ID   O1361_RAT               Reviewed;         313 AA.
AC   P23266;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   27-MAR-2024, entry version 148.
DE   RecName: Full=Olfactory receptor 1f45;
DE   AltName: Full=Olfactory receptor 1361;
DE   AltName: Full=Olfactory receptor-like protein F5;
GN   Name=Or1f45;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=1840504; DOI=10.1016/0092-8674(91)90418-x;
RA   Buck L., Axel R.;
RT   "A novel multigene family may encode odorant receptors: a molecular basis
RT   for odor recognition.";
RL   Cell 65:175-187(1991).
CC   -!- FUNCTION: Odorant receptor. {ECO:0000305}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- TISSUE SPECIFICITY: Olfactory epithelium.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC       {ECO:0000255|PROSITE-ProRule:PRU00521}.
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DR   EMBL; M64377; AAA41740.1; -; mRNA.
DR   PIR; B23701; B23701.
DR   RefSeq; NP_775455.1; NM_173333.1.
DR   AlphaFoldDB; P23266; -.
DR   SMR; P23266; -.
DR   STRING; 10116.ENSRNOP00000064717; -.
DR   GlyCosmos; P23266; 1 site, No reported glycans.
DR   GlyGen; P23266; 1 site.
DR   PaxDb; 10116-ENSRNOP00000064717; -.
DR   Ensembl; ENSRNOT00000071686.2; ENSRNOP00000064717.1; ENSRNOG00000067846.1.
DR   GeneID; 287000; -.
DR   KEGG; rno:287000; -.
DR   UCSC; RGD:708422; rat.
DR   AGR; RGD:41356480; -.
DR   AGR; RGD:708422; -.
DR   CTD; 287000; -.
DR   RGD; 708422; Or1f45.
DR   eggNOG; ENOG502SHUD; Eukaryota.
DR   GeneTree; ENSGT00940000153683; -.
DR   HOGENOM; CLU_012526_1_3_1; -.
DR   InParanoid; P23266; -.
DR   OrthoDB; 5401587at2759; -.
DR   PhylomeDB; P23266; -.
DR   TreeFam; TF337210; -.
DR   PRO; PR:P23266; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR   GO; GO:0004984; F:olfactory receptor activity; IBA:GO_Central.
DR   GO; GO:0007165; P:signal transduction; IBA:GO_Central.
DR   CDD; cd15918; 7tmA_OR1_7-like; 1.
DR   Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   InterPro; IPR000725; Olfact_rcpt.
DR   PANTHER; PTHR48001; OLFACTORY RECEPTOR; 1.
DR   PANTHER; PTHR48001:SF10; OLFACTORY RECEPTOR 1J4; 1.
DR   Pfam; PF13853; 7tm_4; 1.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   PRINTS; PR00245; OLFACTORYR.
DR   SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR   PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
DR   Genevisible; P23266; RN.
PE   2: Evidence at transcript level;
KW   Cell membrane; Disulfide bond; G-protein coupled receptor; Glycoprotein;
KW   Membrane; Olfaction; Receptor; Reference proteome; Sensory transduction;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..313
FT                   /note="Olfactory receptor 1f45"
FT                   /id="PRO_0000150874"
FT   TOPO_DOM        1..25
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        26..50
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        51..57
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..79
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        80..100
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        101..120
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        121..139
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..158
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..196
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..219
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        220..236
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        237..260
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        261..272
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..292
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        293..313
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        5
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        97..189
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00521"
SQ   SEQUENCE   313 AA;  34703 MW;  2FD7BCD6E36D8815 CRC64;
     MSSTNQSSVT EFLLLGLSRQ PQQQQLLFLL FLIMYLATVL GNLLIILAIG TDSRLHTPMY
     FFLSNLSFVD VCFSSTTVPK VLANHILGSQ AISFSGCLTQ LYFLAVFGNM DNFLLAVMSY
     DRFVAICHPL HYTTKMTRQL CVLLVVGSWV VANMNCLLHI LLMARLSFCA DNMIPHFFCD
     GTPLLKLSCS DTHLNELMIL TEGAVVMVTP FVCILISYIH ITCAVLRVSS PRGGWKSFST
     CGSHLAVVCL FYGTVIAVYF NPSSSHLAGR DMAAAVMYAV VTPMLNPFIY SLRNSDMKAA
     LRKVLAMRFP SKQ
//