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P22925

- CHSD_PETHY

UniProt

P22925 - CHSD_PETHY

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Protein
Chalcone synthase D
Gene
CHSD
Organism
Petunia hybrida (Petunia)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin.

Catalytic activityi

3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei164 – 1641 By similarity

GO - Molecular functioni

  1. naringenin-chalcone synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. flavonoid biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Keywords - Biological processi

Flavonoid biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00154.

Names & Taxonomyi

Protein namesi
Recommended name:
Chalcone synthase D (EC:2.3.1.74)
Alternative name(s):
Naringenin-chalcone synthase D
Gene namesi
Name:CHSD
OrganismiPetunia hybrida (Petunia)
Taxonomic identifieri4102 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsSolanalesSolanaceaePetunioideaePetunia

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 419419Chalcone synthase D
PRO_0000216031Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP22925.
SMRiP22925. Positions 3-388.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.47.10. 2 hits.
InterProiIPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view]
PfamiPF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000451. PKS_III. 1 hit.
SUPFAMiSSF53901. SSF53901. 2 hits.
PROSITEiPS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22925-1 [UniParc]FASTAAdd to Basket

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MVTVEEVRNA QRAEGPATVL AIGTATPSNC VDQSTYPDYY FRITDSEHKT    50
ELKEKFKRIC DKSMIKKRYM HLTEKILKEN PNICESMAPS LDARTNIYAV 100
EVPKLGKEAA EKAIEEWNQP KSRITHLVFC TTTGVSMPGA DFQLTKLLGL 150
GSSVKRFMMN QLGCFAGGTV LRLAKDLAEN NKGARVLVVC SEITVVTFRG 200
PNDTHFDSLV GQALFGDGAA AVIIGSDPIP NVERPLFELV SAAQTLLPDS 250
KNSICGELRE IGLTFHLLKD VAELISNNIE KSLVEVFQPL GISAWNSIFW 300
VAHPGGPAIL NQVELKLGLN PEKLGATRHV LSEYGNMSSA SILFVLDEMR 350
KSSTQKGFDT TGEGLKWGVL IGFGPGITFE TIVLHSVSTQ GSFGIRDWDY 400
NFGIEFKIIF IPYLVLGIS 419
Length:419
Mass (Da):45,979
Last modified:April 1, 1993 - v2
Checksum:i55827338DC812ACD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14593 Genomic DNA. Translation: CAA32733.1.
PIRiA72821. SYPJCD.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X14593 Genomic DNA. Translation: CAA32733.1 .
PIRi A72821. SYPJCD.

3D structure databases

ProteinModelPortali P22925.
SMRi P22925. Positions 3-388.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00154 .

Family and domain databases

Gene3Di 3.40.47.10. 2 hits.
InterProi IPR012328. Chalcone/stilbene_synth_C.
IPR018088. Chalcone/stilbene_synthase_AS.
IPR001099. Chalcone/stilbene_synthase_N.
IPR011141. Polyketide_synthase_type-III.
IPR016039. Thiolase-like.
IPR016038. Thiolase-like_subgr.
[Graphical view ]
Pfami PF02797. Chal_sti_synt_C. 1 hit.
PF00195. Chal_sti_synt_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000451. PKS_III. 1 hit.
SUPFAMi SSF53901. SSF53901. 2 hits.
PROSITEi PS00441. CHALCONE_SYNTH. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and molecular characterization of the chalcone synthase multigene family of Petunia hybrida."
    Koes R.E., Spelt C.E., van den Elzen P.J.M., Mol J.N.M.
    Gene 81:245-257(1989) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: cv. Violet 30.
    Tissue: Leaf.

Entry informationi

Entry nameiCHSD_PETHY
AccessioniPrimary (citable) accession number: P22925
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: April 1, 1993
Last modified: February 19, 2014
This is version 77 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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