##gff-version 3
P22694	UniProtKB	Initiator methionine	1	1	.	.	.	Note=Removed;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25255805;Dbxref=PMID:25255805	
P22694	UniProtKB	Chain	2	351	.	.	.	ID=PRO_0000086060;Note=CAMP-dependent protein kinase catalytic subunit beta	
P22694	UniProtKB	Domain	44	298	.	.	.	Note=Protein kinase;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P22694	UniProtKB	Domain	299	351	.	.	.	Note=AGC-kinase C-terminal;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00618	
P22694	UniProtKB	Active site	167	167	.	.	.	Note=Proton acceptor;Ontology_term=ECO:0000255,ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159,ECO:0000255|PROSITE-ProRule:PRU10027	
P22694	UniProtKB	Binding site	50	58	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P22694	UniProtKB	Binding site	73	73	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00159	
P22694	UniProtKB	Modified residue	3	3	.	.	.	Note=Deamidated asparagine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05383	
P22694	UniProtKB	Modified residue	11	11	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05132	
P22694	UniProtKB	Modified residue	69	69	.	.	.	Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P68181	
P22694	UniProtKB	Modified residue	140	140	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05132	
P22694	UniProtKB	Modified residue	198	198	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05132	
P22694	UniProtKB	Modified residue	322	322	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P68182	
P22694	UniProtKB	Modified residue	331	331	.	.	.	Note=Phosphotyrosine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P05132	
P22694	UniProtKB	Modified residue	339	339	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P68182	
P22694	UniProtKB	Lipidation	2	2	.	.	.	Note=N-myristoyl glycine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:25255805;Dbxref=PMID:25255805	
P22694	UniProtKB	Alternative sequence	1	16	.	.	.	ID=VSP_017364;Note=In isoform 2. MGNAATAKKGSEVESV->MAAYREPPCNQYTGTTTALQKLEGFASRLFHRHSKGTAHDQKTALENDSLHFSEHTALWDRSM;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11589697,ECO:0000303|PubMed:17974005;Dbxref=PMID:11589697,PMID:17974005	
P22694	UniProtKB	Alternative sequence	1	15	.	.	.	ID=VSP_017365;Note=In isoform 6. MGNAATAKKGSEVES->MSARKSSDASACSSSEISDSF;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11589697,ECO:0000303|Ref.3;Dbxref=PMID:11589697	
P22694	UniProtKB	Alternative sequence	1	15	.	.	.	ID=VSP_043372;Note=In isoform 9. MGNAATAKKGSEVES->MGLSRKSSDASACSSSEISDSF;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
P22694	UniProtKB	Alternative sequence	1	14	.	.	.	ID=VSP_017366;Note=In isoform 5 and isoform 10. MGNAATAKKGSEVE->MSARKSSDASACSSSEI;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11589697,ECO:0000303|PubMed:14702039;Dbxref=PMID:11589697,PMID:14702039	
P22694	UniProtKB	Alternative sequence	1	14	.	.	.	ID=VSP_017367;Note=In isoform 7. MGNAATAKKGSEVE->MGLSRKSSDASACSSSEI;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:17974005;Dbxref=PMID:17974005	
P22694	UniProtKB	Alternative sequence	1	13	.	.	.	ID=VSP_017368;Note=In isoform 4. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:11589697;Dbxref=PMID:11589697	
P22694	UniProtKB	Alternative sequence	1	12	.	.	.	ID=VSP_017369;Note=In isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11589697,ECO:0000303|PubMed:14702039;Dbxref=PMID:11589697,PMID:14702039	
P22694	UniProtKB	Alternative sequence	13	16	.	.	.	ID=VSP_017370;Note=In isoform 3. VESV->MGLL;Ontology_term=ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:11589697,ECO:0000303|PubMed:14702039;Dbxref=PMID:11589697,PMID:14702039	
P22694	UniProtKB	Alternative sequence	14	14	.	.	.	ID=VSP_017371;Note=In isoform 4. E->M;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:11589697;Dbxref=PMID:11589697	
P22694	UniProtKB	Alternative sequence	79	111	.	.	.	ID=VSP_046238;Note=In isoform 10. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
P22694	UniProtKB	Alternative sequence	256	257	.	.	.	ID=VSP_036556;Note=In isoform 8. VR->NF;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
P22694	UniProtKB	Alternative sequence	258	351	.	.	.	ID=VSP_036557;Note=In isoform 8. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:15489334;Dbxref=PMID:15489334	
P22694	UniProtKB	Natural variant	54	54	.	.	.	ID=VAR_085199;Note=In CAFD2. S->L;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33058759;Dbxref=dbSNP:rs1663748771,PMID:33058759	
P22694	UniProtKB	Natural variant	88	88	.	.	.	ID=VAR_085200;Note=In CAFD2. H->N;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33058759;Dbxref=PMID:33058759	
P22694	UniProtKB	Natural variant	88	88	.	.	.	ID=VAR_085201;Note=In CAFD2%3B increased sensitivity to cAMP activation. H->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33058759;Dbxref=dbSNP:rs768056300,PMID:33058759	
P22694	UniProtKB	Natural variant	106	106	.	.	.	ID=VAR_040594;Note=R->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:17344846;Dbxref=dbSNP:rs36117118,PMID:17344846	
P22694	UniProtKB	Natural variant	235	235	.	.	.	ID=VAR_085202;Note=In CAFD2%3B increased sensitivity to cAMP activation%3B decreased interaction with regulatory subunits PRKAR1A and PRKAR2B. G->R;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:33058759;Dbxref=dbSNP:rs1670492319,PMID:33058759	
P22694	UniProtKB	Sequence conflict	80	80	.	.	.	Note=V->G;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P22694	UniProtKB	Sequence conflict	159	159	.	.	.	Note=H->N;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P22694	UniProtKB	Sequence conflict	163	163	.	.	.	Note=L->I;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P22694	UniProtKB	Sequence conflict	233	233	.	.	.	Note=A->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P22694	UniProtKB	Sequence conflict	261	261	.	.	.	Note=H->N;Ontology_term=ECO:0000305;evidence=ECO:0000305