P22614 (SAA3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Putative serum amyloid A-3 protein

Gene names

Name:	SAA3P
Synonyms:	SAA3

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	122 AA.
Sequence status	Complete.
Protein existence	Uncertain

General annotation (Comments)

Sequence similarities	Belongs to the SAA family.
Caution	Could be the product of a pseudogene.
Sequence caution	The sequence CAA32096.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	acute-phase response Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Non-traceable author statement. Source: UniProtKB
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 122	122	Putative serum amyloid A-3 protein		PRO_0000159088
Experimental info
	Sequence conflict	5	1	T → Y Ref.2
	Sequence conflict	32	1	A → T Ref.2
	Sequence conflict	37	1	R → K Ref.2
	Sequence conflict	49	1	K → N Ref.2
	Sequence conflict	57	1	R → W Ref.2
	Sequence conflict	67 – 69	3	PGG → LGA Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P22614 [UniParc]. Last modified August 1, 1991. Version 1. Checksum: 70F0BCC052E08472	FASTA	122	13,440
	10 20 30 40 50 60 MKLSTGIIFC SLVLGVSSQG WLTFLKAAGQ GAKDMWRAYS DMKEANYKKS DKYFHARGNY 70 80 90 100 110 120 DAVQRGPGGV WATEVISDAR ENVQRLTGDH AEDSLAGQAT NKWGQSGKDP NHFRPAGLPE KY

References

[1]	"The human serum amyloid A (SAA)-encoding gene GSAA1: nucleotide sequence and possible autocrine-collagenase-inducer function." Sack G.H. Jr., Talbot C.C. Jr. Gene 84:509-515(1989) [PubMed: 2558975] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]	"Nonexpression of the human serum amyloid A three (SAA3) gene." Kluve-Beckerman B., Drumm M.L., Benson M.D. DNA Cell Biol. 10:651-661(1991) [PubMed: 1755958] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	X13895 Genomic DNA. Translation: CAA32096.1. Different initiation. S73444 Genomic DNA. No translation available.
IPI	IPI00027191.
PIR	JN0029.
UniGene	Hs.454496.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	P22614.
Polymorphism databases
DMDM	134154.
Proteomic databases
PRIDE	P22614.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000278207; ENSP00000278207; ENSG00000166787.
Organism-specific databases
GeneCards	GC11M018090.
HGNC	HGNC:10515. SAA3P.
neXtProt	NX_P22614.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG20228.
GeneTree	ENSGT00390000004737.
HOGENOM	HBG261240.
HOVERGEN	HBG016327.
InParanoid	P22614.
OrthoDB	EOG4J119J.
Gene expression databases
ArrayExpress	P22614.
Genevestigator	P22614.
GermOnline	ENSG00000166787. Homo sapiens.
Family and domain databases
InterPro	IPR000096. Serum_amyloid_A. [Graphical view]
PANTHER	PTHR23424. Serum_amyloid_A. 1 hit.
Pfam	PF00277. SAA. 1 hit. [Graphical view]
PIRSF	PIRSF002472. Serum_amyloid_A. 1 hit.
PRINTS	PR00306. SERUMAMYLOID.
SMART	SM00197. SAA. 1 hit. [Graphical view]
PROSITE	PS00992. SAA. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SAA3_HUMAN

Accession

Primary (citable) accession number: P22614
Secondary accession number(s): O95735

Entry history

Integrated into UniProtKB/Swiss-Prot:	August 1, 1991
Last sequence update:	August 1, 1991
Last modified:	January 25, 2012
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.