 140 150
ATQMYFVFSL GCTEYFLLAV MAYDRYLAIC LPLRYGGIMT PGLAMRLALG
160 170 180 190 200
SWLCGFSAIT VPATLIARLS FCGSRVINHF FCDISPWIVL SCTDTQVVEL
210 220 230 240 250
VSFGIAFCVI LGSCGITLVS YAYIITTIIK IPSARGRHRA FSTCSSHLTV
260 270 280 290 300
VLIWYGSTIF LHVRTSVESS LDLTKAITVL NTIVTPVLNP FIYTLRNKDV
310
KEALRRTVKG K
Length:311
Mass (Da):34,169
Last modified:November 1, 1991 - v1
Checksum:i9E092CFE85A58BF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64378 mRNA. Translation: AAA41741.1.
PIRiC23701.
RefSeqiNP_775456.1. NM_173334.1.
UniGeneiRn.44382.

Genome annotation databases

EnsembliENSRNOT00000025635; ENSRNOP00000064135; ENSRNOG00000018956.
GeneIDi287001.
KEGGirno:287001.
UCSCiRGD:727837. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64378 mRNA. Translation: AAA41741.1 .
PIRi C23701.
RefSeqi NP_775456.1. NM_173334.1.
UniGenei Rn.44382.

3D structure databases

ProteinModelPortali P23267.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Proteomic databases

PRIDEi P23267.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSRNOT00000025635 ; ENSRNOP00000064135 ; ENSRNOG00000018956 .
GeneIDi 287001.
KEGGi rno:287001.
UCSCi RGD:727837. rat.

Organism-specific databases

CTDi 287001.
RGDi 727837. Olr287.

Phylogenomic databases

GeneTreei ENSGT00760000119169.
HOVERGENi HBG017625.
InParanoidi P23267.
KOi K04257.
OMAi GIMTPGL.
OrthoDBi EOG71K63J.
PhylomeDBi P23267.

Enzyme and pathway databases

Reactomei REACT_247084. Olfactory Signaling Pathway.

Miscellaneous databases

NextBioi 625301.

Gene expression databases

Genevestigatori P23267.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
    Buck L., Axel R.
    Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiOL287_RAT
AccessioniPrimary (citable) accession number: P23267
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: November 26, 2014
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3