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P22579

- SIN3_YEAST

UniProt

P22579 - SIN3_YEAST

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Protein

Transcriptional regulatory protein SIN3

Gene
SIN3, CPE1, GAM2, RPD1, SDI1, SDS16, UME4, YOL004W
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic component of the RPD3 histone deacetylase complexes RPD3C(L) and RPD3C(S) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. SIN3 has also a RPD3 independent function required for normal longevity.18 Publications

GO - Molecular functioni

  1. identical protein binding Source: IntAct
  2. protein binding Source: IntAct
  3. transcription coactivator activity Source: SGD
  4. transcription corepressor activity Source: SGD

GO - Biological processi

  1. double-strand break repair via nonhomologous end joining Source: SGD
  2. histone deacetylation Source: SGD
  3. negative regulation of chromatin silencing at rDNA Source: SGD
  4. negative regulation of chromatin silencing at silent mating-type cassette Source: SGD
  5. negative regulation of chromatin silencing at telomere Source: SGD
  6. negative regulation of transcription during meiosis Source: SGD
  7. negative regulation of transcription from RNA polymerase II promoter Source: SGD
  8. negative regulation of transcription from RNA polymerase I promoter Source: SGD
  9. positive regulation of transcription from RNA polymerase II promoter Source: SGD
  10. positive regulation of transcription from RNA polymerase II promoter in response to heat stress Source: SGD
  11. regulation of DNA-dependent DNA replication initiation Source: SGD
  12. regulation of transcription involved in G2/M transition of mitotic cell cycle Source: SGD
  13. transcription, DNA-templated Source: UniProtKB-KW
  14. transfer RNA gene-mediated silencing Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Activator, Chromatin regulator, Repressor

Keywords - Biological processi

Cell cycle, Cell division, Transcription, Transcription regulation

Enzyme and pathway databases

BioCyciYEAST:G3O-33421-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Transcriptional regulatory protein SIN3
Gene namesi
Name:SIN3
Synonyms:CPE1, GAM2, RPD1, SDI1, SDS16, UME4
Ordered Locus Names:YOL004W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XV

Organism-specific databases

CYGDiYOL004w.
SGDiS000005364. SIN3.

Subcellular locationi

GO - Cellular componenti

  1. Rpd3L complex Source: SGD
  2. Rpd3S complex Source: SGD
  3. Sin3-type complex Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15361536Transcriptional regulatory protein SIN3PRO_0000121544Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei137 – 1371Phosphoserine1 Publication
Modified residuei303 – 3031Phosphothreonine1 Publication
Modified residuei304 – 3041Phosphothreonine2 Publications
Modified residuei316 – 3161Phosphoserine1 Publication
Modified residuei1046 – 10461Phosphoserine1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP22579.
PaxDbiP22579.
PeptideAtlasiP22579.

Expressioni

Gene expression databases

GenevestigatoriP22579.

Interactioni

Subunit structurei

Component of the RPD3C(L) complex composed of at least ASH1, CTI6, DEP1, PHO23, RPD3, RXT2, RXT3, SAP30, SDS3, SIN3, UME1 and UME6. Component of the RPD3C(S) complex composed of at least EAF3, RCO1, RPD3, SIN3, and UME1. Interacts with ESS1 and STB1.7 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
itself3EBI-17160,EBI-17160
OPI1P219575EBI-17160,EBI-12555
RPD3P3256111EBI-17160,EBI-15864

Protein-protein interaction databases

BioGridi34400. 533 interactions.
DIPiDIP-597N.
IntActiP22579. 84 interactions.
MINTiMINT-422975.
STRINGi4932.YOL004W.

Structurei

3D structure databases

ProteinModelPortaliP22579.
SMRiP22579. Positions 219-287.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini217 – 28771PAH 1Add
BLAST
Domaini404 – 47471PAH 2Add
BLAST
Domaini656 – 72772PAH 3Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi480 – 51940Gln-richAdd
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiCOG5602.
GeneTreeiENSGT00390000007239.
HOGENOMiHOG000248545.
KOiK11644.
OMAiREQKPIQ.
OrthoDBiEOG7T4MTQ.

