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P23170 (25KD_SARPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Development-specific 25 kDa protein
OrganismSarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
Taxonomic identifier7386 [NCBI]
Taxonomic lineageEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaSarcophagidaeSarcophagaBoettcherisca

Protein attributes

Sequence length258 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Developmental stage

Expressed in the fat body of middle third-instar larvae.

Sequence similarities

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Ontologies

Keywords
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Molecular_functionalcohol dehydrogenase (NAD) activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 258258Development-specific 25 kDa protein
PRO_0000054445

Regions

Nucleotide binding10 – 3425NAD or NADP By similarity

Sites

Active site1511Proton acceptor By similarity
Binding site1381Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
P23170 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 651CB188A5D1547A

FASTA25828,633
        10         20         30         40         50         60 
MMDWNNKNVV YVGGFSGFGY QVCQMMMKKP MKHLIVCSRM ENVEMLKKLQ AINTSVKVMF 

        70         80         90        100        110        120 
VQMNIADYAS IVKGVKQVIG HVGHVDVLIN GVGGLADKDV ETTVAVNLTG LINTTLMFMP 

       130        140        150        160        170        180 
YMDKTQSGHG GMVVSISSVY GLEPGPAFSV YSAAKHGGIG FTRSMADEHL YHKTGVAFMC 

       190        200        210        220        230        240 
ICPAMTSTEL MMNKRDMNWM KWVPHSEEMW KMVMDAKMQT PEECAVNMMT AMEQAKNGAI 

       250 
YICSTSGMKE ITPTVYMH 

« Hide

References

[1]"Structural analysis of a developmentally regulated 25-kDa protein gene of Sarcophaga peregrina."
Matsumoto N., Sekimizu K., Soma G., Ohmura Y., Andoh T., Nakanishi Y., Obinata M., Natori S.
J. Biochem. 97:1501-1508(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Purification and cDNA cloning of the alcohol dehydrogenase of the flesh fly Sarcophaga peregrina. A structural relationship between alcohol dehydrogenase and a 25-kDa protein."
Horio T., Kubo T., Natori S.
Eur. J. Biochem. 237:698-703(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: SEQUENCE REVISION.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X02570 Genomic DNA. Translation: CAA26412.1.
PIRA24181.
T11741.

3D structure databases

ProteinModelPortalP23170.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR002426. ADH_Ceratitis-type.
IPR002424. ADH_insect.
IPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSPR01169. CERATITISADH.
PR01167. INSADHFAMILY.
PR00080. SDRFAMILY.
PROSITEPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry name25KD_SARPE
AccessionPrimary (citable) accession number: P23170
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: May 29, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families