P23265 (O1078_RAT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Olfactory receptor 1078

Alternative name(s):
Olfactory receptor-like protein F3

Gene names

Name:

Olr1078

Organism

Rattus norvegicus (Rat) [Reference proteome]

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	333 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Odorant receptor Potential.
Subcellular location	Cell membrane; Multi-pass membrane protein.
Tissue specificity	Olfactory epithelium.
Sequence similarities	Belongs to the G-protein coupled receptor 1 family.

Ontologies

Keywords
Biological process	Olfaction Sensory transduction
Cellular component	Cell membrane Membrane
Domain	Transmembrane Transmembrane helix
Molecular function	G-protein coupled receptor Receptor Transducer
PTM	Disulfide bond Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	detection of chemical stimulus involved in sensory perception of smell Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	G-protein coupled receptor activity Inferred from electronic annotation. Source: UniProtKB-KW olfactory receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 333	333	Olfactory receptor 1078		PRO_0000150872
Regions
	Topological domain	1 – 25	25	Extracellular Potential
	Transmembrane	26 – 50	25	Helical; Name=1; Potential
	Topological domain	51 – 57	7	Cytoplasmic Potential
	Transmembrane	58 – 79	22	Helical; Name=2; Potential
	Topological domain	80 – 100	21	Extracellular Potential
	Transmembrane	101 – 120	20	Helical; Name=3; Potential
	Topological domain	121 – 139	19	Cytoplasmic Potential
	Transmembrane	140 – 158	19	Helical; Name=4; Potential
	Topological domain	159 – 196	38	Extracellular Potential
	Transmembrane	197 – 219	23	Helical; Name=5; Potential
	Topological domain	220 – 236	17	Cytoplasmic Potential
	Transmembrane	237 – 260	24	Helical; Name=6; Potential
	Topological domain	261 – 272	12	Extracellular Potential
	Transmembrane	273 – 292	20	Helical; Name=7; Potential
	Topological domain	293 – 333	41	Cytoplasmic Potential
Amino acid modifications
	Glycosylation	5	1	N-linked (GlcNAc...) Potential
	Disulfide bond	97 ↔ 189		By similarity

Sequences

	Sequence		Length	Mass (Da)
	P23265 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 918AD817099ECCA3	FASTA	333	37,541
	10 20 30 40 50 60 MDSSNRTRVS EFLLLGFVEN KDLQPLIYGL FLSMYLVTVI GNISIIVAII SDPCLHTPMY 70 80 90 100 110 120 FFLSNLSFVD ICFISTTVPK MLVNIQTQNN VITYAGCITQ IYFFLLFVEL DNFLLTIMAY 130 140 150 160 170 180 DRYVAICHPM HYTVIMNYKL CGFLVLVSWI VSVLHALFQS LMMLALPFCT HLEIPHYFCE 190 200 210 220 230 240 PNQVIQLTCS DAFLNDLVIY FTLVLLATVP LAGIFYSYFK IVSSICAISS VHGKYKAFST 250 260 270 280 290 300 CASHLSVVSL FYCTGLGVYL SSAANNSSQA SATASVMYTV VTPMVNPFIY SLRNKDVKSV 310 320 330 LKKTLCEEVI RSPPSLLHFF LVLCHLPCFI FCY

References

[1]	"A novel multigene family may encode odorant receptors: a molecular basis for odor recognition." Buck L., Axel R. Cell 65:175-187(1991) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M64376 mRNA. Translation: AAA41739.1.
IPI	IPI00209146.
PIR	A23701.
RefSeq	NP_997480.1. NM_207597.1.
UniGene	Rn.120045.
3D structure databases
ProteinModelPortal	P23265.
ModBase	Search...
Protein family/group databases
GPCRDB	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	299593.
KEGG	rno:299593.
UCSC	RGD:1333657. rat.
Organism-specific databases
CTD	299593.
RGD	1333657. Olr1078.
Phylogenomic databases
HOVERGEN	HBG017625.
KO	K04257.
Gene expression databases
Genevestigator	P23265.
Family and domain databases
InterPro	IPR000276. GPCR_Rhodpsn. IPR017452. GPCR_Rhodpsn_7TM. IPR000725. Olfact_rcpt. [Graphical view]
PANTHER	PTHR24236. PTHR24236. 1 hit.
PRINTS	PR00237. GPCRRHODOPSN. PR00245. OLFACTORYR.
PROSITE	PS00237. G_PROTEIN_RECEP_F1_1. 1 hit. PS50262. G_PROTEIN_RECEP_F1_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	645440.

Entry information

Entry name

O1078_RAT

Accession

Primary (citable) accession number: P23265

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	May 1, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program