Family and domain databases

Gene3Di1.20.1160.11. 3 hits.
InterProiIPR013194. HDAC_interact.
IPR003822. PAH.
[Graphical view]
PfamiPF02671. PAH. 3 hits.
PF08295. Sin3_corepress. 1 hit.
[Graphical view]
SMARTiSM00761. HDAC_interact. 1 hit.
[Graphical view]
SUPFAMiSSF47762. SSF47762. 3 hits.
PROSITEiPS51477. PAH. 3 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P22579-1 [UniParc]FASTAAdd to Basket

« Hide

MSQVWHNSNS QSNDVATSND ATGSNERNEK EPSLQGNKPG FVQQQQRITL     50
PSLSALSTKE EDRRDSNGQQ ALTSHAAHIL GYPPPHSNAM PSIATDSALK 100
QPHEYHPRPK SSSSSPSINA SLMNAGPAPL PTVGAASFSL SRFDNPLPIK 150
APVHTEEPKS YNGLQEEEKA TQRPQDCKEV PAGVQPADAP DPSSNHADAN 200
DDNNNNENSH DEDADYRPLN VKDALSYLEQ VKFQFSSRPD IYNLFLDIMK 250
DFKSQAIDTP GVIERVSTLF RGYPILIQGF NTFLPQGYRI ECSSNPDDPI 300
RVTTPMGTTT VNNNISPSGR GTTDAQELGS FPESDGNGVQ QPSNVPMVPS 350
SVYQSEQNQD QQQSLPLLAT SSGLPSIQQP EMPAHRQIPQ SQSLVPQEDA 400
KKNVDVEFSQ AISYVNKIKT RFADQPDIYK HFLEILQTYQ REQKPINEVY 450
AQVTHLFQNA PDLLEDFKKF LPDSSASANQ QVQHAQQHAQ QQHEAQMHAQ 500
AQAQAQAQAQ VEQQKQQQQF LYPASGYYGH PSNRGIPQQN LPPIGSFSPP 550
TNGSTVHEAY QDQQHMQPPH FMPLPSIVQH GPNMVHQGIA NENPPLSDLR 600
TSLTEQYAPS SIQHQQQHPQ SISPIANTQY GDIPVRPEID LDPSIVPVVP 650
EPTEPIENNI SLNEEVTFFE KAKRYIGNKH LYTEFLKILN LYSQDILDLD 700
DLVEKVDFYL GSNKELFTWF KNFVGYQEKT KCIENIVHEK HRLDLDLCEA 750
FGPSYKRLPK SDTFMPCSGR DDMCWEVLND EWVGHPVWAS EDSGFIAHRK 800
NQYEETLFKI EEERHEYDFY IESNLRTIQC LETIVNKIEN MTENEKANFK 850
LPPGLGHTSM TIYKKVIRKV YDKERGFEII DALHEHPAVT APVVLKRLKQ 900
KDEEWRRAQR EWNKVWRELE QKVFFKSLDH LGLTFKQADK KLLTTKQLIS 950
EISSIKVDQT NKKIHWLTPK PKSQLDFDFP DKNIFYDILC LADTFITHTT 1000
AYSNPDKERL KDLLKYFISL FFSISFEKIE ESLYSHKQNV SESSGSDDGS 1050
SIASRKRPYQ QEMSLLDILH RSRYQKLKRS NDEDGKVPQL SEPPEEEPNT 1100
IEEEELIDEE AKNPWLTGNL VEEANSQGII QNRSIFNLFA NTNIYIFFRH 1150
WTTIYERLLE IKQMNERVTK EINTRSTVTF AKDLDLLSSQ LSEMGLDFVG 1200
EDAYKQVLRL SRRLINGDLE HQWFEESLRQ AYNNKAFKLY TIDKVTQSLV 1250
KHAHTLMTDA KTAEIMALFV KDRNASTTSA KDQIIYRLQV RSHMSNTENM 1300
FRIEFDKRTL HVSIQYIALD DLTLKEPKAD EDKWKYYVTS YALPHPTEGI 1350
PHEKLKIPFL ERLIEFGQDI DGTEVDEEFS PEGISVSTLK IKIQPITYQL 1400
HIENGSYDVF TRKATNKYPT IANDNTQKGM VSQKKELISK FLDCAVGLRN 1450
NLDEAQKLSM QKKWENLKDS IAKTSAGNQG IESETEKGKI TKQEQSDNLD 1500
SSTASVLPAS ITTVPQDDNI ETTGNTESSD KGAKIQ 1536
Length:1,536
Mass (Da):174,839
Last modified:November 1, 1997 - v2
Checksum:i0834726312B13878
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti510 – 5101Q → QAQ1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M36822 Genomic DNA. Translation: AAA34839.1.
Z74746 Genomic DNA. Translation: CAA99003.1.
BK006948 Genomic DNA. Translation: DAA10779.1.
PIRiS66686. RGBYS3.
RefSeqiNP_014639.1. NM_001183258.1.

Genome annotation databases

EnsemblFungiiYOL004W; YOL004W; YOL004W.
GeneIDi854158.
KEGGisce:YOL004W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
M36822 Genomic DNA. Translation: AAA34839.1 .
Z74746 Genomic DNA. Translation: CAA99003.1 .
BK006948 Genomic DNA. Translation: DAA10779.1 .
PIRi S66686. RGBYS3.
RefSeqi NP_014639.1. NM_001183258.1.

