P23160 (R34K_CLOPA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: 34.2 kDa protein in rubredoxin operon EC=1.8.1.- Alternative name(s): ORF A
Organism	Clostridium pasteurianum
Taxonomic identifier	1501 [NCBI]
Taxonomic lineage	Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	308 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.

Ontologies

Keywords
Domain	Redox-active center
Ligand	FAD Flavoprotein NAD NADP
Molecular function	Oxidoreductase
PTM	Disulfide bond
Gene Ontology (GO)
Biological process	removal of superoxide radicals Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro thioredoxin-disulfide reductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 308	308	34.2 kDa protein in rubredoxin operon		PRO_0000166790
Regions
	Nucleotide binding	268 – 278	11	FAD By similarity
Amino acid modifications
	Disulfide bond	136 ↔ 139		Redox-active By similarity

Sequences

	Sequence		Length	Mass (Da)
	P23160 [UniParc]. Last modified November 1, 1991. Version 1. Checksum: 52D9CF51208EFC37	FASTA	308	34,215
	10 20 30 40 50 60 MKEEKQLDLV IIGAGPAGLT AAIYAIRAKL NTLVLENELV GGQIRETYTV ENFPGFNVIS 70 80 90 100 110 120 GADLADKMEE HAASIGVNID QFSNIEKIKL SDDEKIIETE DVIYKVKALI IATGAKSRRL 130 140 150 160 170 180 PIPEEEKLHG KVIHYCELCD GALYQGKDLV VVGGGNSAVE AAIFLTKYAR NITIVHQFDY 190 200 210 220 230 240 LQAQKYSQDE LFKHKNVKII WDSEIRNIVG ENEIEKIVVE NVKTKQKTEL KADGVFVYIG 250 260 270 280 290 300 YEPKTELFKD SININKWGYI ETDENMETNI KGVFAAGDVR SKLIRQLTTA VSDGTVAALM AEKYIGGK

References

[1]	"Cloning, sequencing and expression in Escherichia coli of the rubredoxin gene from Clostridium pasteurianum." Mathieu I., Meyer J., Moulis J.-M. Biochem. J. 285:255-262(1992) [PubMed: 1637309] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	M60116 Genomic DNA. Translation: AAA23276.1.
PIR	S29117.
3D structure databases
ProteinModelPortal	P23160.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR008255. Pyr_nucl-diS_OxRdtase_2_AS. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR001327. Pyr_OxRdtase_NAD-bd_dom. IPR000103. Pyridine_nuc-diS_OxRdtase_2. IPR005982. Thioredox_Rdtase. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
TIGRFAMs	TIGR01292. TRX_reduct. 1 hit.
PROSITE	PS00573. PYRIDINE_REDOX_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

R34K_CLOPA

Accession

Primary (citable) accession number: P23160

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1991
Last sequence update:	November 1, 1991
Last modified:	September 21, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program