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P23267

- OL287_RAT

UniProt

P23267 - OL287_RAT

Protein

Olfactory receptor 287

Gene

Olr287

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 1 (01 Nov 1991)
      Previous versions | rss
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    Functioni

    Odorant receptor.Curated

    GO - Molecular functioni

    1. G-protein coupled receptor activity Source: UniProtKB-KW
    2. odorant binding Source: RGD
    3. olfactory receptor activity Source: InterPro

    Keywords - Molecular functioni

    G-protein coupled receptor, Receptor, Transducer

    Keywords - Biological processi

    Olfaction, Sensory transduction

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Olfactory receptor 287
    Alternative name(s):
    Olfactory receptor-like protein F6
    Gene namesi
    Name:Olr287
    OrganismiRattus norvegicus (Rat)
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
    ProteomesiUP000002494: Chromosome 1

    Organism-specific databases

    RGDi727837. Olr287.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 311311Olfactory receptor 287PRO_0000150871Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi8 – 81N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi100 ↔ 192PROSITE-ProRule annotation

    Keywords - PTMi

    Disulfide bond, Glycoprotein

    Proteomic databases

    PRIDEiP23267.

    Expressioni

    Tissue specificityi

    Olfactory epithelium.

    Gene expression databases

    GenevestigatoriP23267.

    Structurei

    3D structure databases

    ProteinModelPortaliP23267.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 2727ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini54 – 607CytoplasmicSequence Analysis
    Topological domaini83 – 10321ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini124 – 14219CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini162 – 19938ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini223 – 23917CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini264 – 27512ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini296 – 31116CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei28 – 5326Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei61 – 8222Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei104 – 12320Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei143 – 16119Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei200 – 22223Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei240 – 26324Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei276 – 29520Helical; Name=7Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    GeneTreeiENSGT00730000110765.
    HOVERGENiHBG017625.
    KOiK04257.
    OMAiGIMTPGL.
    OrthoDBiEOG71K63J.
    PhylomeDBiP23267.

    Family and domain databases

    Gene3Di1.20.1070.10. 1 hit.
    InterProiIPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view]
    PfamiPF00001. 7tm_1. 1 hit.
    [Graphical view]
    PRINTSiPR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P23267-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAWSTGQNLS TPGPFILLGF PGPRSMRIGL FLLFLVMYLL TVVGNLAIIS    50
    LVGAHRCLQT PMYFFLCNLS FLEIWFTTAC VPKTLATFAP RGGVISLAGC 100
    ATQMYFVFSL GCTEYFLLAV MAYDRYLAIC LPLRYGGIMT PGLAMRLALG 150
    SWLCGFSAIT VPATLIARLS FCGSRVINHF FCDISPWIVL SCTDTQVVEL 200
    VSFGIAFCVI LGSCGITLVS YAYIITTIIK IPSARGRHRA FSTCSSHLTV 250
    VLIWYGSTIF LHVRTSVESS LDLTKAITVL NTIVTPVLNP FIYTLRNKDV 300
    KEALRRTVKG K 311
    Length:311
    Mass (Da):34,169
    Last modified:November 1, 1991 - v1
    Checksum:i9E092CFE85A58BF1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64378 mRNA. Translation: AAA41741.1.
    PIRiC23701.
    RefSeqiNP_775456.1. NM_173334.1.
    XP_006230585.1. XM_006230523.1.
    UniGeneiRn.44382.

    Genome annotation databases

    EnsembliENSRNOT00000025635; ENSRNOP00000064135; ENSRNOG00000018956.
    GeneIDi287001.
    KEGGirno:287001.
    UCSCiRGD:727837. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64378 mRNA. Translation: AAA41741.1 .
    PIRi C23701.
    RefSeqi NP_775456.1. NM_173334.1.
    XP_006230585.1. XM_006230523.1.
    UniGenei Rn.44382.

    3D structure databases

    ProteinModelPortali P23267.
    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    GPCRDBi Search...

    Proteomic databases

    PRIDEi P23267.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSRNOT00000025635 ; ENSRNOP00000064135 ; ENSRNOG00000018956 .
    GeneIDi 287001.
    KEGGi rno:287001.
    UCSCi RGD:727837. rat.

    Organism-specific databases

    CTDi 287001.
    RGDi 727837. Olr287.

    Phylogenomic databases

    GeneTreei ENSGT00730000110765.
    HOVERGENi HBG017625.
    KOi K04257.
    OMAi GIMTPGL.
    OrthoDBi EOG71K63J.
    PhylomeDBi P23267.

    Miscellaneous databases

    NextBioi 625301.

    Gene expression databases

    Genevestigatori P23267.

    Family and domain databases

    Gene3Di 1.20.1070.10. 1 hit.
    InterProi IPR000276. GPCR_Rhodpsn.
    IPR017452. GPCR_Rhodpsn_7TM.
    IPR000725. Olfact_rcpt.
    [Graphical view ]
    Pfami PF00001. 7tm_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00237. GPCRRHODOPSN.
    PR00245. OLFACTORYR.
    PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
    PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
      Buck L., Axel R.
      Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].

    Entry informationi

    Entry nameiOL287_RAT
    AccessioniPrimary (citable) accession number: P23267
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: November 1, 1991
    Last modified: October 1, 2014
    This is version 91 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. 7-transmembrane G-linked receptors
      List of 7-transmembrane G-linked receptor entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3