3D structure databases

ProteinModelPortali P22579.
SMRi P22579. Positions 219-287.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 34400. 533 interactions.
DIPi DIP-597N.
IntActi P22579. 84 interactions.
MINTi MINT-422975.
STRINGi 4932.YOL004W.

Proteomic databases

MaxQBi P22579.
PaxDbi P22579.
PeptideAtlasi P22579.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YOL004W ; YOL004W ; YOL004W .
GeneIDi 854158.
KEGGi sce:YOL004W.

Organism-specific databases

CYGDi YOL004w.
SGDi S000005364. SIN3.

Phylogenomic databases

eggNOGi COG5602.
GeneTreei ENSGT00390000007239.
HOGENOMi HOG000248545.
KOi K11644.
OMAi REQKPIQ.
OrthoDBi EOG7T4MTQ.

Enzyme and pathway databases

BioCyci YEAST:G3O-33421-MONOMER.

Miscellaneous databases

NextBioi 975926.
PROi P22579.

Gene expression databases

Genevestigatori P22579.

Family and domain databases

Gene3Di 1.20.1160.11. 3 hits.
InterProi IPR013194. HDAC_interact.
IPR003822. PAH.
[Graphical view ]
Pfami PF02671. PAH. 3 hits.
PF08295. Sin3_corepress. 1 hit.
[Graphical view ]
SMARTi SM00761. HDAC_interact. 1 hit.
[Graphical view ]
SUPFAMi SSF47762. SSF47762. 3 hits.
PROSITEi PS51477. PAH. 3 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The Saccharomyces cerevisiae SIN3 gene, a negative regulator of HO, contains four paired amphipathic helix motifs."
    Wang H., Clark I., Nicholson P.R., Herskowitz I., Stillman D.J.
    Mol. Cell. Biol. 10:5927-5936(1990) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
    Strain: S288c / GRF88.
  2. "The nucleotide sequence of Saccharomyces cerevisiae chromosome XV."
    Dujon B., Albermann K., Aldea M., Alexandraki D., Ansorge W., Arino J., Benes V., Bohn C., Bolotin-Fukuhara M., Bordonne R., Boyer J., Camasses A., Casamayor A., Casas C., Cheret G., Cziepluch C., Daignan-Fornier B., Dang V.-D.
    , de Haan M., Delius H., Durand P., Fairhead C., Feldmann H., Gaillon L., Galisson F., Gamo F.-J., Gancedo C., Goffeau A., Goulding S.E., Grivell L.A., Habbig B., Hand N.J., Hani J., Hattenhorst U., Hebling U., Hernando Y., Herrero E., Heumann K., Hiesel R., Hilger F., Hofmann B., Hollenberg C.P., Hughes B., Jauniaux J.-C., Kalogeropoulos A., Katsoulou C., Kordes E., Lafuente M.J., Landt O., Louis E.J., Maarse A.C., Madania A., Mannhaupt G., Marck C., Martin R.P., Mewes H.-W., Michaux G., Paces V., Parle-McDermott A.G., Pearson B.M., Perrin A., Pettersson B., Poch O., Pohl T.M., Poirey R., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rechmann S., Schwager C., Schweizer M., Sor F., Sterky F., Tarassov I.A., Teodoru C., Tettelin H., Thierry A., Tobiasch E., Tzermia M., Uhlen M., Unseld M., Valens M., Vandenbol M., Vetter I., Vlcek C., Voet M., Volckaert G., Voss H., Wambutt R., Wedler H., Wiemann S., Winsor B., Wolfe K.H., Zollner A., Zumstein E., Kleine K.
    Nature 387:98-102(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  3. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  4. "RPD1 (SIN3/UME4) is required for maximal activation and repression of diverse yeast genes."
    Vidal M., Strich R., Easton Esposito R., Gaber R.F.
    Mol. Cell. Biol. 11:6306-6316(1991) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. "The Saccharomyces cerevisiae GAM2/SIN3 protein plays a role in both activation and repression of transcription."
    Yoshimoto H., Ohmae M., Yamashita I.
    Mol. Gen. Genet. 233:327-330(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  6. "Transcriptional repression in Saccharomyces cerevisiae by a SIN3-LexA fusion protein."
    Wang H., Stillman D.J.
    Mol. Cell. Biol. 13:1805-1814(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  7. "Evidence that the transcriptional regulators SIN3 and RPD3, and a novel gene (SDS3) with similar functions, are involved in transcriptional silencing in S. cerevisiae."
    Vannier D., Balderes D., Shore D.
    Genetics 144:1343-1353(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  8. "A large protein complex containing the yeast Sin3p and Rpd3p transcriptional regulators."
    Kasten M.M., Dorland S., Stillman D.J.
    Mol. Cell. Biol. 17:4852-4858(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, IDENTIFICATION IN THE RPD3 COMPLEX.
  9. "Identification of the Saccharomyces cerevisiae genes STB1-STB5 encoding Sin3p binding proteins."
    Kasten M.M., Stillman D.J.
    Mol. Gen. Genet. 256:376-386(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH STB1.
  10. "Targeted recruitment of the Sin3-Rpd3 histone deacetylase complex generates a highly localized domain of repressed chromatin in vivo."
    Kadosh D., Struhl K.
