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Protein

Beta-glucosidase 2

Gene

BGL2

Organism
Saccharomycopsis fibuligera (Yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway:icellulose degradation

This protein is involved in the pathway cellulose degradation, which is part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the pathway cellulose degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei299 – 2991By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Cellulose degradation, Polysaccharide degradation

Enzyme and pathway databases

UniPathwayiUPA00696.

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.
mycoCLAPiBGL3B_SACFI.

Names & Taxonomyi

Protein namesi
Recommended name:
Beta-glucosidase 2 (EC:3.2.1.21)
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene namesi
Name:BGL2
OrganismiSaccharomycopsis fibuligera (Yeast)
Taxonomic identifieri4944 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycopsidaceaeSaccharomycopsis

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Add
BLAST
Chaini18 – 880863Beta-glucosidase 2PRO_0000011780Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi24 – 241N-linked (GlcNAc...)Sequence Analysis
Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi271 – 2711N-linked (GlcNAc...)Sequence Analysis
Glycosylationi336 – 3361N-linked (GlcNAc...)Sequence Analysis
Glycosylationi343 – 3431N-linked (GlcNAc...)Sequence Analysis
Glycosylationi376 – 3761N-linked (GlcNAc...)Sequence Analysis
Glycosylationi548 – 5481N-linked (GlcNAc...)Sequence Analysis
Glycosylationi589 – 5891N-linked (GlcNAc...)Sequence Analysis
Glycosylationi712 – 7121N-linked (GlcNAc...)Sequence Analysis
Glycosylationi743 – 7431N-linked (GlcNAc...)Sequence Analysis
Glycosylationi794 – 7941N-linked (GlcNAc...)Sequence Analysis

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliP22507.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 3 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P22507-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLLILELLVL IIGLGVALPV QTHNLTDNQG FDEESSQWIS PHYYPTPQGG
60 70 80 90 100
RLQGVWQDAY TKAKALVSQM TIVEKVNLTT GTGWQLGPCV GNTGSVPRFG
110 120 130 140 150
IPNLCLQDGP LGVRLTDFST GYPSGMATGA TFNKDLFLQR GQALGHEFNS
160 170 180 190 200
KGVHIALGPA VGPLGVKARG GRNFEAFGSD PYLQGIAAAA TIKGLQENNV
210 220 230 240 250
MACVKHFIGN EQDIYRQPSN SKVDPEYDPA TKESISANIP DRAMHELYLW
260 270 280 290 300
PFADSIRAGV GSVMCSYNRV NNTYSCENSY MINHLLKEEL GFQGFVVSDW
310 320 330 340 350
AAQMSGAYSA ISGLDMSMPG ELLGGWNTGK SYWGQNLTKA VYNETVPIER
360 370 380 390 400
LDDMATRILA ALYATNSFPT KDRLPNFSSF TTKEYGNEFF VDKTSPVVKV
410 420 430 440 450
NHFVDPSNDF TEDTALKVAE ESIVLLKNEK NTLPISPNKV RKLLLSGIAA
460 470 480 490 500
GPDPKGYECS DQSCVDGALF EGWGSGSVGY PKYQVTPFEE ISANARKNKM
510 520 530 540 550
QFDYIRESFD LTQVSTVASD AHMSIVVVSA VSGEGYLIID GNRGDKNNVT
560 570 580 590 600
LWHNSDNLIK AVAENCANTV VVITSTGQVD VESFADHPNV TAIVWAGPLG
610 620 630 640 650
DRSGTAIANI LFGNANPSGH LPFTVAKSND DYIPIVTYNP PNGEPEDNTL
660 670 680 690 700
AEHDLLVDYR YFEEKNIEPR YAFGYGLSYN EYKVSNAKVS AAKKVDEELP
710 720 730 740 750
QPKLYLAEYS YNKTEEINNP EDAFFPSNAR RIQEFLYPYL DSNVTLKDGN
760 770 780 790 800
YEYPDGYSTE QRTTPIQPGG GLGGNDALWE VAYKVEVDVQ NLGNSTDKFV
810 820 830 840 850
PQLYLKHPED GKFETPVQLR GFEKVELSPG EKKTVEFELL RRDLSVWDTT
860 870 880
RQSWIVESGT YEALIGVAVN DIKTSVLFTI
Length:880
Mass (Da):96,799
Last modified:August 1, 1991 - v1
Checksum:iC95061283090814C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M22476 Genomic DNA. Translation: AAA34315.1.
PIRiB45956.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M22476 Genomic DNA. Translation: AAA34315.1.
PIRiB45956.

3D structure databases

ProteinModelPortaliP22507.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH3. Glycoside Hydrolase Family 3.
mycoCLAPiBGL3B_SACFI.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00696.

Family and domain databases

Gene3Di3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProiIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR30620. PTHR30620. 1 hit.
PfamiPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSiPR00133. GLHYDRLASE3.
SUPFAMiSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEiPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Nucleotide sequences of Saccharomycopsis fibuligera genes for extracellular beta-glucosidases as expressed in Saccharomyces cerevisiae."
    Machida M., Ohtsuki I., Fukui S., Yamashita I.
    Appl. Environ. Microbiol. 54:3147-3155(1988) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiBGL2_SACFI
AccessioniPrimary (citable) accession number: P22507
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 1, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.