P22659 (HOXU_RHOOP) Reviewed, UniProtKB/Swiss-Prot
Last modified
June 28, 2011.
Version 73.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: NAD-reducing hydrogenase hoxS subunit gamma EC=1.12.1.2 | ||
| Gene names |
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| Encoded on | Plasmid | ||
| Organism | Rhodococcus opacus (Nocardia opaca) | ||
| Taxonomic identifier | 37919 [NCBI] | ||
| Taxonomic lineage | Bacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Nocardiaceae › Rhodococcus |
Protein attributes
| Sequence length | 33 AA. |
| Sequence status | Fragment. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Subunits alpha and gamma of hoxS constitute an NADH--oxidoreductase. |
| Catalytic activity | H2 + NAD+ = H+ + NADH. |
| Cofactor | Binds 3 4Fe-4S clusters per subunit Potential. |
| Subunit structure | Tetramer of an alpha and a gamma subunits (flavin-containing dimer), and a delta and a nickel-containing beta subunits (hydrogenase dimer). |
| Subcellular location | |
| Sequence similarities | Belongs to the complex I 75 kDa subunit family. Contains 1 2Fe-2S ferredoxin-type domain. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cytoplasm |
| Ligand | 2Fe-2S 4Fe-4S FMN Flavoprotein Iron Iron-sulfur Metal-binding NAD |
| Molecular function | Oxidoreductase |
| Technical term | Direct protein sequencing Plasmid |
| Gene Ontology (GO) | |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | 2 iron, 2 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW 4 iron, 4 sulfur cluster bindingInferred from electronic annotation. Source: UniProtKB-KW hydrogen dehydrogenase activityInferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
Sequences
References
| [1] | "Comparison of the NH2-terminal amino acid sequences of the four non-identical subunits of the NAD-linked hydrogenases from Nocardia opaca 1b and Alcaligenes eutrophus H16." Zaborosch C., Schneider K., Schlegel H.G., Kratzin H. Eur. J. Biochem. 181:175-180(1989) [PubMed: 2496982] [Abstract] Cited for: PROTEIN SEQUENCE. Strain: 1B. |
Cross-references
3D structure databases | |
|---|---|
| ProteinModelPortal | P22659. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Family and domain databases | |
| InterPro | IPR012675. Beta-grasp_ferredoxin-type. [Graphical view] |
| Gene3D | G3DSA:3.10.20.30. Ferredoxin_fold. 1 hit. |
| PROSITE | PS00197. 2FE2S_FER_1. Partial match. PS51085. 2FE2S_FER_2. Partial match. PS00641. COMPLEX1_75K_1. Partial match. PS00642. COMPLEX1_75K_2. Partial match. PS00643. COMPLEX1_75K_3. Partial match. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | HOXU_RHOOP | ||||||||
| Accession | Primary (citable) accession number: P22659 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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