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P22507 (BGL2_SACFI) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Beta-glucosidase 2

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase
Cellobiase
Gentiobiase
Gene names
Name:BGL2
OrganismSaccharomycopsis fibuligera (Yeast)
Taxonomic identifier4944 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycopsidaceaeSaccharomycopsis

Protein attributes

Sequence length880 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717
Chain18 – 880863Beta-glucosidase 2
PRO_0000011780

Sites

Active site2991 By similarity

Amino acid modifications

Glycosylation241N-linked (GlcNAc...) Potential
Glycosylation771N-linked (GlcNAc...) Potential
Glycosylation2711N-linked (GlcNAc...) Potential
Glycosylation3361N-linked (GlcNAc...) Potential
Glycosylation3431N-linked (GlcNAc...) Potential
Glycosylation3761N-linked (GlcNAc...) Potential
Glycosylation5481N-linked (GlcNAc...) Potential
Glycosylation5891N-linked (GlcNAc...) Potential
Glycosylation7121N-linked (GlcNAc...) Potential
Glycosylation7431N-linked (GlcNAc...) Potential
Glycosylation7941N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P22507 [UniParc].

Last modified August 1, 1991. Version 1.
Checksum: C95061283090814C

FASTA88096,799
        10         20         30         40         50         60 
MLLILELLVL IIGLGVALPV QTHNLTDNQG FDEESSQWIS PHYYPTPQGG RLQGVWQDAY 

        70         80         90        100        110        120 
TKAKALVSQM TIVEKVNLTT GTGWQLGPCV GNTGSVPRFG IPNLCLQDGP LGVRLTDFST 

       130        140        150        160        170        180 
GYPSGMATGA TFNKDLFLQR GQALGHEFNS KGVHIALGPA VGPLGVKARG GRNFEAFGSD 

       190        200        210        220        230        240 
PYLQGIAAAA TIKGLQENNV MACVKHFIGN EQDIYRQPSN SKVDPEYDPA TKESISANIP 

       250        260        270        280        290        300 
DRAMHELYLW PFADSIRAGV GSVMCSYNRV NNTYSCENSY MINHLLKEEL GFQGFVVSDW 

       310        320        330        340        350        360 
AAQMSGAYSA ISGLDMSMPG ELLGGWNTGK SYWGQNLTKA VYNETVPIER LDDMATRILA 

       370        380        390        400        410        420 
ALYATNSFPT KDRLPNFSSF TTKEYGNEFF VDKTSPVVKV NHFVDPSNDF TEDTALKVAE 

       430        440        450        460        470        480 
ESIVLLKNEK NTLPISPNKV RKLLLSGIAA GPDPKGYECS DQSCVDGALF EGWGSGSVGY 

       490        500        510        520        530        540 
PKYQVTPFEE ISANARKNKM QFDYIRESFD LTQVSTVASD AHMSIVVVSA VSGEGYLIID 

       550        560        570        580        590        600 
GNRGDKNNVT LWHNSDNLIK AVAENCANTV VVITSTGQVD VESFADHPNV TAIVWAGPLG 

       610        620        630        640        650        660 
DRSGTAIANI LFGNANPSGH LPFTVAKSND DYIPIVTYNP PNGEPEDNTL AEHDLLVDYR 

       670        680        690        700        710        720 
YFEEKNIEPR YAFGYGLSYN EYKVSNAKVS AAKKVDEELP QPKLYLAEYS YNKTEEINNP 

       730        740        750        760        770        780 
EDAFFPSNAR RIQEFLYPYL DSNVTLKDGN YEYPDGYSTE QRTTPIQPGG GLGGNDALWE 

       790        800        810        820        830        840 
VAYKVEVDVQ NLGNSTDKFV PQLYLKHPED GKFETPVQLR GFEKVELSPG EKKTVEFELL 

       850        860        870        880 
RRDLSVWDTT RQSWIVESGT YEALIGVAVN DIKTSVLFTI 

« Hide

References

[1]"Nucleotide sequences of Saccharomycopsis fibuligera genes for extracellular beta-glucosidases as expressed in Saccharomyces cerevisiae."
Machida M., Ohtsuki I., Fukui S., Yamashita I.
Appl. Environ. Microbiol. 54:3147-3155(1988) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M22476 Genomic DNA. Translation: AAA34315.1.
PIRB45956.

3D structure databases

ProteinModelPortalP22507.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH3. Glycoside Hydrolase Family 3.
mycoCLAPBGL3B_SACFI.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGL2_SACFI
AccessionPrimary (citable) accession number: P22507
Entry history
Integrated into UniProtKB/Swiss-Prot: August 1, 1991
Last sequence update: August 1, 1991
Last modified: October 16, 2013
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries