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Protein

Transposase from transposon Tn916

Gene

Int-Tn

Organism
Enterococcus faecalis (Streptococcus faecalis)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei378O-(3'-phospho-DNA)-tyrosine intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processDNA integration, DNA recombination, Viral genome integration, Virus entry into host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Transposase from transposon Tn916
Alternative name(s):
Integrase
Gene namesi
Name:Int-Tn
OrganismiEnterococcus faecalis (Streptococcus faecalis)
Taxonomic identifieri1351 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesEnterococcaceaeEnterococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001975591 – 405Transposase from transposon Tn916Add BLAST405

Structurei

Secondary structure

1405
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi8 – 11Combined sources4
Beta strandi17 – 19Combined sources3
Beta strandi21 – 23Combined sources3
Beta strandi25 – 30Combined sources6
Beta strandi34 – 42Combined sources9
Helixi60 – 68Combined sources9

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1B69NMR-A3-71[»]
1BB8NMR-A3-73[»]
1TN9NMR-A3-71[»]
2BB8NMR-A3-73[»]
ProteinModelPortaliP22886.
SMRiP22886.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP22886.

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family.Curated

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
InterProiView protein in InterPro
IPR016177. DNA-bd_dom_sf.
IPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat_sf.
IPR002104. Integrase_catalytic.
IPR010998. Integrase_recombinase_N.
IPR004191. Integrase_Tn916-type_DNA-bd_N.
IPR025269. SAM-like_dom.
PfamiView protein in Pfam
PF02920. Integrase_DNA. 1 hit.
PF13102. Phage_int_SAM_5. 1 hit.
PF00589. Phage_integrase. 1 hit.
SUPFAMiSSF54171. SSF54171. 1 hit.
SSF56349. SSF56349. 1 hit.

Sequencei

Sequence statusi: Complete.

P22886-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKRRDNRG RILKTGESQR KDGRYLYKYI DSFGEPQFVY SWKLVATDRV
60 70 80 90 100
PAGKRDCISL REKIAELQKD IHDGIDVVGK KMTLCQLYAK QNAQRPKVRK
110 120 130 140 150
NTETGRKYLM DILKKDKLGV RSIDSIKPSD AKEWAIRMSE NGYAYQTINN
160 170 180 190 200
YKRSLKASFY IAIQDDCVRK NPFDFQLKAV LDDDTVPKTV LTEEQEEKLL
210 220 230 240 250
AFAKADKTYS KNYDEILILL KTGLRISEFG GLTLPDLDFE NRLVNIDHQL
260 270 280 290 300
LRDTEIGYYI ETPKTKSGER QVPMVEEAYQ AFKRVLANRK NDKRVEIDGY
310 320 330 340 350
SDFLFLNRKN YPKVASDYNG MMKGLVKKYN KYNEDKLPHI TPHSLRHTFC
360 370 380 390 400
TNYANAGMNP KALQYIMGHA NIAMTLNYYA HATFDSAMAE MKRLNKEKQQ

ERLVA
Length:405
Mass (Da):47,050
Last modified:August 1, 1991 - v1
Checksum:i33E7AF825154E619
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37184 Genomic DNA. Translation: AAA19427.1.
U09422 Genomic DNA. Translation: AAB60030.1.

Similar proteinsi

Entry informationi

Entry nameiTNR6_ENTFL
AccessioniPrimary (citable) accession number: P22886
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: November 22, 2017
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Transposable element

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families