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P22927

- CHSG_PETHY

UniProt

P22927 - CHSG_PETHY

Protein

Chalcone synthase G

Gene

CHSG

Organism
Petunia hybrida (Petunia)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 80 (01 Oct 2014)
      Sequence version 2 (01 Apr 1993)
      Previous versions | rss
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    • Comment

    Functioni

    The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

    Catalytic activityi

    3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei164 – 1641PROSITE-ProRule annotation

    GO - Molecular functioni

    1. naringenin-chalcone synthase activity Source: UniProtKB-EC

    GO - Biological processi

    1. flavonoid biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Acyltransferase, Transferase

    Keywords - Biological processi

    Flavonoid biosynthesis

    Enzyme and pathway databases

    UniPathwayiUPA00154.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Chalcone synthase G (EC:2.3.1.74)
    Alternative name(s):
    Naringenin-chalcone synthase G
    Gene namesi
    Name:CHSG
    OrganismiPetunia hybrida (Petunia)
    Taxonomic identifieri4102 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 393393Chalcone synthase GPRO_0000216033Add
    BLAST

    Expressioni

    Tissue specificityi

    Expressed in seedlings after illumination with UV light. No expression detectable in flowers. It is not known for sure whether CHSG encodes a chalcone synthase or a very closely related condensing enzyme.

    Structurei

    3D structure databases

    ProteinModelPortaliP22927.
    SMRiP22927. Positions 3-392.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the chalcone/stilbene synthases family.Curated

    Family and domain databases

    Gene3Di3.40.47.10. 2 hits.
    InterProiIPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view]
    PfamiPF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000451. PKS_III. 1 hit.
    SUPFAMiSSF53901. SSF53901. 2 hits.
    PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P22927-1 [UniParc]FASTAAdd to Basket

    « Hide

    MATVEEIRKA QRAEGPATVL AIGTANPSNC VDQSAYPDFL FRITTSDHKT    50
    ELKEKFKHMC EGSMIKKRYL HLTEEILKNN PNICEHKAPS LNARQEIAVA 100
    EAPKLGKRAA QKAIEEWSQS KSKITHLVFC TTTSVELPGA DYQLTKLLGL 150
    SPSVKRSMMY QQGCYGGGTA LRLAKDLAEN NKGARVLVVC VEITVMSFQA 200
    PSRNDTDELD VLVGQALFAD GASAVIIGSD PILAIEKPLF ELVFATQTLI 250
    PDSGHVICAN LTEAGLIPHL LKDAPIVISQ NIERRLVEVF KPLGISDWNS 300
    IFWVAHPGGP AILNQIELKL GLKPEKLRAA RHVLSEYGNM SSACVLFVLD 350
    EMRKGTIEKG MGTTGEGLEW GLLFGFGPGL TIETVVLHSV SIN 393
    Length:393
    Mass (Da):42,828
    Last modified:April 1, 1993 - v2
    Checksum:i575E56627EFC18D8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14595 Genomic DNA. Translation: CAA32735.1.
    PIRiC72821. SYPJCG.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X14595 Genomic DNA. Translation: CAA32735.1 .
    PIRi C72821. SYPJCG.

    3D structure databases

    ProteinModelPortali P22927.
    SMRi P22927. Positions 3-392.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00154 .

    Family and domain databases

    Gene3Di 3.40.47.10. 2 hits.
    InterProi IPR012328. Chalcone/stilbene_synth_C.
    IPR018088. Chalcone/stilbene_synthase_AS.
    IPR001099. Chalcone/stilbene_synthase_N.
    IPR011141. Polyketide_synthase_type-III.
    IPR016039. Thiolase-like.
    IPR016038. Thiolase-like_subgr.
    [Graphical view ]
    Pfami PF02797. Chal_sti_synt_C. 1 hit.
    PF00195. Chal_sti_synt_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000451. PKS_III. 1 hit.
    SUPFAMi SSF53901. SSF53901. 2 hits.
    PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning and molecular characterization of the chalcone synthase multigene family of Petunia hybrida."
      Koes R.E., Spelt C.E., van den Elzen P.J.M., Mol J.N.M.
      Gene 81:245-257(1989) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: cv. Violet 30.
      Tissue: Leaf.

    Entry informationi

    Entry nameiCHSG_PETHY
    AccessioniPrimary (citable) accession number: P22927
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 1, 1991
    Last sequence update: April 1, 1993
    Last modified: October 1, 2014
    This is version 80 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3