P23266 (O1361_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Olfactory receptor 1361

Alternative name(s):
Olfactory receptor-like protein F5

Gene names

Name:

Olr1361

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	313 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Odorant receptor Potential.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Tissue specificity	Olfactory epithelium.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family.

Ontologies

Keywords
Biological process	Olfaction Sensory transduction
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW olfactory receptor activity Inferred from sequence or structural similarity Ref.1. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 313	313	Olfactory receptor 1361		PRO_0000150874
Regions
	Topological domain	1 – 25	25	Extracellular Potential
	Transmembrane	26 – 50	25	Helical; Name=1; Potential
	Topological domain	51 – 57	7	Cytoplasmic Potential
	Transmembrane	58 – 79	22	Helical; Name=2; Potential
	Topological domain	80 – 100	21	Extracellular Potential
	Transmembrane	101 – 120	20	Helical; Name=3; Potential
	Topological domain	121 – 139	19	Cytoplasmic Potential
	Transmembrane	140 – 158	19	Helical; Name=4; Potential
	Topological domain	159 – 196	38	Extracellular Potential
	Transmembrane	197 – 219	23	Helical; Name=5; Potential
	Topological domain	220 – 236	17	Cytoplasmic Potential
	Transmembrane	237 – 260	24	Helical; Name=6; Potential
	Topological domain	261 – 272	12	Extracellular Potential
	Transmembrane	273 – 292	20	Helical; Name=7; Potential
	Topological domain	293 – 313	21	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	5	1	N-linked (GlcNAc...) Potential
	Disulfide bond	97 ↔ 189		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P23266 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 2FD7BCD6E36D8815	FASTA	313	34,703
	10 20 30 40 50 60 MSSTNQSSVT EFLLLGLSRQ PQQQQLLFLL FLIMYLATVL GNLLIILAIG TDSRLHTPMY 70 80 90 100 110 120 FFLSNLSFVD VCFSSTTVPK VLANHILGSQ AISFSGCLTQ LYFLAVFGNM DNFLLAVMSY 130 140 150 160 170 180 DRFVAICHPL HYTTKMTRQL CVLLVVGSWV VANMNCLLHI LLMARLSFCA DNMIPHFFCD 190 200 210 220 230 240 GTPLLKLSCS DTHLNELMIL TEGAVVMVTP FVCILISYIH ITCAVLRVSS PRGGWKSFST 250 260 270 280 290 300 CGSHLAVVCL FYGTVIAVYF NPSSSHLAGR DMAAAVMYAV VTPMLNPFIY SLRNSDMKAA 310 LRKVLAMRFP SKQ

References

[1]	"A novel multigene family may encode odorant receptors: a molecular basis for odor recognition." Buck L., Axel R. Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M64377 mRNA. Translation: AAA41740.1.
IPI	IPI00209149.
PIR	B23701.
RefSeq	NP_775455.1. NM_173333.1.
UniGene	Rn.44381.
3D structure databases
ProteinModelPortal	P23266.
ModBase	Search...
Protein-protein interaction databases
STRING	10116.ENSRNOP00000004503.
Protein family/group databases
GPCRDB	Search...
Proteomic databases
PRIDE	P23266.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSRNOT00000071686; ENSRNOP00000064717; ENSRNOG00000049716. ENSRNOT00000073280; ENSRNOP00000067373; ENSRNOG00000046341.
GeneID	287000.
KEGG	rno:287000.
UCSC	RGD:708422. rat.
Organism-specific databases
CTD	287000.
RGD	708422. Olr1361.
Phylogenomic databases
eggNOG	NOG150110.
GeneTree	ENSGT00700000104209.
HOGENOM	HOG000041365.
HOVERGEN	HBG017625.
InParanoid	P23266.
KO	K04257.
OMA	CADNRIS.
OrthoDB	EOG4MKNGZ.
Gene expression databases
ArrayExpress	P23266.
Genevestigator	P23266.
GermOnline	ENSRNOG00000003382. Rattus norvegicus.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
PANTHER	PTHR24236. PTHR24236. 1 hit.
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	625297.

Entry information

Entry name

O1361_RAT

Accession

Primary (citable) accession number: P23266

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	May 1, 2013
This is version 96 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program