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P23170

- 25KD_SARPE

UniProt

P23170 - 25KD_SARPE

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Protein

Development-specific 25 kDa protein

Gene
N/A
Organism
Sarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei138 – 1381SubstrateBy similarity
Active sitei151 – 1511Proton acceptorPROSITE-ProRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 3425NAD or NADPBy similarityAdd
BLAST

GO - Molecular functioni

  1. alcohol dehydrogenase (NAD) activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Development-specific 25 kDa protein
OrganismiSarcophaga peregrina (Flesh fly) (Boettcherisca peregrina)
Taxonomic identifieri7386 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraEndopterygotaDipteraBrachyceraMuscomorphaOestroideaSarcophagidaeSarcophagaBoettcherisca

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 258258Development-specific 25 kDa proteinPRO_0000054445Add
BLAST

Expressioni

Developmental stagei

Expressed in the fat body of middle third-instar larvae.

Structurei

3D structure databases

ProteinModelPortaliP23170.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR002426. ADH_Ceratitis-type.
IPR002424. ADH_insect.
IPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view]
PfamiPF00106. adh_short. 1 hit.
[Graphical view]
PRINTSiPR01169. CERATITISADH.
PR01167. INSADHFAMILY.
PR00080. SDRFAMILY.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P23170-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMDWNNKNVV YVGGFSGFGY QVCQMMMKKP MKHLIVCSRM ENVEMLKKLQ
60 70 80 90 100
AINTSVKVMF VQMNIADYAS IVKGVKQVIG HVGHVDVLIN GVGGLADKDV
110 120 130 140 150
ETTVAVNLTG LINTTLMFMP YMDKTQSGHG GMVVSISSVY GLEPGPAFSV
160 170 180 190 200
YSAAKHGGIG FTRSMADEHL YHKTGVAFMC ICPAMTSTEL MMNKRDMNWM
210 220 230 240 250
KWVPHSEEMW KMVMDAKMQT PEECAVNMMT AMEQAKNGAI YICSTSGMKE

ITPTVYMH
Length:258
Mass (Da):28,633
Last modified:November 1, 1991 - v1
Checksum:i651CB188A5D1547A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X02570 Genomic DNA. Translation: CAA26412.1.
PIRiA24181.
T11741.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X02570 Genomic DNA. Translation: CAA26412.1 .
PIRi A24181.
T11741.

3D structure databases

ProteinModelPortali P23170.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR002426. ADH_Ceratitis-type.
IPR002424. ADH_insect.
IPR002198. DH_sc/Rdtase_SDR.
IPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
[Graphical view ]
Pfami PF00106. adh_short. 1 hit.
[Graphical view ]
PRINTSi PR01169. CERATITISADH.
PR01167. INSADHFAMILY.
PR00080. SDRFAMILY.
PROSITEi PS00061. ADH_SHORT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structural analysis of a developmentally regulated 25-kDa protein gene of Sarcophaga peregrina."
    Matsumoto N., Sekimizu K., Soma G., Ohmura Y., Andoh T., Nakanishi Y., Obinata M., Natori S.
    J. Biochem. 97:1501-1508(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Purification and cDNA cloning of the alcohol dehydrogenase of the flesh fly Sarcophaga peregrina. A structural relationship between alcohol dehydrogenase and a 25-kDa protein."
    Horio T., Kubo T., Natori S.
    Eur. J. Biochem. 237:698-703(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION.

Entry informationi

Entry namei25KD_SARPE
AccessioniPrimary (citable) accession number: P23170
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 1, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3