ID   CBL$HUMAN      STANDARD;      PRT;   906 AA.
AC   P22681;
DT   01-AUG-1991 (REL. 19, CREATED)
DT   01-AUG-1991 (REL. 19, LAST SEQUENCE UPDATE)
DT   01-NOV-1991 (REL. 20, LAST ANNOTATION UPDATE)
DE   PROTO-ONCOGENE C-CBL (GENE NAME: C-CBL).
OS   HOMO SAPIENS (HUMAN).
OC   EUKARYOTA; METAZOA; CHORDATA; VERTEBRATA; TETRAPODA; MAMMALIA;
OC   EUTHERIA; PRIMATES.
RN   [1]
RP   SEQUENCE FROM N.A.
RC   MEDLINE=91232862;
RA   BLAKE T.J., SHAPIRO M., MORSE H.C. III, LANGDON W.Y.;
RL   ONCOGENE 6:653-657(1991).
CC   -!- SUBCELLULAR LOCATION: NUCLEAR.
CC   -!- SIMILARITY: CONTAINS A C3HC4-CLASS ZINC FINGER.
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DR   EMBL; X57110; HSCCBL.
DR   PROSITE; PS00518; ZINC_FINGER_C3HC4.
KW   PROTO-ONCOGENE; NUCLEAR PROTEIN; ZINC-FINGER; DNA-BINDING.
FT   DOMAIN      124    127       NUCLEAR LOCALIZATION SIGNAL
FT                                (POTENTIAL).
FT   ZN_FING     381    419       ZINC FINGER, C3HC4-TYPE.
FT   DOMAIN      357    476       ACIDIC.
FT   DOMAIN      477    688       PROLINE-RICH.
FT   DOMAIN      689    834       ACIDIC.
FT   DOMAIN      857    892       LEUCINE-ZIPPER.
SQ   SEQUENCE   906 AA;  99646 MW;  4258679 CN;
     MAGNVKKSSG AGGGTGSGGS GSGGLIGLMK DAFQPHHHHH HHLSPHPPGT VDKKMVEKCW
     KLMDKVVRLC QNPKLALKNS PPYILDLLPD TYQHLRTILS RYEGKMETLG ENEYFRVFME
     NLMKKTKQTI SLFKEGKERM YEENSQPRRN LTKLSLIFSH MLAELKGIFP SGLFQGDTFR
     ITKADAAEFW RKAFGEKTIV PWKSFRQALH EVHPISSGLE AMALKSTIDL TCNDYISVFE
     FDIFTRLFQP WSSLLRNWNS LAVTHPGYMA FLTYDEVKAR LQKFIHKPGS YIFRLSCTRL
     GQWAIGYVTA DGNILQTIPH NKPLFQALID GFREGFYLFP DGRNQNPDLT GLCEPTPQDH
     IKVTQEQYEL YCEMGSTFQL CKICAENDKD VKIEPCGHLM CTSCLTSWQE SEGQGCPFCR
     CEIKGTEPIV VDPFDPRGSG SLLRQGAEGA PSPNYDDDDD ERADDTLFMM KELAGAKVER
     PPSPFSMAPQ ASLPPVPPRL DLLPQRVCVP SSASALGTAS KAASGSLHKD KPLPVPPTLR
     DLPPPPPPDR PYSVGAESRP QRRPLPCTPG DCPSRDKLPP VPSSRLGDSW LPRPIPKVPV
     SAPSSSDPWT GRELTNRHSL PFSLPSQMEP RPDVPRLGST FSLDTSMSMN SSPLVGPECD
     HPKIKPSSSA NAIYSLAARP LPVPKLPPGE QCEGEEDTEY MTPSSRPLRP LDTSQSSRAC
     DCDQQIDSCT YEAMYNIQSQ APSITESSTF GEGNLAAAHA NTGPEESENE DDGYDVPKPP
     VPAVLARRTL SDISNASSSF GWLSLDGDPT TNVTEGSQVP ERPPKPFPRR INSERKAGSC
     QQGSGPAASA ATASPQLSSE IENLMSQGYS YQDIQKALVI AQNNIEMAKN ILREFVSISS
     PAHVAT
//