P22949 - MCRB_METTE
Methyl-coenzyme M reductase subunit beta
Reviewed - <p>Annotation score: 3 out of 5</p> <div> <p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome.</p><p><a href='../manual/annotation_score' target='_top'>More...</a></p>Annotation score: 3 out of 5 - Experimental evidence at protein leveli
- Names & Taxonomy
- Subcellular locationSubcell. location
- Pathology & BiotechPathol./Biotech
- PTM / Processing
- Family & Domains
- Entry information
- Similar proteins
- BLAST>sp|P22949|MCRB_METTE Methyl-coenzyme M reductase subunit beta (Fragment) OS=Methanosarcina thermophila PE=1 SV=1 SDTVDIYDAGKILERVII
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- HistoryEntry version 45 (03 Sep 2014)
Sequence version 1 (01 Aug 1991)
Previous versions | rss
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Select a section on the left to see content.Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide.Methyl-CoM + CoB = CoM-S-S-CoB + methane.
<p>Describes biophysical and chemical properties, such as maximal absorption, kinetic parameters, pH dependence, redox potentials and temperature dependence.</p><p><a href='../manual/biophysicochemical_properties' target='_top'>More...</a></p>Temperature dependenceiOptimum temperature is 60 degrees Celsius.
<p>Describes the metabolic pathway(s) associated with a protein.</p><p><a href='../manual/pathway' target='_top'>More...</a></p>Pathwayi
- coenzyme-B sulfoethylthiotransferase activity Source: UniProtKB-EC
- methanogenesis Source: UniProtKB-KW
<div> <p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Biological processiMethanogenesis
Enzyme and pathway databases
UniPathway: a resource for the exploration and annotation of metabolic pathways<br/><a href='/database/170'>More..</a>UniPathwayi UPA00646; UER00699.Recommended name:Methyl-coenzyme M reductase subunit beta (EC:18.104.22.168)Alternative name(s):Coenzyme-B sulfoethylthiotransferase beta Methanosarcina thermophila 2210 [NCBI] cellular organisms › Archaea › Euryarchaeota › Methanomicrobia › Methanosarcinales › Methanosarcinaceae › Methanosarcina
Feature key Position(s) Length Description Graphical view Feature identifier Actions 1 – ›18 ›18 Methyl-coenzyme M reductase subunit beta PRO_0000147470 Add
BLASTHeterotrimer composed of an alpha, a beta, and a gamma subunit.
<p>Indicates if the canonical sequence displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.Length:18Mass (Da):2,020Last modified:August 1, 1991 - v1<div> <p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> </div> Checksum:i3783D55E2C6E369D
Feature key Position(s) Length Description Graphical view Feature identifier Actions <p>Is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.</p><p><a href='../manual/non_ter' target='_top'>More...</a></p>Non-terminal residuei 18 – 18 1
3D structure databases
Database of comparative protein structure models<br/><a href='/database/63'>More..</a> ModBasei Search... Search...
Protocols and materials databases
Structural Biology Knowledgebase Search...
Enzyme and pathway databases
UniPathway: a resource for the exploration and annotation of metabolic pathways<br/><a href='/database/170'>More..</a> UniPathwayi UPA00646 ; UER00699 .
Family and domain databases
Search... MCRB_METTE P22949Primary (citable) accession number: P22949 Integrated into UniProtKB/Swiss-Prot: August 1, 1991 Last sequence update: August 1, 1991 Last modified: September 3, 2014 This is version 45 of the entry and version 1 of the sequence. [Complete history] Reviewed (UniProtKB/Swiss-Prot) Annotation program Prokaryotic Protein Annotation Program
MiscellaneousReduced ferredoxin could reductively reactivate the enzyme.
- PATHWAY commentsIndex of metabolic and biosynthesis pathways
External DataDasty 3