Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Capsid protein

Gene

ORF4

Organism
Tobacco necrosis virus (strain A) (TNV-A)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 28 nm in diameter, and consisting of 180 capsid proteins.

GO - Molecular functioni

  1. RNA binding Source: UniProtKB-KW
  2. structural molecule activity Source: InterPro
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Capsid protein
Alternative name(s):
p30
Gene namesi
ORF Names:ORF4
OrganismiTobacco necrosis virus (strain A) (TNV-A)
Taxonomic identifieri12055 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageTombusviridaeAlphanecrovirus
Virus hostiChenopodium amaranticolor [TaxID: 66262]
Chenopodium quinoa (Quinoa) [TaxID: 63459]
Cucumis sativus (Cucumber) [TaxID: 3659]
Nicotiana clevelandii (Wild tobacco) [TaxID: 81866]
Nicotiana tabacum (Common tobacco) [TaxID: 4097]
Phaseolus vulgaris (Kidney bean) (French bean) [TaxID: 3885]
Tulipa gesneriana (Garden tulip) [TaxID: 13306]
ProteomesiUP000000575: Genome

Subcellular locationi

Virion Curated

GO - Cellular componenti

  1. T=3 icosahedral viral capsid Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Capsid protein, T=3 icosahedral capsid protein, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 276276Capsid proteinPRO_0000222869Add
BLAST

Interactioni

Subunit structurei

Homomultimer.Curated

Structurei

3D structure databases

ProteinModelPortaliP22959.
SMRiP22959. Positions 56-275.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1 – 8585R domain, interaction with RNAAdd
BLAST
Regioni86 – 266181S domain, virion shellAdd
BLAST
Regioni267 – 27610P domain, projecting

Sequence similaritiesi

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22959-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKKNNNNG QYIILRTPEQ QVEIDQRNAR RAQMGRMKKA RQPVQRYLQQ
60 70 80 90 100
HGLRNGLSGR GGYIVAPTSG GVVTRPIVPK FSNRGDSTIV RNTEILNNQI
110 120 130 140 150
LAALGAFNTT NSALIAAAPS WLASIADLYS KYRWLSCEII YIPKCPTTTS
160 170 180 190 200
GSIAMAFTYD RNDAAPTARA QLSQSYKAIN FPPYAGYDGA AYLNSNQGAG
210 220 230 240 250
SAIAVQLDVT KLDKPWYPTI SSAGFGALSV LDQNQFCPAS LVVASDGGPA
260 270
TATPAGDLFI KYVIEFIEPI NPTMNV
Length:276
Mass (Da):29,784
Last modified:August 1, 1991 - v1
Checksum:i44C505AE97F5892B
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti54 – 541R → Q.
Natural varianti71 – 711G → A.
Natural varianti115 – 1151I → T.
Natural varianti124 – 1241S → G.
Natural varianti193 – 1931L → S.
Natural varianti229 – 2291S → G.

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33002 Genomic RNA. Translation: AAA86437.1.
PIRiD35523. VCWQTN.
RefSeqiNP_056828.1. NC_001777.1.

Genome annotation databases

GeneIDi1493900.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M33002 Genomic RNA. Translation: AAA86437.1.
PIRiD35523. VCWQTN.
RefSeqiNP_056828.1. NC_001777.1.

3D structure databases

ProteinModelPortaliP22959.
SMRiP22959. Positions 56-275.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi1493900.

Family and domain databases

Gene3Di2.60.120.20. 1 hit.
InterProiIPR000937. Capsid_prot_S-dom_vir.
IPR029053. Viral_coat.
[Graphical view]
PfamiPF00729. Viral_coat. 1 hit.
[Graphical view]
PRINTSiPR00233. ICOSAHEDRAL.
PROSITEiPS00555. ICOSAH_VIR_COAT_S. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome structure of tobacco necrosis virus strain A."
    Meulewaeter F., Seurinck J., van Emmelo J.
    Virology 177:699-709(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiCAPSD_TNVA
AccessioniPrimary (citable) accession number: P22959
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: January 7, 2015
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.