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P22636

- PCYB_SPHPI

UniProt

P22636 - PCYB_SPHPI

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Protein

Protocatechuate 4,5-dioxygenase beta chain

Gene

ligB

Organism
Sphingomonas paucimobilis (Pseudomonas paucimobilis)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Responsible for the aromatic ring fission of protocatechuate.

Catalytic activityi

Protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.

Cofactori

Fe2+ ion.

GO - Molecular functioni

  1. ferrous iron binding Source: InterPro
  2. protocatechuate 4,5-dioxygenase activity Source: UniProtKB-EC

GO - Biological processi

  1. aromatic compound catabolic process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Dioxygenase, Oxidoreductase

Keywords - Biological processi

Aromatic hydrocarbons catabolism

Keywords - Ligandi

Iron

Enzyme and pathway databases

BioCyciMetaCyc:MONOMER-15117.

Names & Taxonomyi

Protein namesi
Recommended name:
Protocatechuate 4,5-dioxygenase beta chain (EC:1.13.11.8)
Alternative name(s):
4,5-PCD
Gene namesi
Name:ligB
OrganismiSphingomonas paucimobilis (Pseudomonas paucimobilis)
Taxonomic identifieri13689 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaSphingomonadalesSphingomonadaceaeSphingomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 302302Protocatechuate 4,5-dioxygenase beta chainPRO_0000085101Add
BLAST

Interactioni

Subunit structurei

Composed of two subunits (alpha and beta) in a 1:1 ratio.

Protein-protein interaction databases

IntActiP22636. 1 interaction.

Structurei

Secondary structure

1
302
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi3 – 108
Helixi14 – 218
Turni28 – 303
Helixi31 – 4414
Turni47 – 493
Beta strandi52 – 587
Beta strandi62 – 643
Beta strandi69 – 768
Beta strandi78 – 814
Beta strandi87 – 904
Helixi100 – 11213
Beta strandi118 – 1225
Helixi127 – 13711
Beta strandi144 – 1529
Beta strandi155 – 1573
Helixi162 – 17716
Beta strandi179 – 1813
Beta strandi184 – 1907
Turni200 – 2034
Helixi207 – 21913
Helixi221 – 2244
Helixi229 – 2368
Helixi240 – 2434
Helixi244 – 2518
Beta strandi257 – 26812
Beta strandi271 – 28010
Helixi281 – 2833
Beta strandi289 – 2968

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1B4UX-ray2.20B/D1-302[»]
1BOUX-ray2.20B/D1-302[»]
ProteinModelPortaliP22636.
SMRiP22636. Positions 2-299.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP22636.

Family & Domainsi

Family and domain databases

Gene3Di3.40.830.10. 1 hit.
InterProiIPR004183. Xdiol_dOase_suB.
[Graphical view]
PfamiPF02900. LigB. 1 hit.
[Graphical view]
SUPFAMiSSF53213. SSF53213. 1 hit.

Sequencei

Sequence statusi: Complete.

P22636-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MARVTTGITS SHIPALGAAI QTGTSDNDYW GPVFKGYQPI RDWIKQPGNM
60 70 80 90 100
PDVVILVYND HASAFDMNII PTFAIGCAET FKPADEGWGP RPVPDVKGHP
110 120 130 140 150
DLAWHIAQSL ILDEFDMTIM NQMDVDHGCT VPLSMIFGEP EEWPCKVIPF
160 170 180 190 200
PVNVVTYPPP SGKRCFALGD SIRAAVESFP EDLNVHVWGT GGMSHQLQGP
210 220 230 240 250
RAGLINKEFD LNFIDKLISD PEELSKMPHI QYLRESGSEG VELVMWLIMR
260 270 280 290 300
GALPEKVRDL YTFYHIPASN TALGAMILQP EETAGTPLEP RKVMSGHSLA

QA
Length:302
Mass (Da):33,292
Last modified:August 1, 1991 - v1
Checksum:i0552B3B0E59702E5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M34835 Unassigned DNA. Translation: AAA17728.1.
PIRiB35271.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M34835 Unassigned DNA. Translation: AAA17728.1 .
PIRi B35271.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
1B4U X-ray 2.20 B/D 1-302 [» ]
1BOU X-ray 2.20 B/D 1-302 [» ]
ProteinModelPortali P22636.
SMRi P22636. Positions 2-299.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi P22636. 1 interaction.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

BioCyci MetaCyc:MONOMER-15117.

Miscellaneous databases

EvolutionaryTracei P22636.

Family and domain databases

Gene3Di 3.40.830.10. 1 hit.
InterProi IPR004183. Xdiol_dOase_suB.
[Graphical view ]
Pfami PF02900. LigB. 1 hit.
[Graphical view ]
SUPFAMi SSF53213. SSF53213. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Molecular cloning of the protocatechuate 4,5-dioxygenase genes of Pseudomonas paucimobilis."
    Noda Y., Nishikawa S., Shiozuka K., Kadokura H., Nakajima H., Yoda K., Katayama Y., Morohoshi N., Haraguchi T., Yamasaki M.
    J. Bacteriol. 172:2704-2709(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 1-9.
    Strain: SYK-6.

Entry informationi

Entry nameiPCYB_SPHPI
AccessioniPrimary (citable) accession number: P22636
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: December 11, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references

External Data

Dasty 3