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P23060 (MAK32_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein MAK32
Alternative name(s):
Maintenance of killer protein 32
Gene names
Name:MAK32
Ordered Locus Names:YCR019W
ORF Names:YCR19W
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Function

Necessary for the structural stability of L-A double-stranded RNA-containing particles. Necessary for growth at 37 degrees Celsius as well as for maintenance of the killer plasmid.

Sequence similarities

To S.pombe SpAC4G8.14c.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 363363Protein MAK32
PRO_0000084555

Experimental info

Sequence conflict151I → II Ref.1
Sequence conflict821Missing Ref.1

Sequences

Sequence LengthMass (Da)Tools
P23060 [UniParc].

Last modified May 1, 1992. Version 2.
Checksum: CFB358F8ACF6EA4C

FASTA36340,783
        10         20         30         40         50         60 
MMNEEDSTET KSLVITNGMF IIDDIERSKY NIHYKNVPGG GGTFAILGAC IISSGNVTSK 

        70         80         90        100        110        120 
GLKWIVDRGS DFPKEVIREI DSWGTDVRFR DDFSRLTTKG LNYYEGSDDL RKFKFLTPKK 

       130        140        150        160        170        180 
QINVDDWIST FGQKIIDEMH AFHLLCSGSR CLDIINDLLR VKSSKGTKPI VIWEPFPDLC 

       190        200        210        220        230        240 
DFDHQNDIKS VMQRNDVTVI LSPNAEESSR LFGLSSKEPT SLEECLALAH RFDDFMDENN 

       250        260        270        280        290        300 
MCILRCGALG SISVSEKFKN GRTYDHFPAY HFKTQSKVLD PTGGGNSFLG GFAVSYALTK 

       310        320        330        340        350        360 
SLDIASICGN IAAGAIIEQF GIPRYDPIAK TWNGITFLDR LKFYLSQSGL QYNINDLYKS 


LTR 

« Hide

References

« Hide 'large scale' references
[1]"The PET18 locus of Saccharomyces cerevisiae: a complex locus containing multiple genes."
Toh-e A., Sahashi Y.
Yeast 1:159-171(1985) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The complete DNA sequence of yeast chromosome III."
Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M. expand/collapse author list , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae."
Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. expand/collapse author list , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J.
Genome Res. 17:536-543(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X59720 Genomic DNA. Translation: CAA42310.1.
AY693011 Genomic DNA. Translation: AAT93030.1.
BK006937 Genomic DNA. Translation: DAA07496.1.
PIRBVBYK2. S19429.
RefSeqNP_009946.1. NM_001178732.1.

3D structure databases

ProteinModelPortalP23060.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid31000. 16 interactions.
IntActP23060. 1 interaction.
STRING4932.YCR019W.

Proteomic databases

PaxDbP23060.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYCR019W; YCR019W; YCR019W.
GeneID850381.
KEGGsce:YCR019W.

Organism-specific databases

CYGDYCR019w.
SGDS000000612. MAK32.

Phylogenomic databases

eggNOGCOG0524.
HOGENOMHOG000206193.
OMAWIVDQGS.
OrthoDBEOG7P02VD.

Enzyme and pathway databases

BioCycYEAST:G3O-29334-MONOMER.

Gene expression databases

GenevestigatorP23060.

Family and domain databases

InterProIPR011611. PfkB_dom.
[Graphical view]
PfamPF00294. PfkB. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio965885.

Entry information

Entry nameMAK32_YEAST
AccessionPrimary (citable) accession number: P23060
Secondary accession number(s): D6VR27
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: May 1, 1992
Last modified: February 19, 2014
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome III

Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD