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P23146 (LUXA2_PHOLU) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alkanal monooxygenase alpha chain

EC=1.14.14.3
Alternative name(s):
Bacterial luciferase alpha chain
Gene names
Name:luxA
OrganismPhotorhabdus luminescens (Xenorhabdus luminescens)
Taxonomic identifier29488 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePhotorhabdus

Protein attributes

Sequence length362 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Light-emitting reaction in luminous bacteria.

Catalytic activity

RCHO + reduced FMN + O2 = RCOOH + FMN + H2O + light.

Subunit structure

Heterodimer of an alpha and a beta chain.

Miscellaneous

The synthesis of this protein is regulated by a complex control mechanism that has been termed autoinduction.

Sequence similarities

Belongs to the bacterial luciferase oxidoreductase family.

Ontologies

Keywords
   Biological processLuminescence
   LigandFlavoprotein
FMN
   Molecular functionMonooxygenase
Oxidoreductase
Photoprotein
Gene Ontology (GO)
   Biological_processbioluminescence

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionalkanal monooxygenase (FMN-linked) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 362362Alkanal monooxygenase alpha chain
PRO_0000220168

Sequences

Sequence LengthMass (Da)Tools
P23146 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 6F9033401D296416

FASTA36241,401
        10         20         30         40         50         60 
MKFGNFLLTY QPPQFSQTEV MKWLVKLGRI SEECGFDTVW LLEHHFTEFG LLGNPYVAAA 

        70         80         90        100        110        120 
YLLGATKKLN VGTAAIVLPT AHPVRQLEEV NLLDQMSKGR FRFGICRGLY NKDFRVFGTD 

       130        140        150        160        170        180 
MNNSRALMEC WYKLIRNGMT EGYMEADNEH IKFHKVKVLP TAYSQGGAPI YVVAESASTT 

       190        200        210        220        230        240 
EWAAQHGLPM ILSWIINTND KKAQIELYNE VAQEYGHDIH NIDHCLSYIT SVDHDSMKAK 

       250        260        270        280        290        300 
EICRNFLGHW YDSYVNATTI FDDSDKTKGY DFNKGQWRDF VLKGHKNTNR RVDYSYEINP 

       310        320        330        340        350        360 
VGTPQECIDI IQTDIDATGI SNICCGFEAN GTVDEIISSM KLFQSDVMPF LKEKQQFSYY 


IS 

« Hide

References

[1]"Cloning and nucleotide sequences of lux genes and characterization of luciferase of Xenorhabdus luminescens from a human wound."
Xi L., Cho K.W., Tu S.C.
J. Bacteriol. 173:1399-1405(1991) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Hw.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M62917 Genomic DNA. Translation: AAA63565.1.
PIRC38448.

3D structure databases

ProteinModelPortalP23146.
SMRP23146. Positions 1-355.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.30. 1 hit.
InterProIPR018235. Bacterial_luciferase_CS.
IPR011251. Luciferase-like_dom.
IPR002103. Luciferase_bac.
[Graphical view]
PfamPF00296. Bac_luciferase. 1 hit.
[Graphical view]
PRINTSPR00089. LUCIFERASE.
SUPFAMSSF51679. SSF51679. 1 hit.
PROSITEPS00494. BACTERIAL_LUCIFERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameLUXA2_PHOLU
AccessionPrimary (citable) accession number: P23146
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: October 16, 2013
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families