    Mol. Cell. Biol. 18:5121-5127(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  11. "Transcriptional repression by UME6 involves deacetylation of lysine 5 of histone H4 by RPD3."
    Rundlett S.E., Carmen A.A., Suka N., Turner B.M., Grunstein M.
    Nature 392:831-835(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  12. "A general requirement for the Sin3-Rpd3 histone deacetylase complex in regulating silencing in Saccharomyces cerevisiae."
    Sun Z.-W., Hampsey M.
    Genetics 152:921-932(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  13. "Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylase."
    Arevalo-Rodriguez M., Cardenas M.E., Wu X., Hanes S.D., Heitman J.
    EMBO J. 19:3739-3749(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH ESS1.
  14. "Combinatorial regulation of phospholipid biosynthetic gene expression by the UME6, SIN3 and RPD3 genes."
    Elkhaimi M., Kaadige M.R., Kamath D., Jackson J.C., Biliran H. Jr., Lopes J.M.
    Nucleic Acids Res. 28:3160-3167(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  15. "Identification of the Sin3-binding site in Ume6 defines a two-step process for conversion of Ume6 from a transcriptional repressor to an activator in yeast."
    Washburn B.K., Easton Esposito R.
    Mol. Cell. Biol. 21:2057-2069(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH UME6.
  16. "Opposite role of yeast ING family members in p53-dependent transcriptional activation."
    Nourani A., Howe L., Pray-Grant M.G., Workman J.L., Grant P.A., Cote J.
    J. Biol. Chem. 278:19171-19175(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE RPD3 COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  17. "Loss of Sin3/Rpd3 histone deacetylase restores the DNA damage response in checkpoint-deficient strains of Saccharomyces cerevisiae."
    Scott K.L., Plon S.E.
    Mol. Cell. Biol. 23:4522-4531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  18. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  19. "The unfolded protein response represses differentiation through the RPD3-SIN3 histone deacetylase."
    Schroeder M., Clark R., Liu C.Y., Kaufman R.J.
    EMBO J. 23:2281-2292(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  20. "The Rpd3-Sin3 histone deacetylase regulates replication timing and enables intra-S origin control in Saccharomyces cerevisiae."
    Aparicio J.G., Viggiani C.J., Gibson D.G., Aparicio O.M.
    Mol. Cell. Biol. 24:4769-4780(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  21. "The MAPK Hog1 recruits Rpd3 histone deacetylase to activate osmoresponsive genes."
    De Nadal E., Zapater M., Alepuz P.M., Sumoy L., Mas G., Posas F.
    Nature 427:370-374(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  22. "Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair."
    Jazayeri A., McAinsh A.D., Jackson S.P.
    Proc. Natl. Acad. Sci. U.S.A. 101:1644-1649(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION OF THE RPD3 COMPLEX.
  23. "Stable incorporation of sequence specific repressors Ash1 and Ume6 into the Rpd3L complex."
    Carrozza M.J., Florens L., Swanson S.K., Shia W.-J., Anderson S., Yates J., Washburn M.P., Workman J.L.
    Biochim. Biophys. Acta 1731:77-87(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION IN THE RPD3C(L) COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
  24. Cited for: IDENTIFICATION IN THE RPD3C(L) AND RPD3C(S) COMPLEXES, IDENTIFICATION BY MASS SPECTROMETRY, FUNCTION OF THE RPD3C(S) COMPLEX.
  25. "Genes determining yeast replicative life span in a long-lived genetic background."
    Kaeberlein M., Kirkland K.T., Fields S., Kennedy B.K.
    Mech. Ageing Dev. 126:491-504(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  26. "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
    Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
    J. Proteome Res. 6:1190-1197(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-304, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Strain: ADR376.
  27. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-137, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  28. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-303; THR-304; SER-316 AND SER-1046, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiSIN3_YEAST
AccessioniPrimary (citable) accession number: P22579
Secondary accession number(s): D6W263, Q08049
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: November 1, 1997
Last modified: June 11, 2014
This is version 139 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 1660 molecules/cell in log phase SD medium.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

External Data

Dasty 3

Similar proteinsi