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P23265

- O1078_RAT

UniProt

P23265 - O1078_RAT

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Protein

Olfactory receptor 1078

Gene

Olr1078

Organism
Rattus norvegicus (Rat)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Odorant receptor.Curated

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. olfactory receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Keywords - Biological processi

Olfaction, Sensory transduction

Names & Taxonomyi

Protein namesi
Recommended name:
Olfactory receptor 1078
Alternative name(s):
Olfactory receptor-like protein F3
Gene namesi
Name:Olr1078
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494: Unplaced

Organism-specific databases

RGDi1333657. Olr1078.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 2525ExtracellularSequence AnalysisAdd
BLAST
Transmembranei26 – 5025Helical; Name=1Sequence AnalysisAdd
BLAST
Topological domaini51 – 577CytoplasmicSequence Analysis
Transmembranei58 – 7922Helical; Name=2Sequence AnalysisAdd
BLAST
Topological domaini80 – 10021ExtracellularSequence AnalysisAdd
BLAST
Transmembranei101 – 12020Helical; Name=3Sequence AnalysisAdd
BLAST
Topological domaini121 – 13919CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei140 – 15819Helical; Name=4Sequence AnalysisAdd
BLAST
Topological domaini159 – 19638ExtracellularSequence AnalysisAdd
BLAST
Transmembranei197 – 21923Helical; Name=5Sequence AnalysisAdd
BLAST
Topological domaini220 – 23617CytoplasmicSequence AnalysisAdd
BLAST
Transmembranei237 – 26024Helical; Name=6Sequence AnalysisAdd
BLAST
Topological domaini261 – 27212ExtracellularSequence AnalysisAdd
BLAST
Transmembranei273 – 29220Helical; Name=7Sequence AnalysisAdd
BLAST
Topological domaini293 – 33341CytoplasmicSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 333333Olfactory receptor 1078PRO_0000150872Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi5 – 51N-linked (GlcNAc...)Sequence Analysis
Disulfide bondi97 ↔ 189PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Expressioni

Tissue specificityi

Olfactory epithelium.

Gene expression databases

GenevestigatoriP23265.

Structurei

3D structure databases

ProteinModelPortaliP23265.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG017625.
InParanoidiP23265.
KOiK04257.
PhylomeDBiP23265.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23265-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSSNRTRVS EFLLLGFVEN KDLQPLIYGL FLSMYLVTVI GNISIIVAII
60 70 80 90 100
SDPCLHTPMY FFLSNLSFVD ICFISTTVPK MLVNIQTQNN VITYAGCITQ
110 120 130 140 150
IYFFLLFVEL DNFLLTIMAY DRYVAICHPM HYTVIMNYKL CGFLVLVSWI
160 170 180 190 200
VSVLHALFQS LMMLALPFCT HLEIPHYFCE PNQVIQLTCS DAFLNDLVIY
210 220 230 240 250
FTLVLLATVP LAGIFYSYFK IVSSICAISS VHGKYKAFST CASHLSVVSL
260 270 280 290 300
FYCTGLGVYL SSAANNSSQA SATASVMYTV VTPMVNPFIY SLRNKDVKSV
310 320 330
LKKTLCEEVI RSPPSLLHFF LVLCHLPCFI FCY
Length:333
Mass (Da):37,541
Last modified:November 1, 1991 - v1
Checksum:i918AD817099ECCA3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64376 mRNA. Translation: AAA41739.1.
PIRiA23701.
RefSeqiNP_997480.1. NM_207597.1.
UniGeneiRn.120045.

Genome annotation databases

GeneIDi299593.
KEGGirno:299593.
UCSCiRGD:1333657. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M64376 mRNA. Translation: AAA41739.1 .
PIRi A23701.
RefSeqi NP_997480.1. NM_207597.1.
UniGenei Rn.120045.

3D structure databases

ProteinModelPortali P23265.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 299593.
KEGGi rno:299593.
UCSCi RGD:1333657. rat.

Organism-specific databases

CTDi 299593.
RGDi 1333657. Olr1078.

Phylogenomic databases

HOVERGENi HBG017625.
InParanoidi P23265.
KOi K04257.
PhylomeDBi P23265.

Miscellaneous databases

NextBioi 645440.

Gene expression databases

Genevestigatori P23265.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view ]
PRINTSi PR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A novel multigene family may encode odorant receptors: a molecular basis for odor recognition."
    Buck L., Axel R.
    Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiO1078_RAT
AccessioniPrimary (citable) accession number: P23265
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 29, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3