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P22926

- CHSF_PETHY

UniProt

P22926 - CHSF_PETHY

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Protein

Chalcone synthase F

Gene

CHSF

Organism
Petunia hybrida (Petunia)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.PROSITE-ProRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641PROSITE-ProRule annotation

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase F (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase F
Gene namesi
Name:CHSF
OrganismiPetunia hybrida (Petunia)
Taxonomic identifieri4102 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 389389Chalcone synthase FPRO_0000216032Add
BLAST

Expressioni

Tissue specificityi

CHSF does not appear to be pseudogene, but expression of this gene could not be detected in various floral tissues nor in seedlings after illumination with UV light.

Structurei

3D structure databases

ProteinModelPortaliP22926.
SMRiP22926. Positions 3-389.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the chalcone/stilbene synthases family.Curated

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22926-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MVSVEEVRRA QRREGPATIL AIGTATPLNC VDQTTYPDYF FRVTNSDHKT
60 70 80 90 100
ELKEKFKRMF ERSMIKKSYL HLTEEILKEN PSICEHKAPS FDARQDIVVV
110 120 130 140 150
EVPKLGKEAA QNAIKEWGQP KSKITHLVFC TTTGVDMHGA DYQLTKLLGL
160 170 180 190 200
SPSVKRLMMY QLGCYGGGTV LRLAKDLAEN NKGARALVVC SEITAITFHA
210 220 230 240 250
PSDTDLDVLV GQALFGDGAA SVIIGSDPNL EVEKPLFELV SAAQTLVPDC
260 270 280 290 300
GHKIYGKTSD VGLTFHLHKD VPRLVSQNIE KSLVEVFQPL GIFDWNSIFW
310 320 330 340 350
VGHAGGREIL DQVELKLGLK PEKLNVTRHV MSEYGNMASA CVLFVLDEMR
360 370 380
KTSTKEGFGT NVEGLEWGVL CSFGPGLTIE TIVLHSVSI
Length:389
Mass (Da):42,934
Last modified:April 1, 1993 - v2
Checksum:i35DA471B679FB7A0
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14594 Genomic DNA. Translation: CAA32734.1.
PIRiB72821. SYPJCF.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14594 Genomic DNA. Translation: CAA32734.1 .
PIRi B72821. SYPJCF.

3D structure databases

ProteinModelPortali P22926.
SMRi P22926. Positions 3-389.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and molecular characterization of the chalcone synthase multigene family of Petunia hybrida."
    Koes R.E., Spelt C.E., van den Elzen P.J.M., Mol J.N.M.
    Gene 81:245-257(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Violet 30.
    Tissue: Leaf.

Entry informationi

Entry nameiCHSF_PETHY
AccessioniPrimary (citable) accession number: P22926
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: April 1, 1993
Last modified: October 1, 2014
This is version 79 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3