Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P22669

- GUN_ASPAC

UniProt

P22669 - GUN_ASPAC

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Endoglucanase-1

Gene
N/A
Organism
Aspergillus aculeatus
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

GO - Molecular functioni

  1. cellulase activity Source: UniProtKB-EC

GO - Biological processi

  1. cellulose catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Protein family/group databases

CAZyiGH12. Glycoside Hydrolase Family 12.

Names & Taxonomyi

Protein namesi
Recommended name:
Endoglucanase-1 (EC:3.2.1.4)
Alternative name(s):
Cellulase
Endo-1,4-beta-glucanase
Endoglucanase I
FI-CMCase
OrganismiAspergillus aculeatus
Taxonomic identifieri5053 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Subcellular locationi

GO - Cellular componenti

  1. extracellular region Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence AnalysisAdd
BLAST
Chaini17 – 237221Endoglucanase-1PRO_0000008018Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei17 – 171Pyrrolidone carboxylic acid1 Publication

Keywords - PTMi

Pyrrolidone carboxylic acid

Expressioni

Inductioni

By cellulosic materials and hemicelluloses.

Structurei

3D structure databases

ProteinModelPortaliP22669.
SMRiP22669. Positions 21-236.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.180. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR013319. Glyco_hydro_11/12.
IPR002594. Glyco_hydro_12.
[Graphical view]
PfamiPF01670. Glyco_hydro_12. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P22669-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKAFHLLAAL AGAAVAQQAQ LCDQYATYTG GVYTINNNLW GKDAGSGSQC
60 70 80 90 100
TTVNSASSAG TSWSTKWNWS GGENSVKSYA NSGLTFNKKL VSQISQIPTT
110 120 130 140 150
ARWSYDNTGI RADVAYDLFT AADINHVTWS GDYELMIWLA RYGGVQPIGS
160 170 180 190 200
QIATATVDGQ TWELWYGANG SQKTYSFVAP TPITSFQGDV NDFFKYLTQN
210 220 230
HGFPASSQYL ITLQFGTEPF TGGPATLSVS NWSASVQ
Length:237
Mass (Da):25,560
Last modified:August 1, 1991 - v1
Checksum:i8F173571A8AE6931
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00546 Genomic DNA. Translation: BAA00435.1.
X52525 mRNA. Translation: CAA36757.1.
PIRiS12610.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D00546 Genomic DNA. Translation: BAA00435.1 .
X52525 mRNA. Translation: CAA36757.1 .
PIRi S12610.

3D structure databases

ProteinModelPortali P22669.
SMRi P22669. Positions 21-236.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi GH12. Glycoside Hydrolase Family 12.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 2.60.120.180. 1 hit.
InterProi IPR013320. ConA-like_dom.
IPR013319. Glyco_hydro_11/12.
IPR002594. Glyco_hydro_12.
[Graphical view ]
Pfami PF01670. Glyco_hydro_12. 1 hit.
[Graphical view ]
SUPFAMi SSF49899. SSF49899. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Complete nucleotide sequence of a gene coding for Aspergillus aculeatus cellulase (FI-CMCase)."
    Ooi T., Shinmyo A., Okada H., Murao S., Kawaguchi T., Arai M.
    Nucleic Acids Res. 18:5884-5884(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: F-50.
  2. "Cloning and sequence analysis of a cDNA for cellulase (FI-CMCase) from Aspergillus aculeatus."
    Ooi T., Shinmyo A., Okada H., Hara S., Ikenaka T., Murao S., Arai M.
    Curr. Genet. 18:217-222(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
    Strain: F-50.

Entry informationi

Entry nameiGUN_ASPAC
AccessioniPrimary (citable) accession number: P22669
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 29, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Will also hydrolyze 1,4-linkages in beta-D-glucans also containing 1,3-linkages.

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3