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Reviewed, UniProtKB/Swiss-Prot P23014 (F16PA_XANFL)

Last modified June 16, 2009. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Fructose-1,6-bisphosphatase class 1
      Short name=FBPase class 1
    EC=3.1.3.11
Alternative name(s):
    D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Gene names
Name: fbp
Synonyms: cbbF, cfxF
OrganismXanthobacter flavus
Taxonomic identifier281 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Xanthobacteraceae › Xanthobacter

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Protein attributes

Sequence length364 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. HAMAP MF_01855

Cofactor

Binds 2 magnesium ions per subunit By similarity.

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_01855

Subunit structure

Homotetramer By similarity.

Subcellular location

Cytoplasm Potential.

Sequence similarities

Belongs to the FBPase class 1 family.

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Ontologies

Keywords
   Biological processCarbohydrate metabolism
   Cellular componentCytoplasm
   LigandMagnesium
Metal-binding
   Molecular functionHydrolase
Gene Ontology (GO)
   Biological processcarbohydrate biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionfructose 1,6-bisphosphate 1-phosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 364364Fructose-1,6-bisphosphatase class 1 HAMAP MF_01855
PRO_0000200491

Regions

Region130 – 1334Substrate binding By similarity
Region273 – 2753Substrate binding By similarity

Sites

Metal binding1081Magnesium 1 By similarity
Metal binding1271Magnesium 1 By similarity
Metal binding1271Magnesium 2 By similarity
Metal binding1291Magnesium 1; via carbonyl oxygen By similarity
Metal binding1301Magnesium 2 By similarity
Metal binding2931Magnesium 2 By similarity
Binding site2211Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
P23014-1 [UniParc].

Last modified November 1, 1991. Version 1.
Checksum: 2FEC9827954B47C7

FASTA36438,739
        10         20         30         40         50         60 
MLEPNADHRA AVAQAAGVAA SRITLTVMLD EWAGADARRR AVADTVCALA TGCASLAAAI 

        70         80         90        100        110        120 
AEGPLAGDLA RTLSSGEAGE GQKALDVISN DIVIGALKAA PVAAVASEEN DAPVLLDPTA 

       130        140        150        160        170        180 
PLLVAIDPLD GSSNIDTDIS VGTIFAVFPR PEGADASEPS AFLQNGRDML AAGYVIYGPH 

       190        200        210        220        230        240 
TAMMLTLGAG TWHFALDRAG LFRLVDAEVK VKEGAAEFAI NMSNYHHWDV PVRDYVDDCL 

       250        260        270        280        290        300 
AGKKGPRERD FNMRWVASMV ADAHRIFQRG GIYLYPGDGR KGYTHGRLRL LYEAFPVAFL 

       310        320        330        340        350        360 
MEQASGSATD GRGAILDLSA TGLHQRVPFI FGSRDEVARV SRYHLEPNGH GERSPLFARR 


GLFI

« Hide

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References

[1]"Nucleotide sequences of the genes encoding fructosebisphosphatase and phosphoribulokinase from Xanthobacter flavus H4-14."
Meijer W.G., Enequist H.G., Terpstra P., Dijkhuizen L.
J. Gen. Microbiol. 136:2225-2230(1990) [PubMed: 1964170] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: H4-14.
[2]"Identification and organization of carbon dioxide fixation genes in Xanthobacter flavus H4-14."
Meijer W.G., Arnberg A.C., Enequist H.G., Terpstra P., Lidstrom M.E., Dijkhuizen L.
Mol. Gen. Genet. 225:320-330(1991) [PubMed: 1900916] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: H4-14.

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Cross-references

Sequence databases

X17252 Genomic DNA. Translation: CAA35118.1.
PIRPAQXF. A45867.

3D structure databases

HSSPHSSP built from PDB template 1DBZ based on UniProtKB P46275.
ModBaseSearch...

Enzyme and pathway databases

BRENDA3.1.3.11. 2278.

Family and domain databases

HAMAPMF_01855.
[Tree]
InterProIPR000146. Fructose_bisphosphatase.
IPR017955. IMPase/FBPase.
[Graphical view]
PANTHERPTHR11556. In_FB_phphtase. 1 hit.
PfamPF00316. FBPase. 1 hit.
[Graphical view]
PRINTSPR00115. FBPHPHTASE.
PR00377. INFBPHPHTASE.
ProDomPD001491. In_FB_phphtase. 1 hit.
[Graphical view] [Entries sharing at least one domain]
PROSITEPS00124. FBPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameF16PA_XANFL
AccessionPrimary (citable) accession number: P23014
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1991
Last sequence update: November 1, 1991
Last modified: June 16, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents