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Protein

Flagellar protein FliO

Gene

fliO

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Chemotaxis, Flagellar rotation

Enzyme and pathway databases

BioCyciEcoCyc:EG11224-MONOMER.
ECOL316407:JW5316-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Flagellar protein FliO
Gene namesi
Name:fliO
Synonyms:flaP, flbD
Ordered Locus Names:b1947, JW5316
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG11224. fliO.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei19 – 39HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Bacterial flagellum, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002068431 – 121Flagellar protein FliOAdd BLAST121

Proteomic databases

PaxDbiP22586.
PRIDEiP22586.

Interactioni

Protein-protein interaction databases

BioGridi4261043. 14 interactors.
IntActiP22586. 1 interactor.
STRINGi511145.b1947.

Structurei

3D structure databases

ProteinModelPortaliP22586.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the FliO/MopB family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105K0P. Bacteria.
COG3190. LUCA.
HOGENOMiHOG000253556.
KOiK02418.
OMAiKRMQVPA.

Family and domain databases

InterProiIPR022781. Flagellar_biosynth_FliO.
[Graphical view]
PfamiPF04347. FliO. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03500. FliO_TIGR. 1 hit.

Sequencei

Sequence statusi: Complete.

P22586-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNNHATVQSS APVSAAPLLQ VSGALIAIIA LILAAAWLVK RLGFAPKRTG
60 70 80 90 100
VNGLKISASA SLGARERVVV VDVEDARLVL GVTAGQINLL HKLPPSAPTE
110 120
EIPQTDFQSV MKNLLKRSGR S
Length:121
Mass (Da):12,670
Last modified:April 27, 2001 - v3
Checksum:i0D4B6598368E60F5
GO

Sequence cautioni

The sequence AAC36858 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti15A → R in AAC36858 (PubMed:8282695).Curated1
Sequence conflicti18L → V in AAC36858 (PubMed:8282695).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22182 Genomic DNA. Translation: AAC36858.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75014.2.
AP009048 Genomic DNA. Translation: BAA15772.2.
RefSeqiNP_416457.4. NC_000913.3.
WP_001302429.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC75014; AAC75014; b1947.
BAA15772; BAA15772; BAA15772.
GeneIDi946458.
KEGGiecj:JW5316.
eco:b1947.
PATRICi32119223. VBIEscCol129921_2026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22182 Genomic DNA. Translation: AAC36858.1. Different initiation.
U00096 Genomic DNA. Translation: AAC75014.2.
AP009048 Genomic DNA. Translation: BAA15772.2.
RefSeqiNP_416457.4. NC_000913.3.
WP_001302429.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP22586.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4261043. 14 interactors.
IntActiP22586. 1 interactor.
STRINGi511145.b1947.

Proteomic databases

PaxDbiP22586.
PRIDEiP22586.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC75014; AAC75014; b1947.
BAA15772; BAA15772; BAA15772.
GeneIDi946458.
KEGGiecj:JW5316.
eco:b1947.
PATRICi32119223. VBIEscCol129921_2026.

Organism-specific databases

EchoBASEiEB1206.
EcoGeneiEG11224. fliO.

Phylogenomic databases

eggNOGiENOG4105K0P. Bacteria.
COG3190. LUCA.
HOGENOMiHOG000253556.
KOiK02418.
OMAiKRMQVPA.

Enzyme and pathway databases

BioCyciEcoCyc:EG11224-MONOMER.
ECOL316407:JW5316-MONOMER.

Miscellaneous databases

PROiP22586.

Family and domain databases

InterProiIPR022781. Flagellar_biosynth_FliO.
[Graphical view]
PfamiPF04347. FliO. 1 hit.
[Graphical view]
TIGRFAMsiTIGR03500. FliO_TIGR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiFLIO_ECOLI
AccessioniPrimary (citable) accession number: P22586
Secondary accession number(s): P33132
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: April 27, 2001
Last modified: November 2, 2016
This is version 116 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.