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Protein

Protein MAK32

Gene

MAK32

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Necessary for the structural stability of L-A double-stranded RNA-containing particles. Necessary for growth at 37 degrees Celsius as well as for maintenance of the killer plasmid.

GO - Biological processi

  1. interspecies interaction between organisms Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29334-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein MAK32
Alternative name(s):
Maintenance of killer protein 32
Gene namesi
Name:MAK32
Ordered Locus Names:YCR019W
ORF Names:YCR19W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome III

Organism-specific databases

CYGDiYCR019w.
SGDiS000000612. MAK32.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 363363Protein MAK32PRO_0000084555Add
BLAST

Proteomic databases

MaxQBiP23060.
PaxDbiP23060.

Expressioni

Gene expression databases

GenevestigatoriP23060.

Interactioni

Protein-protein interaction databases

BioGridi31000. 16 interactions.
IntActiP23060. 1 interaction.
STRINGi4932.YCR019W.

Structurei

3D structure databases

ProteinModelPortaliP23060.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

To S.pombe SpAC4G8.14c.Curated

Phylogenomic databases

eggNOGiCOG0524.
HOGENOMiHOG000206193.
InParanoidiP23060.
OMAiWIVDQGS.
OrthoDBiEOG7P02VD.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
SUPFAMiSSF53613. SSF53613. 1 hit.

Sequencei

Sequence statusi: Complete.

P23060-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNEEDSTET KSLVITNGMF IIDDIERSKY NIHYKNVPGG GGTFAILGAC
60 70 80 90 100
IISSGNVTSK GLKWIVDRGS DFPKEVIREI DSWGTDVRFR DDFSRLTTKG
110 120 130 140 150
LNYYEGSDDL RKFKFLTPKK QINVDDWIST FGQKIIDEMH AFHLLCSGSR
160 170 180 190 200
CLDIINDLLR VKSSKGTKPI VIWEPFPDLC DFDHQNDIKS VMQRNDVTVI
210 220 230 240 250
LSPNAEESSR LFGLSSKEPT SLEECLALAH RFDDFMDENN MCILRCGALG
260 270 280 290 300
SISVSEKFKN GRTYDHFPAY HFKTQSKVLD PTGGGNSFLG GFAVSYALTK
310 320 330 340 350
SLDIASICGN IAAGAIIEQF GIPRYDPIAK TWNGITFLDR LKFYLSQSGL
360
QYNINDLYKS LTR
Length:363
Mass (Da):40,783
Last modified:May 1, 1992 - v2
Checksum:iCFB358F8ACF6EA4C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti15 – 151I → II (PubMed:3916862).Curated
Sequence conflicti82 – 821Missing (PubMed:3916862).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42310.1.
AY693011 Genomic DNA. Translation: AAT93030.1.
BK006937 Genomic DNA. Translation: DAA07496.1.
PIRiS19429. BVBYK2.
RefSeqiNP_009946.1. NM_001178732.1.

Genome annotation databases

EnsemblFungiiYCR019W; YCR019W; YCR019W.
GeneIDi850381.
KEGGisce:YCR019W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X59720 Genomic DNA. Translation: CAA42310.1.
AY693011 Genomic DNA. Translation: AAT93030.1.
BK006937 Genomic DNA. Translation: DAA07496.1.
PIRiS19429. BVBYK2.
RefSeqiNP_009946.1. NM_001178732.1.

3D structure databases

ProteinModelPortaliP23060.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31000. 16 interactions.
IntActiP23060. 1 interaction.
STRINGi4932.YCR019W.

Proteomic databases

MaxQBiP23060.
PaxDbiP23060.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYCR019W; YCR019W; YCR019W.
GeneIDi850381.
KEGGisce:YCR019W.

Organism-specific databases

CYGDiYCR019w.
SGDiS000000612. MAK32.

Phylogenomic databases

eggNOGiCOG0524.
HOGENOMiHOG000206193.
InParanoidiP23060.
OMAiWIVDQGS.
OrthoDBiEOG7P02VD.

Enzyme and pathway databases

BioCyciYEAST:G3O-29334-MONOMER.

Miscellaneous databases

NextBioi965885.

Gene expression databases

GenevestigatoriP23060.

Family and domain databases

Gene3Di3.40.1190.20. 1 hit.
InterProiIPR011611. PfkB_dom.
IPR029056. Ribokinase-like.
[Graphical view]
PfamiPF00294. PfkB. 1 hit.
[Graphical view]
SUPFAMiSSF53613. SSF53613. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The PET18 locus of Saccharomyces cerevisiae: a complex locus containing multiple genes."
    Toh-e A., Sahashi Y.
    Yeast 1:159-171(1985) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The complete DNA sequence of yeast chromosome III."
    Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M., Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G., Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A., Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M.
    , Carcano C., Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M., Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C., Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F., Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C., Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E., Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P., Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J., Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P., Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M., Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P., Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G., Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E., Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F., Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L., Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J., Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M., Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A., Richterich P., Roberts A.B., Rodriguez F., Sanz E., Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J., Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I., Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M., Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M., Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D., Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K., Sgouros J.G.
    Nature 357:38-46(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.

Entry informationi

Entry nameiMAK32_YEAST
AccessioniPrimary (citable) accession number: P23060
Secondary accession number(s): D6VR27
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: May 1, 1992
Last modified: January 7, 2015
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  2. Yeast chromosome III
    Yeast (Saccharomyces cerevisiae) chromosome III: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.