Reviewed, UniProtKB/Swiss-Prot P23180 (YHC1_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized oxidoreductase YHL021C
    EC=1.14.11.-

Gene names

Ordered Locus Names:

YHL021C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	465 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Cofactor	Iron By similarity. Ascorbate By similarity.
Miscellaneous	Present with 5800 molecules/cell in log phase SD medium. Ref.3
Sequence similarities	Belongs to the gamma-BBH/TMLD family.

Ontologies

Keywords
Ligand	Iron
Molecular function	Dioxygenase Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrion Inferred from direct assay. Source: SGD
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: UniProtKB-KW oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen Inferred from electronic annotation. Source: UniProtKB-KW protein binding Inferred from physical interaction. Source: IntAct
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
PCP1	P53259	1	EBI-24332,EBI-23242

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 465	465	Uncharacterized oxidoreductase YHL021C		PRO_0000207092

Sequences

	Sequence		Length	Mass (Da)
	P23180-1 [UniParc]. Last modified February 1, 1995. Version 2. Checksum: 568B17051DB60899	FASTA	465	53,135
	10 20 30 40 50 60 MLRSNLCRGS RILARLTTTP RTYTSAATAA AANRGHIIKT YFNRDSTTIT FSMEESSKPV 70 80 90 100 110 120 SVCFNNVFLR DASHSAKLVT TGELYHNEKL TAPQDIQISE DGKSLVVKWK DGGHHQFPLQ 130 140 150 160 170 180 FFIDYKGSSF VSPATRKQES RYRPQLWNKR ILKDNVKDLL SVSYNEFIDP KDDSKLFQTL 190 200 210 220 230 240 VNLQKFGIAF ISGTPSSSSE GLTIQKICER IGPIRSTVHG EGTFDVNASQ ATSVNAHYAN 250 260 270 280 290 300 KDLPLHTDLP FLENVPGFQI LQSLPATEGE DPNTRPMNYF VDAFYATRNV RESDFEAYEA 310 320 330 340 350 360 LQIVPVNYIY ENGDKRYYQS KPLIEHHDIN EDNTLLGNYE ALIKCINYSP PYQAPFTFGI 370 380 390 400 410 420 YDKPSDLNNN LDLNLITTPA KLTERFLFKS FIRGLNLFES HINDFNNQFR LQLPENCCVI 430 440 450 460 FNNRRILHAN SLTSSNQQWL KGCYFDSDTF KSKLKFLEEK FPHDK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII." Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Dover J., Du Z., Favello A., Fulton L., Gattung S., Geisel C., Kirsten J., Kucaba T., Hillier L.W., Jier M., Johnston L., Langston Y., Latreille P. , Louis E.J., Macri C., Mardis E., Menezes S., Mouser L., Nhan M., Rifkin L., Riles L., St Peter H., Trevaskis E., Vaughan K., Vignati D., Wilcox L., Wohldman P., Waterston R., Wilson R., Vaudin M. Science 265:2077-2082(1994) [PubMed: 8091229] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"Isolation, DNA sequence, and regulation of a meiosis-specific eukaryotic recombination gene." Atcheson C.L., Didomenico B., Frackman S., Esposito R.E., Elder R.T. Proc. Natl. Acad. Sci. U.S.A. 84:8035-8039(1987) [PubMed: 3317399] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 366-465.
[3]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	U11582 Genomic DNA. Translation: AAB65074.1. J02987 Genomic DNA. Translation: AAA65531.1.
PIR	S46835.
RefSeq	NP_011842.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4919N.
IntAct	P23180. 8 interactions.
STRING	P23180.
Proteomic databases
PeptideAtlas	P23180.
Genome annotation databases
Ensembl	YHL021C; YHL021C; YHL021C; Saccharomyces cerevisiae. [Genome view]
GeneID	856365.
GenomeReviews	Gene locus YHL021C in contig U00093_GR.
KEGG	sce:YHL021C.
NMPDR	fig|4932.3.peg.2980.
Organism-specific databases
CYGD	YHL021c.
SGD	S000001013. YHL021C.
Phylogenomic databases
HOGENOM	P23180.
OMA	LYYESPP.
Gene expression databases
ArrayExpress	P23180.
Genevestigator	P23180.
GermOnline	YHL021C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR003819. Taurine_dOase. [Graphical view]
Pfam	PF02668. TauD. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	981831.

Entry information

Entry name

YHC1_YEAST

Accession

Primary (citable) accession number: P23180

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	February 1, 1995
Last modified:	November 3, 2009
This is version 67 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)