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P22927

- CHSG_PETHY

UniProt

P22927 - CHSG_PETHY

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Protein
Chalcone synthase G
Gene
CHSG
Organism
Petunia hybrida (Petunia)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase G (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase G
Gene namesi
Name:CHSG
OrganismiPetunia hybrida (Petunia)
Taxonomic identifieri4102 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 393393Chalcone synthase G
PRO_0000216033Add
BLAST

Expressioni

Tissue specificityi

Expressed in seedlings after illumination with UV light. No expression detectable in flowers. It is not known for sure whether CHSG encodes a chalcone synthase or a very closely related condensing enzyme.

Structurei

3D structure databases

ProteinModelPortaliP22927.
SMRiP22927. Positions 3-392.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22927-1 [UniParc]FASTAAdd to Basket

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MATVEEIRKA QRAEGPATVL AIGTANPSNC VDQSAYPDFL FRITTSDHKT    50
ELKEKFKHMC EGSMIKKRYL HLTEEILKNN PNICEHKAPS LNARQEIAVA 100
EAPKLGKRAA QKAIEEWSQS KSKITHLVFC TTTSVELPGA DYQLTKLLGL 150
SPSVKRSMMY QQGCYGGGTA LRLAKDLAEN NKGARVLVVC VEITVMSFQA 200
PSRNDTDELD VLVGQALFAD GASAVIIGSD PILAIEKPLF ELVFATQTLI 250
PDSGHVICAN LTEAGLIPHL LKDAPIVISQ NIERRLVEVF KPLGISDWNS 300
IFWVAHPGGP AILNQIELKL GLKPEKLRAA RHVLSEYGNM SSACVLFVLD 350
EMRKGTIEKG MGTTGEGLEW GLLFGFGPGL TIETVVLHSV SIN 393
Length:393
Mass (Da):42,828
Last modified:April 1, 1993 - v2
Checksum:i575E56627EFC18D8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14595 Genomic DNA. Translation: CAA32735.1.
PIRiC72821. SYPJCG.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14595 Genomic DNA. Translation: CAA32735.1 .
PIRi C72821. SYPJCG.

3D structure databases

ProteinModelPortali P22927.
SMRi P22927. Positions 3-392.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and molecular characterization of the chalcone synthase multigene family of Petunia hybrida."
    Koes R.E., Spelt C.E., van den Elzen P.J.M., Mol J.N.M.
    Gene 81:245-257(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Violet 30.
    Tissue: Leaf.

Entry informationi

Entry nameiCHSG_PETHY
AccessioniPrimary (citable) accession number: P22927
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: April 1, 1993
Last modified: February 19, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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