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P23170

- 25KD_SARPE

UniProt

P23170 - 25KD_SARPE

Protein

Development-specific 25 kDa protein

Gene
N/A
Organism
Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 66 (01 Oct 2014)
      Sequence version 1 (01 Nov 1991)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei138 – 1381SubstrateBy similarity
    Active sitei151 – 1511Proton acceptorPROSITE-ProRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 3425NAD or NADPBy similarityAdd
    BLAST

    GO - Molecular functioni

    1. alcohol dehydrogenase (NAD) activity Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Development-specific 25 kDa protein
    OrganismiSarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
    Taxonomic identifieri7386 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaSarcophagidaeSarcophagaBoettcherisca

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 258258Development-specific 25 kDa proteinPRO_0000054445Add
    BLAST

    Expressioni

    Developmental stagei

    Expressed in the fat body of middle third-instar larvae.

    Structurei

    3D structure databases

    ProteinModelPortaliP23170.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR002426. ADH_Ceratitis-type.
    IPR002424. ADH_insect.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view]
    PfamiPF00106. adh_short. 1 hit.
    [Graphical view]
    PRINTSiPR01169. CERATITISADH.
    PR01167. INSADHFAMILY.
    PR00080. SDRFAMILY.
    PROSITEiPS00061. ADH_SHORT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P23170-1 [UniParc]FASTAAdd to Basket

    « Hide

    MMDWNNKNVV YVGGFSGFGY QVCQMMMKKP MKHLIVCSRM ENVEMLKKLQ    50
    AINTSVKVMF VQMNIADYAS IVKGVKQVIG HVGHVDVLIN GVGGLADKDV 100
    ETTVAVNLTG LINTTLMFMP YMDKTQSGHG GMVVSISSVY GLEPGPAFSV 150
    YSAAKHGGIG FTRSMADEHL YHKTGVAFMC ICPAMTSTEL MMNKRDMNWM 200
    KWVPHSEEMW KMVMDAKMQT PEECAVNMMT AMEQAKNGAI YICSTSGMKE 250
    ITPTVYMH 258
    Length:258
    Mass (Da):28,633
    Last modified:November 1, 1991 - v1
    Checksum:i651CB188A5D1547A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X02570 Genomic DNA. Translation: CAA26412.1.
    PIRiA24181.
    T11741.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X02570 Genomic DNA. Translation: CAA26412.1 .
    PIRi A24181.
    T11741.

    3D structure databases

    ProteinModelPortali P23170.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR002426. ADH_Ceratitis-type.
    IPR002424. ADH_insect.
    IPR002198. DH_sc/Rdtase_SDR.
    IPR016040. NAD(P)-bd_dom.
    IPR020904. Sc_DH/Rdtase_CS.
    [Graphical view ]
    Pfami PF00106. adh_short. 1 hit.
    [Graphical view ]
    PRINTSi PR01169. CERATITISADH.
    PR01167. INSADHFAMILY.
    PR00080. SDRFAMILY.
    PROSITEi PS00061. ADH_SHORT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structural analysis of a developmentally regulated 25-kDa protein gene of Sarcophaga peregrina."
      Matsumoto N., Sekimizu K., Soma G., Ohmura Y., Andoh T., Nakanishi Y., Obinata M., Natori S.
      J. Biochem. 97:1501-1508(1985) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Purification and cDNA cloning of the alcohol dehydrogenase of the flesh fly Sarcophaga peregrina. A structural relationship between alcohol dehydrogenase and a 25-kDa protein."
      Horio T., Kubo T., Natori S.
      Eur. J. Biochem. 237:698-703(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION.

    Entry informationi

    Entry namei25KD_SARPE
    AccessioniPrimary (citable) accession number: P23170
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1991
    Last sequence update: November 1, 1991
    Last modified: October 1, 2014
    This is version 66 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3