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P22772

- MTB3_ANEAE

UniProt

P22772 - MTB3_ANEAE

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Protein
Modification methylase BanIII
Gene
banIIIM
Organism
Aneurinibacillus aneurinilyticus (Bacillus aneurinolyticus)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

This methylase recognizes the double-stranded sequence ATCGAT, causes specific methylation on A-5 on both strands, and protects the DNA from cleavage by the BanIII endonuclease.

Catalytic activityi

S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. N-methyltransferase activity Source: InterPro
  3. site-specific DNA-methyltransferase (adenine-specific) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA restriction-modification system Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

Restriction system

Keywords - Ligandi

S-adenosyl-L-methionine

Protein family/group databases

REBASEi3296. M.BanIII.

Names & Taxonomyi

Protein namesi
Recommended name:
Modification methylase BanIII (EC:2.1.1.72)
Short name:
M.BanIII
Alternative name(s):
Adenine-specific methyltransferase BanIII
Gene namesi
Name:banIIIM
OrganismiAneurinibacillus aneurinilyticus (Bacillus aneurinolyticus)
Taxonomic identifieri1391 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPaenibacillaceaeAneurinibacillus groupAneurinibacillus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 580580Modification methylase BanIII
PRO_0000087943Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP22772.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
InterProiIPR003356. DNA_methylase_A-5.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR002296. N12N6_MeTrfase.
IPR029063. SAM-dependent_MTases-like.
IPR025931. TaqI_C.
[Graphical view]
PfamiPF02384. N6_Mtase. 1 hit.
PF12950. TaqI_C. 1 hit.
[Graphical view]
PRINTSiPR00507. N12N6MTFRASE.
SUPFAMiSSF53335. SSF53335. 1 hit.
PROSITEiPS00092. N6_MTASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22772-1 [UniParc]FASTAAdd to Basket

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MELTIEEMLI KQKETGAHYT PTDLGDIIAK RLINELKKSG ISGTKKIRGL    50
DPSCGDGELL LSLNRIAKFN NIDNIELIGI DEDKEAIKEA DFRLNEMGIN 100
DAKLTAGDFL DMVDLEGNLS LFDDDLSKIE PVDLIIANPP YVRTQVLGAD 150
RAQKLAKLFN LKGRVDLYHA FLVAMTLQLK PGGLIGVITS NKYLANSSGE 200
SIRQFLAENY DIIEIMDLGD TKLFSAAVLQ AIFFGRKKVN KGIRQTAPAN 250
FYKIYEETDP SKTEVSIKFE TLFGLLESSN TGVFNVDEKF YSVSCGKLIV 300
PDSFKEPWVM ATDEEYNWIT NINNNSYCTI QDLCDVKVGI KTTADKVFIK 350
STWEELPDEI KPEVEVLKLL ISTDHASKWR PLERIPNQKI LYTHENVNGK 400
KKAIDFTQYP HALAYLETHR ETLEGRKYVI KAKRNWYEIW VPQNPDHWAL 450
PKIVFPDISP EPKFFYEDEG CCIDGNCYWI IPKEENNNDI LFLILGISNT 500
KYMTNYHDIA FNNKLYPGRR RYLTQYVSKY PLPNPEANYS QEIIDLVREL 550
VFQNPNDERK IEIENQIENL TALAFGVERL 580
Length:580
Mass (Da):66,345
Last modified:August 1, 1991 - v1
Checksum:i0E4DF7357EC394C7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83417 Genomic DNA. Translation: CAA58443.1. Sequence problems.
PIRiJH0224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
X83417 Genomic DNA. Translation: CAA58443.1 . Sequence problems.
PIRi JH0224.

3D structure databases

ProteinModelPortali P22772.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

REBASEi 3296. M.BanIII.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.150. 1 hit.
InterProi IPR003356. DNA_methylase_A-5.
IPR002052. DNA_methylase_N6_adenine_CS.
IPR002296. N12N6_MeTrfase.
IPR029063. SAM-dependent_MTases-like.
IPR025931. TaqI_C.
[Graphical view ]
Pfami PF02384. N6_Mtase. 1 hit.
PF12950. TaqI_C. 1 hit.
[Graphical view ]
PRINTSi PR00507. N12N6MTFRASE.
SUPFAMi SSF53335. SSF53335. 1 hit.
PROSITEi PS00092. N6_MTASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence of the gene coding for the BanIII DNA methyltransferase in Bacillus aneurinolyticus."
    Kawakami B., Sasaki A., Oka M., Maekawa Y.
    Agric. Biol. Chem. 54:3227-3233(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiMTB3_ANEAE
AccessioniPrimary (citable) accession number: P22772
Secondary accession number(s): Q44656
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: June 11, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Restriction enzymes and methylases
    Classification of restriction enzymes and methylases and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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